Tropical sprue medical therapy: Difference between revisions
Jump to navigation
Jump to search
Created page with "{{Tropical sprue}} {{CMG}} ==Overview== ==Medical Therapy== ===Pharmacotherapy=== Treatment begins with plenty of fluids and electrolytes. Replacement of folate, iron, vi..." |
No edit summary |
||
| Line 4: | Line 4: | ||
==Overview== | ==Overview== | ||
Treatment begins with plenty of fluids and electrolytes. Replacement of folate, iron, vitamin B12, and other nutrients may also be needed. Antibiotic therapy with tetracycline is given at the beginning of treatment. | |||
Oral tetracycline is usually not prescribed for children until after all permanent teeth have appeared. It can permanently discolor teeth that are still forming. | |||
==Medical Therapy== | ==Medical Therapy== | ||
=== | * Tropical sprue<ref>{{Cite journal| issn = 0003-4819| volume = 63| issue = 4| pages = 619–634| last1 = Guerra| first1 = R.| last2 = Wheby| first2 = M. S.| last3 = Bayless| first3 = T. M.| title = Long-term antibiotic therapy in tropical sprue| journal = Annals of Internal Medicine| date = 1965-10| pmid = 5838328}}</ref><ref>{{cite book | last = Ferri | first = Fred | title = Ferri's Clinical Advisor 2016 5 Books in 1 | publisher = Elsevier Science Health Science | location = City | year = 2015 | isbn = 978-0323280471 }}</ref> | ||
:* Preferred regimen (1): [[Folic acid]] 5 mg PO bid for 2 weeks, followed by 1 mg PO tid {{and}} [[Tetracycline]] 250 mg PO qid for 4–6 weeks, up to 6 months in residents of the tropics who have had long-term disease | |||
:* Preferred regimen (2): [[Folic acid]] 5 mg PO bid for 2 weeks, followed by 1 mg PO tid {{and}} [[Doxycycline]] 100 mg PO qd for 4–6 weeks, up to 6 months in residents of the tropics who have had long-term disease | |||
:* Alternative regimen: [[Folic acid]] 5 mg PO bid for 2 weeks, followed by 1 mg PO tid {{and}} [[Ampicillin]] 500 mg bid for ≥ 4 weeks | |||
:: Note: Vitamin B12 deficiency may be corrected with [[Vitamin B12]] 1000 mcg IM weekly for 4 weeks, followed by monthly for 3 to 6 months. | |||
===Chronic Pharmacotherapies=== | |||
Once diagnosed, tropical sprue can be treated by a course of the antibiotic [[tetracycline]] and vitamins B12 and folic acid for at least 6 months. | Once diagnosed, tropical sprue can be treated by a course of the antibiotic [[tetracycline]] and vitamins B12 and folic acid for at least 6 months. | ||
Revision as of 21:20, 11 August 2015
|
Tropical sprue Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Tropical sprue medical therapy On the Web |
|
American Roentgen Ray Society Images of Tropical sprue medical therapy |
|
Risk calculators and risk factors for Tropical sprue medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Treatment begins with plenty of fluids and electrolytes. Replacement of folate, iron, vitamin B12, and other nutrients may also be needed. Antibiotic therapy with tetracycline is given at the beginning of treatment.
Oral tetracycline is usually not prescribed for children until after all permanent teeth have appeared. It can permanently discolor teeth that are still forming.
Medical Therapy
- Preferred regimen (1): Folic acid 5 mg PO bid for 2 weeks, followed by 1 mg PO tid AND Tetracycline 250 mg PO qid for 4–6 weeks, up to 6 months in residents of the tropics who have had long-term disease
- Preferred regimen (2): Folic acid 5 mg PO bid for 2 weeks, followed by 1 mg PO tid AND Doxycycline 100 mg PO qd for 4–6 weeks, up to 6 months in residents of the tropics who have had long-term disease
- Alternative regimen: Folic acid 5 mg PO bid for 2 weeks, followed by 1 mg PO tid AND Ampicillin 500 mg bid for ≥ 4 weeks
- Note: Vitamin B12 deficiency may be corrected with Vitamin B12 1000 mcg IM weekly for 4 weeks, followed by monthly for 3 to 6 months.
Chronic Pharmacotherapies
Once diagnosed, tropical sprue can be treated by a course of the antibiotic tetracycline and vitamins B12 and folic acid for at least 6 months.
References
- ↑ Guerra, R.; Wheby, M. S.; Bayless, T. M. (1965-10). "Long-term antibiotic therapy in tropical sprue". Annals of Internal Medicine. 63 (4): 619–634. ISSN 0003-4819. PMID 5838328. Check date values in:
|date=(help) - ↑ Ferri, Fred (2015). Ferri's Clinical Advisor 2016 5 Books in 1. City: Elsevier Science Health Science. ISBN 978-0323280471.