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{{Underlinked|date=May 2016}}
{{PBB_Controls
{{Infobox_gene}}
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'''Cysteine-rich secretory protein 3''' is a [[cysteine-rich secretory protein]] that in humans is encoded by the ''CRISP3'' [[gene]].<ref name="pmid8665901">{{cite journal | vauthors = Kratzschmar J, Haendler B, Eberspaecher U, Roosterman D, Donner P, Schleuning WD | title = The human cysteine-rich secretory protein (CRISP) family. Primary structure and tissue distribution of CRISP-1, CRISP-2 and CRISP-3 | journal = Eur J Biochem | volume = 236 | issue = 3 | pages = 827–36 |date=Aug 1996 | pmid = 8665901 | pmc =  | doi =10.1111/j.1432-1033.1996.t01-1-00827.x }}</ref><ref name="pmid12223513">{{cite journal | vauthors = Udby L, Calafat J, Sorensen OE, Borregaard N, Kjeldsen L | title = Identification of human cysteine-rich secretory protein 3 (CRISP-3) as a matrix protein in a subset of peroxidase-negative granules of neutrophils and in the granules of eosinophils | journal = J Leukoc Biol | volume = 72 | issue = 3 | pages = 462–9 |date=Sep 2002 | pmid = 12223513 | pmc =  | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CRISP3 cysteine-rich secretory protein 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10321| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Cysteine-rich secretory protein 3
| HGNCid = 16904
| Symbol = CRISP3
| AltSymbols =; CRS3; Aeg2; CRISP-3; MGC126588; SGP28; dJ442L6.3
| OMIM =
| ECnumber =
| Homologene = 50654
| MGIid = 102553
  | GeneAtlas_image1 = PBB_GE_CRISP3_207802_at_tn.png
  | Function = {{GNF_GO|id=GO:0003674 |text = molecular_function}}  
| Component = {{GNF_GO|id=GO:0005576 |text = extracellular region}} {{GNF_GO|id=GO:0005578 |text = proteinaceous extracellular matrix}} {{GNF_GO|id=GO:0042581 |text = specific granule}}
| Process = {{GNF_GO|id=GO:0007283 |text = spermatogenesis}} {{GNF_GO|id=GO:0009566 |text = fertilization}} {{GNF_GO|id=GO:0016337 |text = cell-cell adhesion}} {{GNF_GO|id=GO:0045087 |text = innate immune response}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 10321
    | Hs_Ensembl = ENSG00000096006
    | Hs_RefseqProtein = NP_006052
    | Hs_RefseqmRNA = NM_006061
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 6
    | Hs_GenLoc_start = 49803056
    | Hs_GenLoc_end = 49820040
    | Hs_Uniprot = P54108
    | Mm_EntrezGene = 11571
    | Mm_Ensembl = ENSMUSG00000025431
    | Mm_RefseqmRNA = NM_009638
    | Mm_RefseqProtein = NP_033768
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 17
    | Mm_GenLoc_start = 39757236
    | Mm_GenLoc_end = 39782691
    | Mm_Uniprot = Q545H0
  }}
}}
'''Cysteine-rich secretory protein 3''', also known as '''CRISP3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CRISP3 cysteine-rich secretory protein 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10321| accessdate = }}</ref>
 
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==References==
{{reflist}}


==References==
{{reflist|2}}
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal  | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
*{{cite journal  | author=Kjeldsen L, Cowland JB, Johnsen AH, Borregaard N |title=SGP28, a novel matrix glycoprotein in specific granules of human neutrophils with similarity to a human testis-specific gene product and a rodent sperm-coating glycoprotein. |journal=FEBS Lett. |volume=380 |issue= 3 |pages= 246-50 |year= 1996 |pmid= 8601434 |doi=  }}
*{{cite journal  | vauthors=Kjeldsen L, Cowland JB, Johnsen AH, Borregaard N |title=SGP28, a novel matrix glycoprotein in specific granules of human neutrophils with similarity to a human testis-specific gene product and a rodent sperm-coating glycoprotein. |journal=FEBS Lett. |volume=380 |issue= 3 |pages= 246–50 |year= 1996 |pmid= 8601434 |doi=10.1016/0014-5793(96)00030-0 }}
*{{cite journal  | author=Krätzschmar J, Haendler B, Eberspaecher U, ''et al.'' |title=The human cysteine-rich secretory protein (CRISP) family. Primary structure and tissue distribution of CRISP-1, CRISP-2 and CRISP-3. |journal=Eur. J. Biochem. |volume=236 |issue= 3 |pages= 827-36 |year= 1996 |pmid= 8665901 |doi=  }}
*{{cite journal  | vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 |display-authors=etal}}
*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
*{{cite journal  | vauthors=Cowland JB, Borregaard N |title=The individual regulation of granule protein mRNA levels during neutrophil maturation explains the heterogeneity of neutrophil granules. |journal=J. Leukoc. Biol. |volume=66 |issue= 6 |pages= 989–95 |year= 2000 |pmid= 10614782 |doi=  }}
*{{cite journal  | author=Cowland JB, Borregaard N |title=The individual regulation of granule protein mRNA levels during neutrophil maturation explains the heterogeneity of neutrophil granules. |journal=J. Leukoc. Biol. |volume=66 |issue= 6 |pages= 989-95 |year= 2000 |pmid= 10614782 |doi=  }}
*{{cite journal  | vauthors=Friess H, Ding J, Kleeff J |title=Identification of disease-specific genes in chronic pancreatitis using DNA array technology. |journal=Ann. Surg. |volume=234 |issue= 6 |pages= 769–78; discussion 778–9 |year= 2002 |pmid= 11729383 |doi=10.1097/00000658-200112000-00008 | pmc=1422136  |display-authors=etal}}
*{{cite journal  | author=Friess H, Ding J, Kleeff J, ''et al.'' |title=Identification of disease-specific genes in chronic pancreatitis using DNA array technology. |journal=Ann. Surg. |volume=234 |issue= 6 |pages= 769-78; discussion 778-9 |year= 2002 |pmid= 11729383 |doi= }}
*{{cite journal  | vauthors=Udby L, Cowland JB, Johnsen AH |title=An ELISA for SGP28/CRISP-3, a cysteine-rich secretory protein in human neutrophils, plasma, and exocrine secretions. |journal=J. Immunol. Methods |volume=263 |issue= 1-2 |pages= 43–55 |year= 2002 |pmid= 12009203 |doi=10.1016/S0022-1759(02)00033-9  |display-authors=etal}}
*{{cite journal  | author=Udby L, Cowland JB, Johnsen AH, ''et al.'' |title=An ELISA for SGP28/CRISP-3, a cysteine-rich secretory protein in human neutrophils, plasma, and exocrine secretions. |journal=J. Immunol. Methods |volume=263 |issue= 1-2 |pages= 43-55 |year= 2002 |pmid= 12009203 |doi=  }}
*{{cite journal  | vauthors=Kosari F, Asmann YW, Cheville JC, Vasmatzis G |title=Cysteine-rich secretory protein-3: a potential biomarker for prostate cancer. |journal=Cancer Epidemiol. Biomarkers Prev. |volume=11 |issue= 11 |pages= 1419–26 |year= 2003 |pmid= 12433721 |doi=  }}
*{{cite journal  | author=Udby L, Calafat J, Sørensen OE, ''et al.'' |title=Identification of human cysteine-rich secretory protein 3 (CRISP-3) as a matrix protein in a subset of peroxidase-negative granules of neutrophils and in the granules of eosinophils. |journal=J. Leukoc. Biol. |volume=72 |issue= 3 |pages= 462-9 |year= 2002 |pmid= 12223513 |doi=  }}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Kosari F, Asmann YW, Cheville JC, Vasmatzis G |title=Cysteine-rich secretory protein-3: a potential biomarker for prostate cancer. |journal=Cancer Epidemiol. Biomarkers Prev. |volume=11 |issue= 11 |pages= 1419-26 |year= 2003 |pmid= 12433721 |doi=  }}
*{{cite journal  | vauthors=Liao Q, Kleeff J, Xiao Y |title=Preferential expression of cystein-rich secretory protein-3 (CRISP-3) in chronic pancreatitis. |journal=Histol. Histopathol. |volume=18 |issue= 2 |pages= 425–33 |year= 2003 |pmid= 12647793 |doi=  |display-authors=etal}}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Mungall AJ, Palmer SA, Sims SK |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055 |display-authors=etal}}
*{{cite journal  | author=Liao Q, Kleeff J, Xiao Y, ''et al.'' |title=Preferential expression of cystein-rich secretory protein-3 (CRISP-3) in chronic pancreatitis. |journal=Histol. Histopathol. |volume=18 |issue= 2 |pages= 425-33 |year= 2003 |pmid= 12647793 |doi= }}
*{{cite journal  | vauthors=Udby L, Sørensen OE, Pass J |title=Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma. |journal=Biochemistry |volume=43 |issue= 40 |pages= 12877–86 |year= 2004 |pmid= 15461460 |doi= 10.1021/bi048823e |display-authors=etal}}
*{{cite journal  | author=Mungall AJ, Palmer SA, Sims SK, ''et al.'' |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805-11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055 }}
*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 |display-authors=etal}}
*{{cite journal  | author=Udby L, Sørensen OE, Pass J, ''et al.'' |title=Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma. |journal=Biochemistry |volume=43 |issue= 40 |pages= 12877-86 |year= 2004 |pmid= 15461460 |doi= 10.1021/bi048823e }}
*{{cite journal  | vauthors=Udby L, Bjartell A, Malm J |title=Characterization and localization of cysteine-rich secretory protein 3 (CRISP-3) in the human male reproductive tract. |journal=J. Androl. |volume=26 |issue= 3 |pages= 333–42 |year= 2005 |pmid= 15867000 |doi= 10.2164/jandrol.04132 |display-authors=etal}}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | vauthors=Udby L, Lundwall A, Johnsen AH |title=beta-Microseminoprotein binds CRISP-3 in human seminal plasma. |journal=Biochem. Biophys. Res. Commun. |volume=333 |issue= 2 |pages= 555–61 |year= 2005 |pmid= 15950934 |doi= 10.1016/j.bbrc.2005.05.139  | pmc=1939934 |display-authors=etal}}
*{{cite journal  | author=Udby L, Bjartell A, Malm J, ''et al.'' |title=Characterization and localization of cysteine-rich secretory protein 3 (CRISP-3) in the human male reproductive tract. |journal=J. Androl. |volume=26 |issue= 3 |pages= 333-42 |year= 2005 |pmid= 15867000 |doi= 10.2164/jandrol.04132 }}
*{{cite journal  | vauthors=Bjartell A, Johansson R, Björk T |title=Immunohistochemical detection of cysteine-rich secretory protein 3 in tissue and in serum from men with cancer or benign enlargement of the prostate gland. |journal=Prostate |volume=66 |issue= 6 |pages= 591–603 |year= 2006 |pmid= 16388501 |doi= 10.1002/pros.20342 |display-authors=etal}}
*{{cite journal  | author=Udby L, Lundwall A, Johnsen AH, ''et al.'' |title=beta-Microseminoprotein binds CRISP-3 in human seminal plasma. |journal=Biochem. Biophys. Res. Commun. |volume=333 |issue= 2 |pages= 555-61 |year= 2005 |pmid= 15950934 |doi= 10.1016/j.bbrc.2005.05.139 }}
*{{cite journal  | vauthors=Bjartell AS, Al-Ahmadie H, Serio AM |title=Association of cysteine-rich secretory protein 3 and beta-microseminoprotein with outcome after radical prostatectomy. |journal=Clin. Cancer Res. |volume=13 |issue= 14 |pages= 4130–8 |year= 2007 |pmid= 17634540 |doi= 10.1158/1078-0432.CCR-06-3031  | pmc=2660867 |display-authors=etal}}
*{{cite journal  | author=Bjartell A, Johansson R, Björk T, ''et al.'' |title=Immunohistochemical detection of cysteine-rich secretory protein 3 in tissue and in serum from men with cancer or benign enlargement of the prostate gland. |journal=Prostate |volume=66 |issue= 6 |pages= 591-603 |year= 2006 |pmid= 16388501 |doi= 10.1002/pros.20342 }}
*{{cite journal  | vauthors=Laine M, Porola P, Udby L |title=Low salivary dehydroepiandrosterone and androgen-regulated cysteine-rich secretory protein 3 levels in Sjögren's syndrome. |journal=Arthritis Rheum. |volume=56 |issue= 8 |pages= 2575–84 |year= 2007 |pmid= 17665393 |doi= 10.1002/art.22828 |display-authors=etal}}
*{{cite journal  | author=Bjartell AS, Al-Ahmadie H, Serio AM, ''et al.'' |title=Association of cysteine-rich secretory protein 3 and beta-microseminoprotein with outcome after radical prostatectomy. |journal=Clin. Cancer Res. |volume=13 |issue= 14 |pages= 4130-8 |year= 2007 |pmid= 17634540 |doi= 10.1158/1078-0432.CCR-06-3031 }}
*{{cite journal  | author=Laine M, Porola P, Udby L, ''et al.'' |title=Low salivary dehydroepiandrosterone and androgen-regulated cysteine-rich secretory protein 3 levels in Sjögren's syndrome. |journal=Arthritis Rheum. |volume=56 |issue= 8 |pages= 2575-84 |year= 2007 |pmid= 17665393 |doi= 10.1002/art.22828 }}
}}
}}
{{refend}}
{{refend}}


{{protein-stub}}
==External links==
{{WikiDoc Sources}}
* {{UCSC genome browser|CRISP3}}
* {{UCSC gene details|CRISP3}}
 
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Revision as of 10:03, 30 August 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Cysteine-rich secretory protein 3 is a cysteine-rich secretory protein that in humans is encoded by the CRISP3 gene.[1][2][3]

References

  1. ↑ Kratzschmar J, Haendler B, Eberspaecher U, Roosterman D, Donner P, Schleuning WD (Aug 1996). "The human cysteine-rich secretory protein (CRISP) family. Primary structure and tissue distribution of CRISP-1, CRISP-2 and CRISP-3". Eur J Biochem. 236 (3): 827–36. doi:10.1111/j.1432-1033.1996.t01-1-00827.x. PMID 8665901.
  2. ↑ Udby L, Calafat J, Sorensen OE, Borregaard N, Kjeldsen L (Sep 2002). "Identification of human cysteine-rich secretory protein 3 (CRISP-3) as a matrix protein in a subset of peroxidase-negative granules of neutrophils and in the granules of eosinophils". J Leukoc Biol. 72 (3): 462–9. PMID 12223513.
  3. ↑ "Entrez Gene: CRISP3 cysteine-rich secretory protein 3".

Further reading

External links



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