CPSF2: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
m (Robot: Automated text replacement (-{{WikiDoc Cardiology Network Infobox}} +, -<references /> +{{reflist|2}}, -{{reflist}} +{{reflist|2}}))
 
m (Bot: HTTP→HTTPS)
Line 1: Line 1:
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Underlinked|date=May 2016}}
{{PBB_Controls
{{Infobox_gene}}
| update_page = yes
'''Cleavage and polyadenylation specificity factor subunit 2''' is a [[protein]] that in humans is encoded by the ''CPSF2'' [[gene]].<ref name="pmid7969155">{{cite journal | vauthors = Jenny A, Hauri HP, Keller W | title = Characterization of cleavage and polyadenylation specificity factor and cloning of its 100-kilodalton subunit | journal = Mol Cell Biol | volume = 14 | issue = 12 | pages = 8183–90 |date=Dec 1994 | pmid = 7969155 | pmc = 359357 | doi = }}</ref><ref name="pmid11124543">{{cite journal | vauthors = Samiotaki M, Balatsos NA, Courtis N, Tsiapalis CM | title = Assignment of the 100-kDa subunit of cleavage and polyadenylation specificity factor (CPSF2) to human chromosome 14q31.3 by radiation hybrid mapping | journal = Cytogenet Cell Genet | volume = 90 | issue = 3–4 | pages = 328–9 |date=Jan 2001 | pmid = 11124543 | pmc = | doi =10.1159/000056798 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CPSF2 cleavage and polyadenylation specific factor 2, 100kDa| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=53981| accessdate = }}</ref>
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
 
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Cleavage and polyadenylation specific factor 2, 100kDa
| HGNCid = 2325
| Symbol = CPSF2
| AltSymbols =; CPSF100; KIAA1367
| OMIM = 606028
| ECnumber = 
| Homologene = 6460
| MGIid = 1861601
| GeneAtlas_image1 = PBB_GE_CPSF2_gnf1h01366_at_tn.png
| GeneAtlas_image2 = PBB_GE_CPSF2_gnf1h06234_s_at_tn.png
| Function = {{GNF_GO|id=GO:0003723 |text = RNA binding}} {{GNF_GO|id=GO:0016787 |text = hydrolase activity}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006397 |text = mRNA processing}}  
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 53981
    | Hs_Ensembl = ENSG00000165934
    | Hs_RefseqProtein = NP_059133
    | Hs_RefseqmRNA = NM_017437
    | Hs_GenLoc_db =
    | Hs_GenLoc_chr = 14
    | Hs_GenLoc_start = 91658082
    | Hs_GenLoc_end = 91700296
    | Hs_Uniprot = Q9P2I0
    | Mm_EntrezGene = 51786
    | Mm_Ensembl = ENSMUSG00000041781
    | Mm_RefseqmRNA = NM_016856
    | Mm_RefseqProtein = NP_058552
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 12
    | Mm_GenLoc_start = 102377049
    | Mm_GenLoc_end = 102406579
    | Mm_Uniprot = Q3UGU6
  }}
}}
'''Cleavage and polyadenylation specific factor 2, 100kDa''', also known as '''CPSF2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CPSF2 cleavage and polyadenylation specific factor 2, 100kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=53981| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
Line 56: Line 10:


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==External links==
* {{UCSC gene info|CPSF2}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Murthy KG, Manley JL |title=The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation. |journal=Genes Dev. |volume=9 |issue= 21 |pages= 2672-83 |year= 1995 |pmid= 7590244 |doi=  }}
*{{cite journal  | vauthors=Murthy KG, Manley JL |title=The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation. |journal=Genes Dev. |volume=9 |issue= 21 |pages= 2672–83 |year= 1995 |pmid= 7590244 |doi=10.1101/gad.9.21.2672 }}
*{{cite journal  | author=Jenny A, Hauri HP, Keller W |title=Characterization of cleavage and polyadenylation specificity factor and cloning of its 100-kilodalton subunit. |journal=Mol. Cell. Biol. |volume=14 |issue= 12 |pages= 8183-90 |year= 1994 |pmid= 7969155 |doi=  }}
*{{cite journal  | vauthors=Thuresson AC, Aström J, Aström A |title=Multiple forms of poly(A) polymerases in human cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 3 |pages= 979–83 |year= 1994 |pmid= 8302877 |doi=10.1073/pnas.91.3.979 | pmc=521437  |display-authors=etal}}
*{{cite journal  | author=Thuresson AC, Aström J, Aström A, ''et al.'' |title=Multiple forms of poly(A) polymerases in human cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 3 |pages= 979-83 |year= 1994 |pmid= 8302877 |doi=  }}
*{{cite journal  | vauthors=Bienroth S, Keller W, Wahle E |title=Assembly of a processive messenger RNA polyadenylation complex. |journal=EMBO J. |volume=12 |issue= 2 |pages= 585–94 |year= 1993 |pmid= 8440247 |doi= | pmc=413241 }}
*{{cite journal  | author=Bienroth S, Keller W, Wahle E |title=Assembly of a processive messenger RNA polyadenylation complex. |journal=EMBO J. |volume=12 |issue= 2 |pages= 585-94 |year= 1993 |pmid= 8440247 |doi=  }}
*{{cite journal  | vauthors=Schul W, Groenhout B, Koberna K |title=The RNA 3' cleavage factors CstF 64 kDa and CPSF 100 kDa are concentrated in nuclear domains closely associated with coiled bodies and newly synthesized RNA. |journal=EMBO J. |volume=15 |issue= 11 |pages= 2883–92 |year= 1996 |pmid= 8654386 |doi=  | pmc=450226  |display-authors=etal}}
*{{cite journal  | author=Schul W, Groenhout B, Koberna K, ''et al.'' |title=The RNA 3' cleavage factors CstF 64 kDa and CPSF 100 kDa are concentrated in nuclear domains closely associated with coiled bodies and newly synthesized RNA. |journal=EMBO J. |volume=15 |issue= 11 |pages= 2883-92 |year= 1996 |pmid= 8654386 |doi= }}
*{{cite journal  | vauthors=McCracken S, Fong N, Yankulov K |title=The C-terminal domain of RNA polymerase II couples mRNA processing to transcription. |journal=Nature |volume=385 |issue= 6614 |pages= 357–61 |year= 1997 |pmid= 9002523 |doi= 10.1038/385357a0 |display-authors=etal}}
*{{cite journal  | author=McCracken S, Fong N, Yankulov K, ''et al.'' |title=The C-terminal domain of RNA polymerase II couples mRNA processing to transcription. |journal=Nature |volume=385 |issue= 6614 |pages= 357-61 |year= 1997 |pmid= 9002523 |doi= 10.1038/385357a0 }}
*{{cite journal  | vauthors=Takagaki Y, Manley JL |title=Complex protein interactions within the human polyadenylation machinery identify a novel component. |journal=Mol. Cell. Biol. |volume=20 |issue= 5 |pages= 1515–25 |year= 2000 |pmid= 10669729 |doi=10.1128/MCB.20.5.1515-1525.2000  | pmc=85326  }}
*{{cite journal  | author=Takagaki Y, Manley JL |title=Complex protein interactions within the human polyadenylation machinery identify a novel component. |journal=Mol. Cell. Biol. |volume=20 |issue= 5 |pages= 1515-25 |year= 2000 |pmid= 10669729 |doi=  }}
*{{cite journal  | vauthors=Nagase T, Kikuno R, Ishikawa KI |title=Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=7 |issue= 1 |pages= 65–73 |year= 2000 |pmid= 10718198 |doi=10.1093/dnares/7.1.65 |display-authors=etal}}
*{{cite journal  | author=Nagase T, Kikuno R, Ishikawa KI, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=7 |issue= 1 |pages= 65-73 |year= 2000 |pmid= 10718198 |doi=  }}
*{{cite journal  | vauthors=Monsalve M, Wu Z, Adelmant G |title=Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. |journal=Mol. Cell |volume=6 |issue= 2 |pages= 307–16 |year= 2000 |pmid= 10983978 |doi=10.1016/S1097-2765(00)00031-9 |display-authors=etal}}
*{{cite journal  | author=Monsalve M, Wu Z, Adelmant G, ''et al.'' |title=Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. |journal=Mol. Cell |volume=6 |issue= 2 |pages= 307-16 |year= 2000 |pmid= 10983978 |doi=  }}
*{{cite journal  | vauthors=de Vries H, Rüegsegger U, Hübner W |title=Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors. |journal=EMBO J. |volume=19 |issue= 21 |pages= 5895–904 |year= 2000 |pmid= 11060040 |doi= 10.1093/emboj/19.21.5895 | pmc=305781 |display-authors=etal}}
*{{cite journal  | author=de Vries H, Rüegsegger U, Hübner W, ''et al.'' |title=Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors. |journal=EMBO J. |volume=19 |issue= 21 |pages= 5895-904 |year= 2000 |pmid= 11060040 |doi= 10.1093/emboj/19.21.5895 }}
*{{cite journal  | vauthors=Hodgman R, Tay J, Mendez R, Richter JD |title=CPEB phosphorylation and cytoplasmic polyadenylation are catalyzed by the kinase IAK1/Eg2 in maturing mouse oocytes. |journal=Development |volume=128 |issue= 14 |pages= 2815–22 |year= 2001 |pmid= 11526086 |doi= }}
*{{cite journal  | author=Samiotaki M, Balatsos NA, Courtis N, Tsiapalis CM |title=Assignment of the 100-kDa subunit of cleavage and polyadenylation specificity factor (CPSF2) to human chromosome 14q31.3 by radiation hybrid mapping. |journal=Cytogenet. Cell Genet. |volume=90 |issue= 3-4 |pages= 328-9 |year= 2001 |pmid= 11124543 |doi= }}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Hodgman R, Tay J, Mendez R, Richter JD |title=CPEB phosphorylation and cytoplasmic polyadenylation are catalyzed by the kinase IAK1/Eg2 in maturing mouse oocytes. |journal=Development |volume=128 |issue= 14 |pages= 2815-22 |year= 2001 |pmid= 11526086 |doi= }}
*{{cite journal  | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Kaufmann I, Martin G, Friedlein A |title=Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase. |journal=EMBO J. |volume=23 |issue= 3 |pages= 616–26 |year= 2005 |pmid= 14749727 |doi= 10.1038/sj.emboj.7600070  | pmc=1271804 |display-authors=etal}}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | vauthors=Beausoleil SA, Jedrychowski M, Schwartz D |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101  | pmc=514446 |display-authors=etal}}
*{{cite journal  | author=Kaufmann I, Martin G, Friedlein A, ''et al.'' |title=Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase. |journal=EMBO J. |volume=23 |issue= 3 |pages= 616-26 |year= 2005 |pmid= 14749727 |doi= 10.1038/sj.emboj.7600070 }}
*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 |display-authors=etal}}
*{{cite journal  | author=Beausoleil SA, Jedrychowski M, Schwartz D, ''et al.'' |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130-5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 }}
*{{cite journal  | vauthors=Kimura K, Wakamatsu A, Suzuki Y |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406  | pmc=1356129 |display-authors=etal}}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | vauthors=Olsen JV, Blagoev B, Gnad F |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 |display-authors=etal}}
*{{cite journal  | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
*{{cite journal  | vauthors=Ewing RM, Chu P, Elisma F |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= 1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 | pmc=1847948 |display-authors=etal}}
*{{cite journal  | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal | author=Ewing RM, Chu P, Elisma F, ''et al.'' |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue=  |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 }}
}}
}}
{{refend}}
{{refend}}


{{protein-stub}}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{WikiDoc Sources}}
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
 
 
{{gene-14-stub}}

Revision as of 10:00, 30 August 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Cleavage and polyadenylation specificity factor subunit 2 is a protein that in humans is encoded by the CPSF2 gene.[1][2][3]


References

  1. ↑ Jenny A, Hauri HP, Keller W (Dec 1994). "Characterization of cleavage and polyadenylation specificity factor and cloning of its 100-kilodalton subunit". Mol Cell Biol. 14 (12): 8183–90. PMC 359357. PMID 7969155.
  2. ↑ Samiotaki M, Balatsos NA, Courtis N, Tsiapalis CM (Jan 2001). "Assignment of the 100-kDa subunit of cleavage and polyadenylation specificity factor (CPSF2) to human chromosome 14q31.3 by radiation hybrid mapping". Cytogenet Cell Genet. 90 (3–4): 328–9. doi:10.1159/000056798. PMID 11124543.
  3. ↑ "Entrez Gene: CPSF2 cleavage and polyadenylation specific factor 2, 100kDa".

External links

Further reading



Retrieved from "https://www.wikidoc.org/index.php?title=CPSF2&oldid=1416532"