Ulcerative colitis screening: Difference between revisions
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There is a significantly increased risk of [[colorectal cancer]] in patients with ulcerative colitis after 10 years if involvement is beyond the [[Colon (anatomy)|splenic flexure]]. Those with only [[proctitis]] or rectosigmoiditis usually have no increased risk.<ref name=ACGGuideline/> It is recommended that patients have screening colonoscopies with random biopsies to look for [[dysplasia]] after eight years of disease activity<ref>Leighton JA, Shen B, Baron TH, Adler DG, Davila R, Egan JV, Faigel DO, Gan SI, Hirota WK, Lichtenstein D, Qureshi WA, Rajan E, Zuckerman MJ, VanGuilder T, Fanelli RD; Standards of Practice Committee, American Society for Gastrointestinal Endoscopy. ASGE guideline: endoscopy in the diagnosis and treatment of inflammatory bowel disease. ''Gastrointest Endosc'' 2006;63:558-65. PMID 16564852.</ref> | There is a significantly increased risk of [[colorectal cancer]] in patients with ulcerative colitis after 10 years if involvement is beyond the [[Colon (anatomy)|splenic flexure]]. Those with only [[proctitis]] or rectosigmoiditis usually have no increased risk.<ref name=ACGGuideline>Ulcerative Colitis Practice Guidelines in Adults, Am. Coll. Gastroenterology, 2004. [http://www.acg.gi.org/physicians/guidelines/UlcerativeColitisUpdate.pdf PDF]</ref> It is recommended that patients have screening colonoscopies with random biopsies to look for [[dysplasia]] after eight years of disease activity<ref>Leighton JA, Shen B, Baron TH, Adler DG, Davila R, Egan JV, Faigel DO, Gan SI, Hirota WK, Lichtenstein D, Qureshi WA, Rajan E, Zuckerman MJ, VanGuilder T, Fanelli RD; Standards of Practice Committee, American Society for Gastrointestinal Endoscopy. ASGE guideline: endoscopy in the diagnosis and treatment of inflammatory bowel disease. ''Gastrointest Endosc'' 2006;63:558-65. PMID 16564852.</ref> | ||
The American Cancer Society recommends having first screening: | The American Cancer Society recommends having first screening: | ||
Revision as of 20:31, 28 August 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Screening
There is a significantly increased risk of colorectal cancer in patients with ulcerative colitis after 10 years if involvement is beyond the splenic flexure. Those with only proctitis or rectosigmoiditis usually have no increased risk.[1] It is recommended that patients have screening colonoscopies with random biopsies to look for dysplasia after eight years of disease activity[2]
The American Cancer Society recommends having first screening:
- 8 years after you are diagnosed with severe disease, or when most of, or the entire, large intestine is involved
- 12 - 15 years after diagnosis when only the left side of the large intestine is involved
Have follow-up examinations every 1 - 2 years.
References
- ↑ Ulcerative Colitis Practice Guidelines in Adults, Am. Coll. Gastroenterology, 2004. PDF
- ↑ Leighton JA, Shen B, Baron TH, Adler DG, Davila R, Egan JV, Faigel DO, Gan SI, Hirota WK, Lichtenstein D, Qureshi WA, Rajan E, Zuckerman MJ, VanGuilder T, Fanelli RD; Standards of Practice Committee, American Society for Gastrointestinal Endoscopy. ASGE guideline: endoscopy in the diagnosis and treatment of inflammatory bowel disease. Gastrointest Endosc 2006;63:558-65. PMID 16564852.