CSN1S1: Difference between revisions

VALUE_ERROR (nil)
Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

VisualWikitext

Revision as of 19:37, 8 November 2017

Alpha-S1-casein is a protein that in humans is encoded by the CSN1S1 gene.^[1]^[2]^[3]

Interactions

CSN1S1 has been shown to interact with SAP130.^[4]

References

↑ Fujiwara Y, Miwa M, Nogami M, Okumura K, Nobori T, Suzuki T, Ueda M (Mar 1997). "Genomic organization and chromosomal localization of the human casein gene family". Hum Genet. 99 (3): 368–73. doi:10.1007/s004390050374. PMID 9050925.
↑ Johnsen LB, Rasmussen LK, Petersen TE, Berglund L (Aug 1995). "Characterization of three types of human alpha s1-casein mRNA transcripts". Biochem J. 309. ( Pt 1): 237–42. PMC 1135825. PMID 7619062.
↑ "Entrez Gene: CSN1S1 casein alpha s1".
↑ Menon, Suchithra; Tsuge Tomohiko; Dohmae Naoshi; Takio Koji; Wei Ning (2008). "Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome". BMC Biochem. England. 9: 1. doi:10.1186/1471-2091-9-1. PMC 2265268. PMID 18173839.

External links

Human CSN1S1 genome location and CSN1S1 gene details page in the UCSC Genome Browser.

Takahashi M, Tomizawa K, Sato K, et al. (1995). "A novel tau-tubulin kinase from bovine brain". FEBS Lett. 372 (1): 59–64. doi:10.1016/0014-5793(95)00955-9. PMID 7556643.
Creasy CL, Chernoff J (1995). "Cloning and characterization of a human protein kinase with homology to Ste20". J. Biol. Chem. 270 (37): 21695–700. doi:10.1074/jbc.270.37.21695. PMID 7665586.
Chen CS, Bejcek BE, Kersey JH (1995). "A mapping study of 13 genes on human chromosome bands 4q11→q25". Cytogenet. Cell Genet. 69 (3–4): 260–5. doi:10.1159/000133976. PMID 7698025.
Cavaletto M, Cantisani A, Giuffrida G, et al. (1994). "Human alpha S1-casein like protein: purification and N-terminal sequence determination". Biol. Chem. Hoppe-Seyler. 375 (2): 149–51. doi:10.1515/bchm3.1994.375.2.149. PMID 8192860.
Murakami K, Lagarde M, Yuki Y (1999). "Identification of minor proteins of human colostrum and mature milk by two-dimensional electrophoresis". Electrophoresis. 19 (14): 2521–7. doi:10.1002/elps.1150191427. PMID 9820977.
Silljé HH, Takahashi K, Tanaka K, et al. (1999). "Mammalian homologues of the plant Tousled gene code for cell-cycle-regulated kinases with maximal activities linked to ongoing DNA replication". EMBO J. 18 (20): 5691–702. doi:10.1093/emboj/18.20.5691. PMC 1171636. PMID 10523312.
Menegay HJ, Myers MP, Moeslein FM, Landreth GE (2000). "Biochemical characterization and localization of the dual specificity kinase CLK1". J. Cell Sci. 113. ( Pt 18): 3241–53. PMID 10954422.
Gray CW, Ward RV, Karran E, et al. (2000). "Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response". Eur. J. Biochem. 267 (18): 5699–710. doi:10.1046/j.1432-1327.2000.01589.x. PMID 10971580.
Harrington JJ, Sherf B, Rundlett S, et al. (2001). "Creation of genome-wide protein expression libraries using random activation of gene expression". Nat. Biotechnol. 19 (5): 440–5. doi:10.1038/88107. PMID 11329013.
Kashiwaba M, Katsura K, Ohnishi M, et al. (2003). "A novel protein phosphatase 2C family member (PP2Czeta) is able to associate with ubiquitin conjugating enzyme 9". FEBS Lett. 538 (1–3): 197–202. doi:10.1016/S0014-5793(03)00153-4. PMID 12633878.
Xu K, Ling MT, Wang X, Wong YC (2007). "Evidence of a novel biomarker, alphas1-Casein, a milk protein, in benign prostate hyperplasia". Prostate Cancer Prostatic Dis. 9 (3): 293–7. doi:10.1038/sj.pcan.4500872. PMID 16683014.

This article on a gene on human chromosome 4 is a stub. You can help Wikipedia by expanding it.

[pmid9050925-1] Fujiwara Y, Miwa M, Nogami M, Okumura K, Nobori T, Suzuki T, Ueda M (Mar 1997). "Genomic organization and chromosomal localization of the human casein gene family". Hum Genet. 99 (3): 368–73. doi:10.1007/s004390050374. PMID 9050925.

[pmid7619062-2] Johnsen LB, Rasmussen LK, Petersen TE, Berglund L (Aug 1995). "Characterization of three types of human alpha s1-casein mRNA transcripts". Biochem J. 309. ( Pt 1): 237–42. PMC 1135825. PMID 7619062.

[entrez-3] "Entrez Gene: CSN1S1 casein alpha s1".

[pmid18173839-4] Menon, Suchithra; Tsuge Tomohiko; Dohmae Naoshi; Takio Koji; Wei Ning (2008). "Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome". BMC Biochem. England. 9: 1. doi:10.1186/1471-2091-9-1. PMC 2265268. PMID 18173839.

[1]

[2]

[3]

[4]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''Alpha-S1-casein''' is a [[protein]] that in humans is encoded by the ''CSN1S1'' [[gene]].<ref name="pmid9050925">{{cite journal | vauthors = Fujiwara Y, Miwa M, Nogami M, Okumura K, Nobori T, Suzuki T, Ueda M | title = Genomic organization and chromosomal localization of the human casein gene family | journal = Hum Genet | volume = 99 | issue = 3 | pages = 368–73 |date=Mar 1997 | pmid = 9050925 | pmc =  | doi =10.1007/s004390050374  }}</ref><ref name="pmid7619062">{{cite journal | vauthors = Johnsen LB, Rasmussen LK, Petersen TE, Berglund L | title = Characterization of three types of human alpha s1-casein mRNA transcripts | series = 309 | journal = Biochem J | volume = ( Pt 1) | issue =  | pages = 237–42 |date=Aug 1995 | pmid = 7619062 | pmc = 1135825 | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CSN1S1 casein alpha s1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1446| accessdate = }}</ref>
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Casein alpha s1
- | HGNCid = 2445
- | Symbol = CSN1S1
- | AltSymbols =; CASA; CSN1; MGC149368
- | OMIM = 115450
- | ECnumber =
- | Homologene = 48054
- | MGIid =
-  | GeneAtlas_image1 = PBB_GE_CSN1S1_208350_at_tn.png
-  | Function = {{GNF_GO|id=GO:0005215 |text = transporter activity}}
- | Component = {{GNF_GO|id=GO:0005576 |text = extracellular region}}
- | Process = {{GNF_GO|id=GO:0006810 |text = transport}} {{GNF_GO|id=GO:0007586 |text = digestion}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 1446
-    | Hs_Ensembl = ENSG00000126545
-    | Hs_RefseqProtein = NP_001020275
-    | Hs_RefseqmRNA = NM_001025104
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 4
-    | Hs_GenLoc_start = 70831388
-    | Hs_GenLoc_end = 70846877
-    | Hs_Uniprot = P47710
-    | Mm_EntrezGene =
-    | Mm_Ensembl =
-    | Mm_RefseqmRNA =
-    | Mm_RefseqProtein =
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr =
-    | Mm_GenLoc_start =
-    | Mm_GenLoc_end =
-    | Mm_Uniprot =
-  }}
-}}
-'''Casein alpha s1''', also known as '''CSN1S1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CSN1S1 casein alpha s1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1446| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
 {{PBB_Summary
@@ Line 53: / Line 6: @@
 | summary_text =
 }}
+==Interactions==
+CSN1S1 has been shown to [[Protein-protein interaction|interact]] with [[SAP130]].<ref name=pmid18173839>{{cite journal |last=Menon |first=Suchithra |author2=Tsuge Tomohiko |author3=Dohmae Naoshi |author4=Takio Koji |author5=Wei Ning  |year=2008|title=Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome |journal=BMC Biochem. |volume=9|pages=1 |publisher= |location = England| issn = | pmid = 18173839 |doi = 10.1186/1471-2091-9-1 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=2265268 }}</ref>
 ==References==
-{{reflist|2}}
+{{reflist}}
+==External links==
+* {{UCSC gene info|CSN1S1}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Takahashi M, Tomizawa K, Sato K, ''et al.'' |title=A novel tau-tubulin kinase from bovine brain. |journal=FEBS Lett. |volume=372 |issue= 1 |pages= 59-64 |year= 1995 |pmid= 7556643 |doi=  }}
+*{{cite journal  | vauthors=Takahashi M, Tomizawa K, Sato K |title=A novel tau-tubulin kinase from bovine brain. |journal=FEBS Lett. |volume=372 |issue= 1 |pages= 59–64 |year= 1995 |pmid= 7556643 |doi=10.1016/0014-5793(95)00955-9  |display-authors=etal}}
-*{{cite journal  | author=Johnsen LB, Rasmussen LK, Petersen TE, Berglund L |title=Characterization of three types of human alpha s1-casein mRNA transcripts. |journal=Biochem. J. |volume=309 ( Pt 1) |issue=  |pages= 237-42 |year= 1995 |pmid= 7619062 |doi=  }}
+*{{cite journal  | vauthors=Creasy CL, Chernoff J |title=Cloning and characterization of a human protein kinase with homology to Ste20. |journal=J. Biol. Chem. |volume=270 |issue= 37 |pages= 21695–700 |year= 1995 |pmid= 7665586 |doi=10.1074/jbc.270.37.21695  }}
-*{{cite journal  | author=Creasy CL, Chernoff J |title=Cloning and characterization of a human protein kinase with homology to Ste20. |journal=J. Biol. Chem. |volume=270 |issue= 37 |pages= 21695-700 |year= 1995 |pmid= 7665586 |doi=  }}
+*{{cite journal  | vauthors=Chen CS, Bejcek BE, Kersey JH |title=A mapping study of 13 genes on human chromosome bands 4q11→q25. |journal=Cytogenet. Cell Genet. |volume=69 |issue= 3-4 |pages= 260–5 |year= 1995 |pmid= 7698025 |doi=10.1159/000133976  }}
-*{{cite journal  | author=Chen CS, Bejcek BE, Kersey JH |title=A mapping study of 13 genes on human chromosome bands 4q11-->q25. |journal=Cytogenet. Cell Genet. |volume=69 |issue= 3-4 |pages= 260-5 |year= 1995 |pmid= 7698025 |doi=  }}
+*{{cite journal  | vauthors=Cavaletto M, Cantisani A, Giuffrida G |title=Human alpha S1-casein like protein: purification and N-terminal sequence determination. |journal=Biol. Chem. Hoppe-Seyler |volume=375 |issue= 2 |pages= 149–51 |year= 1994 |pmid= 8192860 |doi=10.1515/bchm3.1994.375.2.149  |display-authors=etal}}
-*{{cite journal  | author=Cavaletto M, Cantisani A, Giuffrida G, ''et al.'' |title=Human alpha S1-casein like protein: purification and N-terminal sequence determination. |journal=Biol. Chem. Hoppe-Seyler |volume=375 |issue= 2 |pages= 149-51 |year= 1994 |pmid= 8192860 |doi=  }}
+*{{cite journal  | vauthors=Murakami K, Lagarde M, Yuki Y |title=Identification of minor proteins of human colostrum and mature milk by two-dimensional electrophoresis. |journal=Electrophoresis |volume=19 |issue= 14 |pages= 2521–7 |year= 1999 |pmid= 9820977 |doi= 10.1002/elps.1150191427 }}
-*{{cite journal  | author=Fujiwara Y, Miwa M, Nogami M, ''et al.'' |title=Genomic organization and chromosomal localization of the human casein gene family. |journal=Hum. Genet. |volume=99 |issue= 3 |pages= 368-73 |year= 1997 |pmid= 9050925 |doi=  }}
+*{{cite journal  | vauthors=Silljé HH, Takahashi K, Tanaka K |title=Mammalian homologues of the plant Tousled gene code for cell-cycle-regulated kinases with maximal activities linked to ongoing DNA replication. |journal=EMBO J. |volume=18 |issue= 20 |pages= 5691–702 |year= 1999 |pmid= 10523312 |doi= 10.1093/emboj/18.20.5691  | pmc=1171636 |display-authors=etal}}
-*{{cite journal  | author=Murakami K, Lagarde M, Yuki Y |title=Identification of minor proteins of human colostrum and mature milk by two-dimensional electrophoresis. |journal=Electrophoresis |volume=19 |issue= 14 |pages= 2521-7 |year= 1999 |pmid= 9820977 |doi= 10.1002/elps.1150191427 }}
+*{{cite journal  | vauthors=Menegay HJ, Myers MP, Moeslein FM, Landreth GE |title=Biochemical characterization and localization of the dual specificity kinase CLK1.  | series=113 |journal=J. Cell Sci. |volume=( Pt 18) |issue=  |pages= 3241–53 |year= 2000 |pmid= 10954422 |doi=  }}
-*{{cite journal  | author=Silljé HH, Takahashi K, Tanaka K, ''et al.'' |title=Mammalian homologues of the plant Tousled gene code for cell-cycle-regulated kinases with maximal activities linked to ongoing DNA replication. |journal=EMBO J. |volume=18 |issue= 20 |pages= 5691-702 |year= 1999 |pmid= 10523312 |doi= 10.1093/emboj/18.20.5691 }}
+*{{cite journal  | vauthors=Gray CW, Ward RV, Karran E |title=Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response. |journal=Eur. J. Biochem. |volume=267 |issue= 18 |pages= 5699–710 |year= 2000 |pmid= 10971580 |doi=10.1046/j.1432-1327.2000.01589.x  |display-authors=etal}}
-*{{cite journal  | author=Menegay HJ, Myers MP, Moeslein FM, Landreth GE |title=Biochemical characterization and localization of the dual specificity kinase CLK1. |journal=J. Cell. Sci. |volume=113 ( Pt 18) |issue=  |pages= 3241-53 |year= 2000 |pmid= 10954422 |doi=  }}
+*{{cite journal  | vauthors=Harrington JJ, Sherf B, Rundlett S |title=Creation of genome-wide protein expression libraries using random activation of gene expression. |journal=Nat. Biotechnol. |volume=19 |issue= 5 |pages= 440–5 |year= 2001 |pmid= 11329013 |doi= 10.1038/88107 |display-authors=etal}}
-*{{cite journal  | author=Gray CW, Ward RV, Karran E, ''et al.'' |title=Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response. |journal=Eur. J. Biochem. |volume=267 |issue= 18 |pages= 5699-710 |year= 2000 |pmid= 10971580 |doi=  }}
+*{{cite journal  | vauthors=Kashiwaba M, Katsura K, Ohnishi M |title=A novel protein phosphatase 2C family member (PP2Czeta) is able to associate with ubiquitin conjugating enzyme 9. |journal=FEBS Lett. |volume=538 |issue= 1-3 |pages= 197–202 |year= 2003 |pmid= 12633878 |doi=10.1016/S0014-5793(03)00153-4  |display-authors=etal}}
-*{{cite journal  | author=Harrington JJ, Sherf B, Rundlett S, ''et al.'' |title=Creation of genome-wide protein expression libraries using random activation of gene expression. |journal=Nat. Biotechnol. |volume=19 |issue= 5 |pages= 440-5 |year= 2001 |pmid= 11329013 |doi= 10.1038/88107 }}
+*{{cite journal  | vauthors=Xu K, Ling MT, Wang X, Wong YC |title=Evidence of a novel biomarker, alphas1-Casein, a milk protein, in benign prostate hyperplasia. |journal=Prostate Cancer Prostatic Dis. |volume=9 |issue= 3 |pages= 293–7 |year= 2007 |pmid= 16683014 |doi= 10.1038/sj.pcan.4500872 }}
-*{{cite journal  | author=Kashiwaba M, Katsura K, Ohnishi M, ''et al.'' |title=A novel protein phosphatase 2C family member (PP2Czeta) is able to associate with ubiquitin conjugating enzyme 9. |journal=FEBS Lett. |volume=538 |issue= 1-3 |pages= 197-202 |year= 2003 |pmid= 12633878 |doi=  }}
-*{{cite journal  | author=Xu K, Ling MT, Wang X, Wong YC |title=Evidence of a novel biomarker, alphas1-Casein, a milk protein, in benign prostate hyperplasia. |journal=Prostate Cancer Prostatic Dis. |volume=9 |issue= 3 |pages= 293-7 |year= 2007 |pmid= 16683014 |doi= 10.1038/sj.pcan.4500872 }}
 }}
 {{refend}}
-{{protein-stub}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
-{{WikiDoc Sources}}
+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
+| update_summary = yes
+| update_citations = yes
+}}
+{{gene-4-stub}}

CSN1S1: Difference between revisions

Revision as of 19:37, 8 November 2017

Contents

Interactions

References

External links

Further reading

Navigation menu