ADAM33: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''Disintegrin and metalloproteinase domain-containing protein 33''' is an [[enzyme]] that in humans is encoded by the ''ADAM33'' [[gene]].<ref name="pmid11814695">{{cite journal | vauthors = Yoshinaka T, Nishii K, Yamada K, Sawada H, Nishiwaki E, Smith K, Yoshino K, Ishiguro H, Higashiyama S | title = Identification and characterization of novel mouse and human ADAM33s with potential metalloprotease activity | journal = Gene | volume = 282 | issue = 1-2 | pages = 227–36 | date = January 2002 | pmid = 11814695 | pmc =  | doi = 10.1016/S0378-1119(01)00818-6 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ADAM33 ADAM metallopeptidase domain 33| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=80332| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image = PBB_Protein_ADAM33_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1r54.
| PDB = {{PDB2|1r54}}, {{PDB2|1r55}}
| Name = ADAM metallopeptidase domain 33
| HGNCid = 15478
| Symbol = ADAM33
| AltSymbols =; DJ964F7.1; DKFZp434K0521; FLJ35308; FLJ36751; MGC149823; MGC71889
| OMIM = 607114
| ECnumber = 
| Homologene = 11881
| MGIid = 1341813
| Function = {{GNF_GO|id=GO:0004222 |text = metalloendopeptidase activity}} {{GNF_GO|id=GO:0008237 |text = metallopeptidase activity}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0006508 |text = proteolysis}} {{GNF_GO|id=GO:0007229 |text = integrin-mediated signaling pathway}} {{GNF_GO|id=GO:0042035 |text = regulation of cytokine biosynthetic process}} {{GNF_GO|id=GO:0042127 |text = regulation of cell proliferation}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 80332
    | Hs_Ensembl = ENSG00000149451
    | Hs_RefseqProtein = NP_079496
    | Hs_RefseqmRNA = NM_025220
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 20
    | Hs_GenLoc_start = 3596612
    | Hs_GenLoc_end = 3611337
    | Hs_Uniprot = Q9BZ11
    | Mm_EntrezGene = 110751
    | Mm_Ensembl = ENSMUSG00000027318
    | Mm_RefseqmRNA = NM_033615
    | Mm_RefseqProtein = NP_291093
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 2
    | Mm_GenLoc_start = 130742266
    | Mm_GenLoc_end = 130755255
    | Mm_Uniprot = Q6TYY9
  }}
}}
'''ADAM metallopeptidase domain 33''', also known as '''ADAM33''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ADAM33 ADAM metallopeptidase domain 33| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=80332| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
This gene encodes a member of the ADAM ([[a disintegrin and metalloprotease]] domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom [[disintegrins]], and have been implicated in a variety of biological processes involving cell-cell and cell-[[extracellular matrix|matrix]] interactions, including [[fertilization]], muscle development, and [[neurogenesis]]. This protein is a type I [[transmembrane protein]] implicated in [[asthma]] and [[bronchial hyperresponsiveness]].<ref>{{Cite journal|last=Davies|first=Elizabeth R.|last2=Kelly|first2=Joanne F.C.|last3=Howarth|first3=Peter H.|last4=Wilson|first4=David I.|last5=Holgate|first5=Stephen T.|last6=Davies|first6=Donna E.|last7=Whitsett|first7=Jeffrey A.|last8=Haitchi|first8=Hans Michael | name-list-format = vanc |date=2016-07-21|title=Soluble ADAM33 initiates airway remodeling to promote susceptibility for allergic asthma in early life|url=https://insight.jci.org/articles/view/87632|journal=JCI Insight|language=en|volume=1|issue=11|doi=10.1172/jci.insight.87632|issn=0021-9738|pmid=27489884|pmc=4968941}}</ref> Alternative splicing of this gene results in two transcript variants encoding different isoforms.<ref name="entrez"/>
{{PBB_Summary
| section_title =
| summary_text = This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing of this gene results in two transcript variants encoding different isoforms.<ref name="entrez">{{cite web | title = Entrez Gene: ADAM33 ADAM metallopeptidase domain 33| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=80332| accessdate = }}</ref>
}}


==References==
== References ==
{{reflist|2}}
{{reflist}}
==Further reading==
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Holgate ST, Davies DE, Rorke S, Cakebread J, Murphy G, Powell RM, Holloway JW | title = ADAM 33 and its association with airway remodeling and hyperresponsiveness in asthma | journal = Clinical Reviews in Allergy & Immunology | volume = 27 | issue = 1 | pages = 23–34 | date = August 2004 | pmid = 15347848 | doi = 10.1385/CRIAI:27:1:023 }}
| citations =
* {{cite journal | vauthors = Holloway JW, Davies DE, Powell R, Haitchi HM, Keith TP, Holgate ST | title = The discovery and role of ADAM33, a new candidate gene for asthma | journal = Expert Reviews in Molecular Medicine | volume = 6 | issue = 17 | pages = 1–12 | date = August 2004 | pmid = 15387895 | doi = 10.1017/S1462399404007963 }}
*{{cite journal | author=Holgate ST, Davies DE, Rorke S, ''et al.'' |title=ADAM 33 and its association with airway remodeling and hyperresponsiveness in asthma. |journal=Clinical reviews in allergy & immunology |volume=27 |issue= 1 |pages= 23-34 |year= 2005 |pmid= 15347848 |doi= }}
* {{cite journal | vauthors = Holgate ST, Yang Y, Haitchi HM, Powell RM, Holloway JW, Yoshisue H, Pang YY, Cakebread J, Davies DE | title = The genetics of asthma: ADAM33 as an example of a susceptibility gene | journal = Proceedings of the American Thoracic Society | volume = 3 | issue = 5 | pages = 440–3 | date = July 2006 | pmid = 16799089 | doi = 10.1513/pats.200603-026AW }}
*{{cite journal | author=Holloway JW, Davies DE, Powell R, ''et al.'' |title=The discovery and role of ADAM33, a new candidate gene for asthma. |journal=Expert reviews in molecular medicine |volume=6 |issue= 17 |pages= 1-12 |year= 2007 |pmid= 15387895 |doi= 10.1017/S1462399404007963 }}
* {{cite journal | vauthors = Van Eerdewegh P, Little RD, Dupuis J, Del Mastro RG, Falls K, Simon J, Torrey D, Pandit S, McKenny J, Braunschweiger K, Walsh A, Liu Z, Hayward B, Folz C, Manning SP, Bawa A, Saracino L, Thackston M, Benchekroun Y, Capparell N, Wang M, Adair R, Feng Y, Dubois J, FitzGerald MG, Huang H, Gibson R, Allen KM, Pedan A, Danzig MR, Umland SP, Egan RW, Cuss FM, Rorke S, Clough JB, Holloway JW, Holgate ST, Keith TP | title = Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness | journal = Nature | volume = 418 | issue = 6896 | pages = 426–30 | date = July 2002 | pmid = 12110844 | doi = 10.1038/nature00878 }}
*{{cite journal | author=Holgate ST, Yang Y, Haitchi HM, ''et al.'' |title=The genetics of asthma: ADAM33 as an example of a susceptibility gene. |journal=Proceedings of the American Thoracic Society |volume=3 |issue= 5 |pages= 440-3 |year= 2006 |pmid= 16799089 |doi= 10.1513/pats.200603-026AW }}
* {{cite journal | vauthors = Garlisi CG, Zou J, Devito KE, Tian F, Zhu FX, Liu J, Shah H, Wan Y, Motasim Billah M, Egan RW, Umland SP | title = Human ADAM33: protein maturation and localization | journal = Biochemical and Biophysical Research Communications | volume = 301 | issue = 1 | pages = 35–43 | date = January 2003 | pmid = 12535637 | doi = 10.1016/S0006-291X(02)02976-5 }}
*{{cite journal | author=Deloukas P, Matthews LH, Ashurst J, ''et al.'' |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865-71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a }}
* {{cite journal | vauthors = Chae SC, Yoon KH, Chung HT | title = Identification of novel polymorphisms in the Adam33 gene | journal = Journal of Human Genetics | volume = 48 | issue = 5 | pages = 278–81 | year = 2003 | pmid = 12768445 | doi = 10.1007/s10038-003-0019-1 }}
*{{cite journal  | author=Yoshinaka T, Nishii K, Yamada K, ''et al.'' |title=Identification and characterization of novel mouse and human ADAM33s with potential metalloprotease activity. |journal=Gene |volume=282 |issue= 1-2 |pages= 227-36 |year= 2002 |pmid= 11814695 |doi=  }}
* {{cite journal | vauthors = Howard TD, Postma DS, Jongepier H, Moore WC, Koppelman GH, Zheng SL, Xu J, Bleecker ER, Meyers DA | title = Association of a disintegrin and metalloprotease 33 (ADAM33) gene with asthma in ethnically diverse populations | journal = The Journal of Allergy and Clinical Immunology | volume = 112 | issue = 4 | pages = 717–22 | date = October 2003 | pmid = 14564349 | doi = 10.1016/s0091-6749(03)01939-0 }}
*{{cite journal  | author=Van Eerdewegh P, Little RD, Dupuis J, ''et al.'' |title=Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. |journal=Nature |volume=418 |issue= 6896 |pages= 426-30 |year= 2002 |pmid= 12110844 |doi= 10.1038/nature00878 }}
* {{cite journal | vauthors = Orth P, Reichert P, Wang W, Prosise WW, Yarosh-Tomaine T, Hammond G, Ingram RN, Xiao L, Mirza UA, Zou J, Strickland C, Taremi SS, Le HV, Madison V | title = Crystal structure of the catalytic domain of human ADAM33 | journal = Journal of Molecular Biology | volume = 335 | issue = 1 | pages = 129–37 | date = January 2004 | pmid = 14659745 | doi = 10.1016/j.jmb.2003.10.037 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
* {{cite journal | vauthors = Zou J, Zhu F, Liu J, Wang W, Zhang R, Garlisi CG, Liu YH, Wang S, Shah H, Wan Y, Umland SP | title = Catalytic activity of human ADAM33 | journal = The Journal of Biological Chemistry | volume = 279 | issue = 11 | pages = 9818–30 | date = March 2004 | pmid = 14676211 | doi = 10.1074/jbc.M309696200 }}
*{{cite journal  | author=Garlisi CG, Zou J, Devito KE, ''et al.'' |title=Human ADAM33: protein maturation and localization. |journal=Biochem. Biophys. Res. Commun. |volume=301 |issue= 1 |pages= 35-43 |year= 2003 |pmid= 12535637 |doi= }}
* {{cite journal | vauthors = Powell RM, Wicks J, Holloway JW, Holgate ST, Davies DE | title = The splicing and fate of ADAM33 transcripts in primary human airways fibroblasts | journal = American Journal of Respiratory Cell and Molecular Biology | volume = 31 | issue = 1 | pages = 13–21 | date = July 2004 | pmid = 14742294 | doi = 10.1165/rcmb.2003-0330OC }}
*{{cite journal | author=Chae SC, Yoon KH, Chung HT |title=Identification of novel polymorphisms in the Adam33 gene. |journal=J. Hum. Genet. |volume=48 |issue= 5 |pages= 278-81 |year= 2003 |pmid= 12768445 |doi= 10.1007/s10038-003-0019-1 }}
* {{cite journal | vauthors = Haitchi HM, Powell RM, Shaw TJ, Howarth PH, Wilson SJ, Wilson DI, Holgate ST, Davies DE | title = ADAM33 expression in asthmatic airways and human embryonic lungs | journal = American Journal of Respiratory and Critical Care Medicine | volume = 171 | issue = 9 | pages = 958–65 | date = May 2005 | pmid = 15709049 | doi = 10.1164/rccm.200409-1251OC }}
*{{cite journal | author=Clark HF, Gurney AL, Abaya E, ''et al.'' |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265-70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 }}
* {{cite journal | vauthors = Zou J, Zhang R, Zhu F, Liu J, Madison V, Umland SP | title = ADAM33 enzyme properties and substrate specificity | journal = Biochemistry | volume = 44 | issue = 11 | pages = 4247–56 | date = March 2005 | pmid = 15766253 | doi = 10.1021/bi0476230 }}
*{{cite journal  | author=Howard TD, Postma DS, Jongepier H, ''et al.'' |title=Association of a disintegrin and metalloprotease 33 (ADAM33) gene with asthma in ethnically diverse populations. |journal=J. Allergy Clin. Immunol. |volume=112 |issue= 4 |pages= 717-22 |year= 2003 |pmid= 14564349 |doi= 10.1016/S0091 }}
* {{cite journal | vauthors = Simpson A, Maniatis N, Jury F, Cakebread JA, Lowe LA, Holgate ST, Woodcock A, Ollier WE, Collins A, Custovic A, Holloway JW, John SL | title = Polymorphisms in a disintegrin and metalloprotease 33 (ADAM33) predict impaired early-life lung function | journal = American Journal of Respiratory and Critical Care Medicine | volume = 172 | issue = 1 | pages = 55–60 | date = July 2005 | pmid = 15805180 | doi = 10.1164/rccm.200412-1708OC }}
*{{cite journal | author=Orth P, Reichert P, Wang W, ''et al.'' |title=Crystal structure of the catalytic domain of human ADAM33. |journal=J. Mol. Biol. |volume=335 |issue= 1 |pages= 129-37 |year= 2004 |pmid= 14659745 |doi= }}
*{{cite journal | author=Zou J, Zhu F, Liu J, ''et al.'' |title=Catalytic activity of human ADAM33. |journal=J. Biol. Chem. |volume=279 |issue= 11 |pages= 9818-30 |year= 2004 |pmid= 14676211 |doi= 10.1074/jbc.M309696200 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Powell RM, Wicks J, Holloway JW, ''et al.'' |title=The splicing and fate of ADAM33 transcripts in primary human airways fibroblasts. |journal=Am. J. Respir. Cell Mol. Biol. |volume=31 |issue= 1 |pages= 13-21 |year= 2004 |pmid= 14742294 |doi= 10.1165/rcmb.2003-0330OC }}
*{{cite journal | author=Haitchi HM, Powell RM, Shaw TJ, ''et al.'' |title=ADAM33 expression in asthmatic airways and human embryonic lungs. |journal=Am. J. Respir. Crit. Care Med. |volume=171 |issue= 9 |pages= 958-65 |year= 2005 |pmid= 15709049 |doi= 10.1164/rccm.200409-1251OC }}
*{{cite journal | author=Zou J, Zhang R, Zhu F, ''et al.'' |title=ADAM33 enzyme properties and substrate specificity. |journal=Biochemistry |volume=44 |issue= 11 |pages= 4247-56 |year= 2005 |pmid= 15766253 |doi= 10.1021/bi0476230 }}
*{{cite journal | author=Simpson A, Maniatis N, Jury F, ''et al.'' |title=Polymorphisms in a disintegrin and metalloprotease 33 (ADAM33) predict impaired early-life lung function. |journal=Am. J. Respir. Crit. Care Med. |volume=172 |issue= 1 |pages= 55-60 |year= 2005 |pmid= 15805180 |doi= 10.1164/rccm.200412-1708OC }}
}}
{{refend}}
{{refend}}
== External links ==
* The [[MEROPS]] online database for peptidases and their inhibitors: [http://merops.sanger.ac.uk/cgi-bin/merops.cgi?id=M12.244 M12.244]
* {{UCSC gene info|ADAM33}}
{{PDB Gallery|geneid=80332}}
{{Metalloproteinases}}


{{gene-20-stub}}
{{gene-20-stub}}
{{WikiDoc Sources}}

Revision as of 01:59, 27 October 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Disintegrin and metalloproteinase domain-containing protein 33 is an enzyme that in humans is encoded by the ADAM33 gene.[1][2]

Function

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness.[3] Alternative splicing of this gene results in two transcript variants encoding different isoforms.[2]

References

  1. ↑ Yoshinaka T, Nishii K, Yamada K, Sawada H, Nishiwaki E, Smith K, Yoshino K, Ishiguro H, Higashiyama S (January 2002). "Identification and characterization of novel mouse and human ADAM33s with potential metalloprotease activity". Gene. 282 (1–2): 227–36. doi:10.1016/S0378-1119(01)00818-6. PMID 11814695.
  2. ↑ 2.0 2.1 "Entrez Gene: ADAM33 ADAM metallopeptidase domain 33".
  3. ↑ Davies ER, Kelly JF, Howarth PH, Wilson DI, Holgate ST, Davies DE, Whitsett JA, Haitchi HM (2016-07-21). "Soluble ADAM33 initiates airway remodeling to promote susceptibility for allergic asthma in early life". JCI Insight. 1 (11). doi:10.1172/jci.insight.87632. ISSN 0021-9738. PMC 4968941. PMID 27489884.

Further reading

  • Holgate ST, Davies DE, Rorke S, Cakebread J, Murphy G, Powell RM, Holloway JW (August 2004). "ADAM 33 and its association with airway remodeling and hyperresponsiveness in asthma". Clinical Reviews in Allergy & Immunology. 27 (1): 23–34. doi:10.1385/CRIAI:27:1:023. PMID 15347848.
  • Holloway JW, Davies DE, Powell R, Haitchi HM, Keith TP, Holgate ST (August 2004). "The discovery and role of ADAM33, a new candidate gene for asthma". Expert Reviews in Molecular Medicine. 6 (17): 1–12. doi:10.1017/S1462399404007963. PMID 15387895.
  • Holgate ST, Yang Y, Haitchi HM, Powell RM, Holloway JW, Yoshisue H, Pang YY, Cakebread J, Davies DE (July 2006). "The genetics of asthma: ADAM33 as an example of a susceptibility gene". Proceedings of the American Thoracic Society. 3 (5): 440–3. doi:10.1513/pats.200603-026AW. PMID 16799089.
  • Van Eerdewegh P, Little RD, Dupuis J, Del Mastro RG, Falls K, Simon J, Torrey D, Pandit S, McKenny J, Braunschweiger K, Walsh A, Liu Z, Hayward B, Folz C, Manning SP, Bawa A, Saracino L, Thackston M, Benchekroun Y, Capparell N, Wang M, Adair R, Feng Y, Dubois J, FitzGerald MG, Huang H, Gibson R, Allen KM, Pedan A, Danzig MR, Umland SP, Egan RW, Cuss FM, Rorke S, Clough JB, Holloway JW, Holgate ST, Keith TP (July 2002). "Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness". Nature. 418 (6896): 426–30. doi:10.1038/nature00878. PMID 12110844.
  • Garlisi CG, Zou J, Devito KE, Tian F, Zhu FX, Liu J, Shah H, Wan Y, Motasim Billah M, Egan RW, Umland SP (January 2003). "Human ADAM33: protein maturation and localization". Biochemical and Biophysical Research Communications. 301 (1): 35–43. doi:10.1016/S0006-291X(02)02976-5. PMID 12535637.
  • Chae SC, Yoon KH, Chung HT (2003). "Identification of novel polymorphisms in the Adam33 gene". Journal of Human Genetics. 48 (5): 278–81. doi:10.1007/s10038-003-0019-1. PMID 12768445.
  • Howard TD, Postma DS, Jongepier H, Moore WC, Koppelman GH, Zheng SL, Xu J, Bleecker ER, Meyers DA (October 2003). "Association of a disintegrin and metalloprotease 33 (ADAM33) gene with asthma in ethnically diverse populations". The Journal of Allergy and Clinical Immunology. 112 (4): 717–22. doi:10.1016/s0091-6749(03)01939-0. PMID 14564349.
  • Orth P, Reichert P, Wang W, Prosise WW, Yarosh-Tomaine T, Hammond G, Ingram RN, Xiao L, Mirza UA, Zou J, Strickland C, Taremi SS, Le HV, Madison V (January 2004). "Crystal structure of the catalytic domain of human ADAM33". Journal of Molecular Biology. 335 (1): 129–37. doi:10.1016/j.jmb.2003.10.037. PMID 14659745.
  • Zou J, Zhu F, Liu J, Wang W, Zhang R, Garlisi CG, Liu YH, Wang S, Shah H, Wan Y, Umland SP (March 2004). "Catalytic activity of human ADAM33". The Journal of Biological Chemistry. 279 (11): 9818–30. doi:10.1074/jbc.M309696200. PMID 14676211.
  • Powell RM, Wicks J, Holloway JW, Holgate ST, Davies DE (July 2004). "The splicing and fate of ADAM33 transcripts in primary human airways fibroblasts". American Journal of Respiratory Cell and Molecular Biology. 31 (1): 13–21. doi:10.1165/rcmb.2003-0330OC. PMID 14742294.
  • Haitchi HM, Powell RM, Shaw TJ, Howarth PH, Wilson SJ, Wilson DI, Holgate ST, Davies DE (May 2005). "ADAM33 expression in asthmatic airways and human embryonic lungs". American Journal of Respiratory and Critical Care Medicine. 171 (9): 958–65. doi:10.1164/rccm.200409-1251OC. PMID 15709049.
  • Zou J, Zhang R, Zhu F, Liu J, Madison V, Umland SP (March 2005). "ADAM33 enzyme properties and substrate specificity". Biochemistry. 44 (11): 4247–56. doi:10.1021/bi0476230. PMID 15766253.
  • Simpson A, Maniatis N, Jury F, Cakebread JA, Lowe LA, Holgate ST, Woodcock A, Ollier WE, Collins A, Custovic A, Holloway JW, John SL (July 2005). "Polymorphisms in a disintegrin and metalloprotease 33 (ADAM33) predict impaired early-life lung function". American Journal of Respiratory and Critical Care Medicine. 172 (1): 55–60. doi:10.1164/rccm.200412-1708OC. PMID 15805180.

External links


Retrieved from "https://www.wikidoc.org/index.php?title=ADAM33&oldid=1419503"