Acromegaly natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Natural History

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Complications

• Arthritis
• Cardiovascular disease
• Carpal tunnel syndrome
• Colonic polyps
• Glucose intolerance or diabetes
• High blood pressure
• Hypopituitarism
• Sleep apnea
• Spinal cord compression
• Uterine fibroids
• Vision abnormalities

Prognosis

Pituitary surgery is successful in most patients, depending on the size of the tumor and the experience of the surgeon. Without treatment the symptoms will get worse, and the risk of cardiovascular disease increases.