CDR2 (gene): Difference between revisions

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{{Infobox_gene}}
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'''Cerebellar degeneration-related protein 2''' is a [[protein]] that in [[humans]] is encoded by the ''CDR2'' [[gene]].<ref name="pmid2014264">{{cite journal | vauthors = Fathallah-Shaykh H, Wolf S, Wong E, Posner JB, Furneaux HM | title = Cloning of a leucine-zipper protein recognized by the sera of patients with antibody-associated paraneoplastic cerebellar degeneration | journal = Proc Natl Acad Sci U S A | volume = 88 | issue = 8 | pages = 3451–4 |date=May 1991 | pmid = 2014264 | pmc = 51465 | doi =10.1073/pnas.88.8.3451 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CDR2 cerebellar degeneration-related protein 2, 62kDa| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1039| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Cerebellar degeneration-related protein 2, 62kDa
| HGNCid = 1799
| Symbol = CDR2
| AltSymbols =; CDR62; Yo
| OMIM = 117340
| ECnumber = 
| Homologene = 7262
| MGIid = 1100885
| GeneAtlas_image1 = PBB_GE_CDR2_209501_at_tn.png
| Function = {{GNF_GO|id=GO:0003674 |text = molecular_function}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005737 |text = cytoplasm}}
| Process =  
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 1039
    | Hs_Ensembl = ENSG00000140743
    | Hs_RefseqProtein = NP_001793
    | Hs_RefseqmRNA = NM_001802
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 16
    | Hs_GenLoc_start = 22264758
    | Hs_GenLoc_end = 22293439
    | Hs_Uniprot = Q01850
    | Mm_EntrezGene = 12585
    | Mm_Ensembl = ENSMUSG00000030878
    | Mm_RefseqmRNA = NM_007672
    | Mm_RefseqProtein = NP_031698
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 7
    | Mm_GenLoc_start = 120748185
    | Mm_GenLoc_end = 120773433
    | Mm_Uniprot = Q3TAP7
  }}
}}
'''Cerebellar degeneration-related protein 2, 62kDa''', also known as '''CDR2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CDR2 cerebellar degeneration-related protein 2, 62kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1039| accessdate = }}</ref>


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| summary_text =  
}}
}}
==See also==
* [[Cerebellar degeneration-related protein 1]]


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Gress T, Baldini A, Rocchi M, ''et al.'' |title=In situ mapping of the gene coding for a leucine zipper DNA binding protein (CDR62) to 16p12-16p13.1. |journal=Genomics |volume=13 |issue= 4 |pages= 1340-2 |year= 1992 |pmid= 1505970 |doi=  }}
*{{cite journal  | vauthors=Gress T, Baldini A, Rocchi M |title=In situ mapping of the gene coding for a leucine zipper DNA binding protein (CDR62) to 16p12-16p13.1. |journal=Genomics |volume=13 |issue= 4 |pages= 1340–2 |year= 1992 |pmid= 1505970 |doi=10.1016/0888-7543(92)90063-X |display-authors=etal}}
*{{cite journal  | author=Sakai K, Mitchell DJ, Tsukamoto T, Steinman L |title=Isolation of a complementary DNA clone encoding an autoantigen recognized by an anti-neuronal cell antibody from a patient with paraneoplastic cerebellar degeneration. |journal=Ann. Neurol. |volume=30 |issue= 5 |pages= 738 |year= 1992 |pmid= 1763903 |doi= 10.1002/ana.410300523 }}
*{{cite journal  | vauthors=Sakai K, Mitchell DJ, Tsukamoto T, Steinman L |title=Isolation of a complementary DNA clone encoding an autoantigen recognized by an anti-neuronal cell antibody from a patient with paraneoplastic cerebellar degeneration. |journal=Ann. Neurol. |volume=30 |issue= 5 |pages= 738 |year= 1992 |pmid= 1763903 |doi= 10.1002/ana.410300523 }}
*{{cite journal  | author=Fathallah-Shaykh H, Wolf S, Wong E, ''et al.'' |title=Cloning of a leucine-zipper protein recognized by the sera of patients with antibody-associated paraneoplastic cerebellar degeneration. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 8 |pages= 3451-4 |year= 1991 |pmid= 2014264 |doi=  }}
*{{cite journal  | vauthors=Sakai K, Mitchell DJ, Tsukamoto T, Steinman L |title=Isolation of a complementary DNA clone encoding an autoantigen recognized by an anti-neuronal cell antibody from a patient with paraneoplastic cerebellar degeneration. |journal=Ann. Neurol. |volume=28 |issue= 5 |pages= 692–8 |year= 1991 |pmid= 2260856 |doi= 10.1002/ana.410280515 }}
*{{cite journal  | author=Sakai K, Mitchell DJ, Tsukamoto T, Steinman L |title=Isolation of a complementary DNA clone encoding an autoantigen recognized by an anti-neuronal cell antibody from a patient with paraneoplastic cerebellar degeneration. |journal=Ann. Neurol. |volume=28 |issue= 5 |pages= 692-8 |year= 1991 |pmid= 2260856 |doi= 10.1002/ana.410280515 }}
*{{cite journal  | vauthors=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=10.1101/gr.6.9.791 }}
*{{cite journal  | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791-806 |year= 1997 |pmid= 8889548 |doi=  }}
*{{cite journal  | vauthors=Fletcher CF, Okano HJ, Gilbert DJ |title=Mouse chromosomal locations of nine genes encoding homologs of human paraneoplastic neurologic disorder antigens. |journal=Genomics |volume=45 |issue= 2 |pages= 313–9 |year= 1998 |pmid= 9344654 |doi= 10.1006/geno.1997.4925 |display-authors=etal}}
*{{cite journal  | author=Fletcher CF, Okano HJ, Gilbert DJ, ''et al.'' |title=Mouse chromosomal locations of nine genes encoding homologs of human paraneoplastic neurologic disorder antigens. |journal=Genomics |volume=45 |issue= 2 |pages= 313-9 |year= 1998 |pmid= 9344654 |doi= 10.1006/geno.1997.4925 }}
*{{cite journal  | vauthors=Takanaga H, Mukai H, Shibata H |title=PKN interacts with a paraneoplastic cerebellar degeneration-associated antigen, which is a potential transcription factor. |journal=Exp. Cell Res. |volume=241 |issue= 2 |pages= 363–72 |year= 1998 |pmid= 9637778 |doi= 10.1006/excr.1998.4060 |display-authors=etal}}
*{{cite journal  | author=Takanaga H, Mukai H, Shibata H, ''et al.'' |title=PKN interacts with a paraneoplastic cerebellar degeneration-associated antigen, which is a potential transcription factor. |journal=Exp. Cell Res. |volume=241 |issue= 2 |pages= 363-72 |year= 1998 |pmid= 9637778 |doi= 10.1006/excr.1998.4060 }}
*{{cite journal  | vauthors=Okano HJ, Park WY, Corradi JP, Darnell RB |title=The cytoplasmic Purkinje onconeural antigen cdr2 down-regulates c-Myc function: implications for neuronal and tumor cell survival. |journal=Genes Dev. |volume=13 |issue= 16 |pages= 2087–97 |year= 1999 |pmid= 10465786 |doi=10.1101/gad.13.16.2087  | pmc=316965 }}
*{{cite journal  | author=Okano HJ, Park WY, Corradi JP, Darnell RB |title=The cytoplasmic Purkinje onconeural antigen cdr2 down-regulates c-Myc function: implications for neuronal and tumor cell survival. |journal=Genes Dev. |volume=13 |issue= 16 |pages= 2087-97 |year= 1999 |pmid= 10465786 |doi=  }}
*{{cite journal  | vauthors=Sakai K, Shirakawa T, Li Y |title=Interaction of a paraneoplastic cerebellar degeneration-associated neuronal protein with the nuclear helix-loop-helix leucine zipper protein MRG X. |journal=Mol. Cell. Neurosci. |volume=19 |issue= 4 |pages= 477–84 |year= 2002 |pmid= 11988016 |doi= 10.1006/mcne.2001.1059 |display-authors=etal}}
*{{cite journal  | author=Sakai K, Shirakawa T, Li Y, ''et al.'' |title=Interaction of a paraneoplastic cerebellar degeneration-associated neuronal protein with the nuclear helix-loop-helix leucine zipper protein MRG X. |journal=Mol. Cell. Neurosci. |volume=19 |issue= 4 |pages= 477-84 |year= 2002 |pmid= 11988016 |doi= 10.1006/mcne.2001.1059 }}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Sutton IJ, Steele J, Savage CO |title=An interferon-gamma ELISPOT and immunohistochemical investigation of cytotoxic T lymphocyte-mediated tumour immunity in patients with paraneoplastic cerebellar degeneration and anti-Yo antibodies. |journal=J. Neuroimmunol. |volume=150 |issue= 1-2 |pages= 98–106 |year= 2004 |pmid= 15081253 |doi= 10.1016/j.jneuroim.2003.12.026 |display-authors=etal}}
*{{cite journal  | author=Sutton IJ, Steele J, Savage CO, ''et al.'' |title=An interferon-gamma ELISPOT and immunohistochemical investigation of cytotoxic T lymphocyte-mediated tumour immunity in patients with paraneoplastic cerebellar degeneration and anti-Yo antibodies. |journal=J. Neuroimmunol. |volume=150 |issue= 1-2 |pages= 98-106 |year= 2004 |pmid= 15081253 |doi= 10.1016/j.jneuroim.2003.12.026 }}
*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | vauthors=Balbo M, Barel M, Lottin-Divoux S |title=Infection of human B lymphoma cells by Mycoplasma fermentans induces interaction of its elongation factor with the intracytoplasmic domain of Epstein-Barr virus receptor (gp140, EBV/C3dR, CR2, CD21). |journal=FEMS Microbiol. Lett. |volume=249 |issue= 2 |pages= 359–66 |year= 2005 |pmid= 16054780 |doi= 10.1016/j.femsle.2005.06.052 |display-authors=etal}}
*{{cite journal  | author=Balbo M, Barel M, Lottin-Divoux S, ''et al.'' |title=Infection of human B lymphoma cells by Mycoplasma fermentans induces interaction of its elongation factor with the intracytoplasmic domain of Epstein-Barr virus receptor (gp140, EBV/C3dR, CR2, CD21). |journal=FEMS Microbiol. Lett. |volume=249 |issue= 2 |pages= 359-66 |year= 2005 |pmid= 16054780 |doi= 10.1016/j.femsle.2005.06.052 }}
}}
}}
{{refend}}
{{refend}}


{{protein-stub}}
==External links==
{{WikiDoc Sources}}
* {{UCSC genome browser|CDR2}}
* {{UCSC gene details|CDR2}}
 
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{{gene-16-stub}}

Latest revision as of 09:30, 30 August 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

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Ensembl

n/a

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UniProt

n/a

n/a

RefSeq (mRNA)

n/a

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RefSeq (protein)

n/a

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Cerebellar degeneration-related protein 2 is a protein that in humans is encoded by the CDR2 gene.[1][2]


See also

References

  1. ↑ Fathallah-Shaykh H, Wolf S, Wong E, Posner JB, Furneaux HM (May 1991). "Cloning of a leucine-zipper protein recognized by the sera of patients with antibody-associated paraneoplastic cerebellar degeneration". Proc Natl Acad Sci U S A. 88 (8): 3451–4. doi:10.1073/pnas.88.8.3451. PMC 51465. PMID 2014264.
  2. ↑ "Entrez Gene: CDR2 cerebellar degeneration-related protein 2, 62kDa".

Further reading

External links



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