CSRP1: Difference between revisions

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Revision as of 10:07, 30 August 2017

Cysteine and glycine-rich protein 1 is a protein that in humans is encoded by the CSRP1 gene.^[1]^[2]^[3]

CSRP1 is a member of the CSRP family of genes encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in CRP1 is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation Other genes in the family include CSRP2 and CSRP3.^[3]

References

↑ Liebhaber SA, Emery JG, Urbanek M, Wang XK, Cooke NE (Aug 1990). "Characterization of a human cDNA encoding a widely expressed and highly conserved cysteine-rich protein with an unusual zinc-finger motif". Nucleic Acids Res. 18 (13): 3871–9. doi:10.1093/nar/18.13.3871. PMC 331088. PMID 2115670.
↑ Erdel M, Weiskirchen R (Mar 1999). "Assignment1 of CSRP1 encoding the LIM domain protein CRP1, to human chromosome 1q32 by fluorescence in situ hybridization". Cytogenet Cell Genet. 83 (1–2): 10–1. doi:10.1159/000015152. PMID 9925910.
↑ ^3.0 ^3.1 "Entrez Gene: CSRP1 cysteine and glycine-rich protein 1".

External links

Human CRP genome location and CRP gene details page in the UCSC Genome Browser.
Human CSRP1 genome location and CSRP1 gene details page in the UCSC Genome Browser.

Weiskirchen R, Günther K (2003). "The CRP/MLP/TLP family of LIM domain proteins: acting by connecting". BioEssays. 25 (2): 152–62. doi:10.1002/bies.10226. PMID 12539241.
Wang X, Lee G, Liebhaber SA, Cooke NE (1992). "Human cysteine-rich protein. A member of the LIM/double-finger family displaying coordinate serum induction with c-myc". J. Biol. Chem. 267 (13): 9176–84. PMID 1374386.
Wang X, Ray K, Szpirer J, et al. (1992). "Analysis of the human cysteine-rich protein gene (CSRP), assignment to chromosome 1q24-1q32, and identification of an associated MspI polymorphism". Genomics. 14 (2): 391–7. doi:10.1016/S0888-7543(05)80231-9. PMID 1385304.
Feuerstein R, Wang X, Song D, et al. (1994). "The LIM/double zinc-finger motif functions as a protein dimerization domain". Proc. Natl. Acad. Sci. U.S.A. 91 (22): 10655–9. doi:10.1073/pnas.91.22.10655. PMC 45080. PMID 7938009.
Dubé JY, Chapdelaine P, Trahan PL, et al. (1998). "Abundant cysteine-rich protein-1 is localized in the stromal compartment of the human prostate". Arch. Androl. 40 (2): 109–15. doi:10.3109/01485019808987933. PMID 9507743.
Harper BD, Beckerle MC, Pomiès P (2001). "Fine mapping of the alpha-actinin binding site within cysteine-rich protein". Biochem. J. 350 Pt 1 (Pt 1): 269–74. doi:10.1042/0264-6021:3500269. PMC 1221251. PMID 10926853.
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Hirasawa Y, Arai M, Imazeki F, et al. (2007). "Methylation status of genes upregulated by demethylating agent 5-aza-2'-deoxycytidine in hepatocellular carcinoma". Oncology. 71 (1–2): 77–85. doi:10.1159/000100475. PMID 17341888.
Wang Q, Williamson M, Bott S, et al. (2007). "Hypomethylation of WNT5A, CRIP1 and S100P in prostate cancer". Oncogene. 26 (45): 6560–5. doi:10.1038/sj.onc.1210472. PMID 17486081.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

[pmid2115670-1] Liebhaber SA, Emery JG, Urbanek M, Wang XK, Cooke NE (Aug 1990). "Characterization of a human cDNA encoding a widely expressed and highly conserved cysteine-rich protein with an unusual zinc-finger motif". Nucleic Acids Res. 18 (13): 3871–9. doi:10.1093/nar/18.13.3871. PMC 331088. PMID 2115670.

[pmid9925910-2] Erdel M, Weiskirchen R (Mar 1999). "Assignment1 of CSRP1 encoding the LIM domain protein CRP1, to human chromosome 1q32 by fluorescence in situ hybridization". Cytogenet Cell Genet. 83 (1–2): 10–1. doi:10.1159/000015152. PMID 9925910.

[entrez-3] 3.0 ^3.1 "Entrez Gene: CSRP1 cysteine and glycine-rich protein 1".

[1]

[2]

[3]

@@ Line 1: / Line 1: @@
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+{{Infobox_gene}}
-{{GNF_Protein_box
+'''Cysteine and glycine-rich protein 1''' is a [[protein]] that in humans is encoded by the ''CSRP1'' [[gene]].<ref name="pmid2115670">{{cite journal | vauthors = Liebhaber SA, Emery JG, Urbanek M, Wang XK, Cooke NE | title = Characterization of a human cDNA encoding a widely expressed and highly conserved cysteine-rich protein with an unusual zinc-finger motif | journal = Nucleic Acids Res | volume = 18 | issue = 13 | pages = 3871–9 |date=Aug 1990 | pmid = 2115670 | pmc = 331088 | doi =10.1093/nar/18.13.3871  }}</ref><ref name="pmid9925910">{{cite journal | vauthors = Erdel M, Weiskirchen R | title = Assignment1 of CSRP1 encoding the LIM domain protein CRP1, to human chromosome 1q32 by fluorescence in situ hybridization | journal = Cytogenet Cell Genet | volume = 83 | issue = 1–2 | pages = 10–1 |date=Mar 1999 | pmid = 9925910 | pmc =  | doi =10.1159/000015152  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CSRP1 cysteine and glycine-rich protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1465| accessdate = }}</ref>
- | image = PBB_Protein_CSRP1_image.jpg
- | image_source = [[Protein_Data_Bank|PDB]] rendering based on 1ctl.
- | PDB = {{PDB2|1ctl}}
- | Name = Cysteine and glycine-rich protein 1
- | HGNCid = 2469
- | Symbol = CSRP1
- | AltSymbols =; CRP1; CRP; CSRP; CYRP; D1S181E; DKFZp686M148
- | OMIM = 123876
- | ECnumber =
- | Homologene = 37874
- | MGIid = 88549
- | GeneAtlas_image1 = PBB_GE_CSRP1_200621_at_tn.png
-  | Function = {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
- | Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
- | Process =
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 1465
-    | Hs_Ensembl = ENSG00000159176
-    | Hs_RefseqProtein = NP_004069
-    | Hs_RefseqmRNA = NM_004078
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 1
-    | Hs_GenLoc_start = 199719281
-    | Hs_GenLoc_end = 199745207
-    | Hs_Uniprot = P21291
-    | Mm_EntrezGene = 13007
-    | Mm_Ensembl = ENSMUSG00000026421
-    | Mm_RefseqmRNA = NM_007791
-    | Mm_RefseqProtein = NP_031817
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 1
-    | Mm_GenLoc_start = 137536472
-    | Mm_GenLoc_end = 137568640
-    | Mm_Uniprot = Q4FJX4
-  }}
-}}
-'''Cysteine and glycine-rich protein 1''', also known as '''CSRP1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CSRP1 cysteine and glycine-rich protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1465| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
 {{PBB_Summary
 | section_title =
-| summary_text = CSRP1 is a member of the CSRP family of genes encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation.  The LIM/double zinc-finger motif found in CRP1 is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation  Other genes in the family include CSRP2 and CSRP3.<ref name="entrez">{{cite web | title = Entrez Gene: CSRP1 cysteine and glycine-rich protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1465| accessdate = }}</ref>
+| summary_text = CSRP1 is a member of the CSRP family of genes encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation.  The LIM/double zinc-finger motif found in CRP1 is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation  Other genes in the family include CSRP2 and CSRP3.<ref name="entrez" />
 }}
 ==References==
-{{reflist|2}}
+{{reflist}}
+==External links==
+* {{UCSC gene info|CRP}}
+* {{UCSC gene info|CSRP1}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Weiskirchen R, Günther K |title=The CRP/MLP/TLP family of LIM domain proteins: acting by connecting. |journal=Bioessays |volume=25 |issue= 2 |pages= 152-62 |year= 2003 |pmid= 12539241 |doi= 10.1002/bies.10226 }}
+*{{cite journal  | vauthors=Weiskirchen R, Günther K |title=The CRP/MLP/TLP family of LIM domain proteins: acting by connecting |journal=BioEssays |volume=25 |issue= 2 |pages= 152–62 |year= 2003 |pmid= 12539241 |doi= 10.1002/bies.10226 }}
-*{{cite journal  | author=Wang X, Lee G, Liebhaber SA, Cooke NE |title=Human cysteine-rich protein. A member of the LIM/double-finger family displaying coordinate serum induction with c-myc. |journal=J. Biol. Chem. |volume=267 |issue= 13 |pages= 9176-84 |year= 1992 |pmid= 1374386 |doi=  }}
+*{{cite journal  | vauthors=Wang X, Lee G, Liebhaber SA, Cooke NE |title=Human cysteine-rich protein. A member of the LIM/double-finger family displaying coordinate serum induction with c-myc |journal=J. Biol. Chem. |volume=267 |issue= 13 |pages= 9176–84 |year= 1992 |pmid= 1374386 |doi=  }}
-*{{cite journal  | author=Wang X, Ray K, Szpirer J, ''et al.'' |title=Analysis of the human cysteine-rich protein gene (CSRP), assignment to chromosome 1q24-1q32, and identification of an associated MspI polymorphism. |journal=Genomics |volume=14 |issue= 2 |pages= 391-7 |year= 1992 |pmid= 1385304 |doi=  }}
+*{{cite journal  | vauthors=Wang X, Ray K, Szpirer J |title=Analysis of the human cysteine-rich protein gene (CSRP), assignment to chromosome 1q24-1q32, and identification of an associated MspI polymorphism |journal=Genomics |volume=14 |issue= 2 |pages= 391–7 |year= 1992 |pmid= 1385304 |doi=10.1016/S0888-7543(05)80231-9  |display-authors=etal}}
-*{{cite journal  | author=Liebhaber SA, Emery JG, Urbanek M, ''et al.'' |title=Characterization of a human cDNA encoding a widely expressed and highly conserved cysteine-rich protein with an unusual zinc-finger motif. |journal=Nucleic Acids Res. |volume=18 |issue= 13 |pages= 3871-9 |year= 1990 |pmid= 2115670 |doi=  }}
+*{{cite journal  | vauthors=Feuerstein R, Wang X, Song D |title=The LIM/double zinc-finger motif functions as a protein dimerization domain |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 22 |pages= 10655–9 |year= 1994 |pmid= 7938009 |doi=10.1073/pnas.91.22.10655  | pmc=45080  |display-authors=etal}}
-*{{cite journal  | author=Feuerstein R, Wang X, Song D, ''et al.'' |title=The LIM/double zinc-finger motif functions as a protein dimerization domain. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 22 |pages= 10655-9 |year= 1994 |pmid= 7938009 |doi=  }}
+*{{cite journal  | vauthors=Dubé JY, Chapdelaine P, Trahan PL |title=Abundant cysteine-rich protein-1 is localized in the stromal compartment of the human prostate |journal=Arch. Androl. |volume=40 |issue= 2 |pages= 109–15 |year= 1998 |pmid= 9507743 |doi=10.3109/01485019808987933  |display-authors=etal}}
-*{{cite journal  | author=Dubé JY, Chapdelaine P, Trahan PL, ''et al.'' |title=Abundant cysteine-rich protein-1 is localized in the stromal compartment of the human prostate. |journal=Arch. Androl. |volume=40 |issue= 2 |pages= 109-15 |year= 1998 |pmid= 9507743 |doi=  }}
+*{{cite journal  | vauthors=Harper BD, Beckerle MC, Pomiès P |title=Fine mapping of the alpha-actinin binding site within cysteine-rich protein |journal=Biochem. J. |volume=350 Pt 1 |issue=  Pt 1|pages= 269–74 |year= 2001 |pmid= 10926853 |doi=  10.1042/0264-6021:3500269| pmc=1221251  }}
-*{{cite journal  | author=Erdel M, Weiskirchen R |title=Assignment1 of CSRP1 encoding the LIM domain protein CRP1, to human chromosome 1q32 by fluorescence in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=83 |issue= 1-2 |pages= 10-1 |year= 1999 |pmid= 9925910 |doi=  }}
+*{{cite journal  | vauthors=Andersen JS, Lyon CE, Fox AH |title=Directed proteomic analysis of the human nucleolus |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=10.1016/S0960-9822(01)00650-9  |display-authors=etal}}
-*{{cite journal  | author=Harper BD, Beckerle MC, Pomiès P |title=Fine mapping of the alpha-actinin binding site within cysteine-rich protein. |journal=Biochem. J. |volume=350 Pt 1 |issue=  |pages= 269-74 |year= 2001 |pmid= 10926853 |doi=  }}
+*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |display-authors=etal}}
-*{{cite journal  | author=Andersen JS, Lyon CE, Fox AH, ''et al.'' |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1-11 |year= 2002 |pmid= 11790298 |doi=  }}
+*{{cite journal  | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 |display-authors=etal}}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
+*{{cite journal  | vauthors=Beausoleil SA, Villén J, Gerber SA |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 |display-authors=etal}}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal  | vauthors=Olsen JV, Blagoev B, Gnad F |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 |display-authors=etal}}
-*{{cite journal  | author=Beausoleil SA, Villén J, Gerber SA, ''et al.'' |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285-92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 }}
+*{{cite journal  | vauthors=Hirasawa Y, Arai M, Imazeki F |title=Methylation status of genes upregulated by demethylating agent 5-aza-2'-deoxycytidine in hepatocellular carcinoma |journal=Oncology |volume=71 |issue= 1–2 |pages= 77–85 |year= 2007 |pmid= 17341888 |doi= 10.1159/000100475 |display-authors=etal}}
-*{{cite journal  | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
+*{{cite journal  | vauthors=Wang Q, Williamson M, Bott S |title=Hypomethylation of WNT5A, CRIP1 and S100P in prostate cancer |journal=Oncogene |volume=26 |issue= 45 |pages= 6560–5 |year= 2007 |pmid= 17486081 |doi= 10.1038/sj.onc.1210472 |display-authors=etal}}
-*{{cite journal  | author=Hirasawa Y, Arai M, Imazeki F, ''et al.'' |title=Methylation status of genes upregulated by demethylating agent 5-aza-2'-deoxycytidine in hepatocellular carcinoma. |journal=Oncology |volume=71 |issue= 1-2 |pages= 77-85 |year= 2007 |pmid= 17341888 |doi= 10.1159/000100475 }}
-*{{cite journal  | author=Wang Q, Williamson M, Bott S, ''et al.'' |title=Hypomethylation of WNT5A, CRIP1 and S100P in prostate cancer. |journal=Oncogene |volume=26 |issue= 45 |pages= 6560-5 |year= 2007 |pmid= 17486081 |doi= 10.1038/sj.onc.1210472 }}
 }}
 {{refend}}
+{{PDB Gallery|geneid=1465}}
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+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
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+| update_citations = yes
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-{{WikiDoc Sources}}

CSRP1: Difference between revisions

Revision as of 10:07, 30 August 2017

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