GPX7: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
m (Robot: Automated text replacement (-{{WikiDoc Cardiology Network Infobox}} +, -<references /> +{{reflist|2}}, -{{reflist}} +{{reflist|2}}))
 
m (Bot: HTTP→HTTPS)
 
Line 1: Line 1:
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Glutathione peroxidase 7''' is an [[enzyme]] that in humans is encoded by the ''GPX7'' [[gene]].<ref name="pmid15294905">{{cite journal |vauthors=Utomo A, Jiang X, Furuta S, Yun J, Levin DS, Wang YC, Desai KV, Green JE, Chen PL, Lee WH | title = Identification of a novel putative non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase (NPGPx) essential for alleviating oxidative stress generated from polyunsaturated fatty acids in breast cancer cells | journal = J Biol Chem | volume = 279 | issue = 42 | pages = 43522–9 |date=Oct 2004 | pmid = 15294905 | pmc =  | doi = 10.1074/jbc.M407141200 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: GPX7 glutathione peroxidase 7| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2882| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
 
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image = PBB_Protein_GPX7_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 2p31.
| PDB = {{PDB2|2p31}}
| Name = Glutathione peroxidase 7
| HGNCid = 4559
| Symbol = GPX7
| AltSymbols =; CL683; FLJ14777; GPX6; NPGPx
| OMIM = 
| ECnumber = 
| Homologene = 84388
| MGIid = 1914555
| GeneAtlas_image1 = PBB_GE_GPX7_213170_at_tn.png
| Function = {{GNF_GO|id=GO:0004602 |text = glutathione peroxidase activity}} {{GNF_GO|id=GO:0016491 |text = oxidoreductase activity}}
| Component =
| Process = {{GNF_GO|id=GO:0006979 |text = response to oxidative stress}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 2882
    | Hs_Ensembl = ENSG00000116157
    | Hs_RefseqProtein = NP_056511
    | Hs_RefseqmRNA = NM_015696
    | Hs_GenLoc_db =
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 52840632
    | Hs_GenLoc_end = 52847311
    | Hs_Uniprot = Q96SL4
    | Mm_EntrezGene = 67305
    | Mm_Ensembl = ENSMUSG00000028597
    | Mm_RefseqmRNA = NM_024198
    | Mm_RefseqProtein = NP_077160
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 4
    | Mm_GenLoc_start = 107898322
    | Mm_GenLoc_end = 107904646
    | Mm_Uniprot = Q3TNK3
  }}
}}
'''Glutathione peroxidase 7''', also known as '''GPX7''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GPX7 glutathione peroxidase 7| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2882| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
Line 55: Line 9:


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Opalenik SR, Ding Q, Mallery SR, Thompson JA |title=Glutathione depletion associated with the HIV-1 TAT protein mediates the extracellular appearance of acidic fibroblast growth factor. |journal=Arch. Biochem. Biophys. |volume=351 |issue= 1 |pages= 17-26 |year= 1998 |pmid= 9501919 |doi= 10.1006/abbi.1997.0566 }}
*{{cite journal  |vauthors=Opalenik SR, Ding Q, Mallery SR, Thompson JA |title=Glutathione depletion associated with the HIV-1 TAT protein mediates the extracellular appearance of acidic fibroblast growth factor. |journal=Arch. Biochem. Biophys. |volume=351 |issue= 1 |pages= 17–26 |year= 1998 |pmid= 9501919 |doi= 10.1006/abbi.1997.0566 }}
*{{cite journal | author=Choi J, Liu RM, Kundu RK, ''et al.'' |title=Molecular mechanism of decreased glutathione content in human immunodeficiency virus type 1 Tat-transgenic mice. |journal=J. Biol. Chem. |volume=275 |issue= 5 |pages= 3693-8 |year= 2000 |pmid= 10652368 |doi=  }}
*{{cite journal   |vauthors=Choi J, Liu RM, Kundu RK, etal |title=Molecular mechanism of decreased glutathione content in human immunodeficiency virus type 1 Tat-transgenic mice. |journal=J. Biol. Chem. |volume=275 |issue= 5 |pages= 3693–8 |year= 2000 |pmid= 10652368 |doi=10.1074/jbc.275.5.3693 }}
*{{cite journal | author=Richard MJ, Guiraud P, Didier C, ''et al.'' |title=Human immunodeficiency virus type 1 Tat protein impairs selenoglutathione peroxidase expression and activity by a mechanism independent of cellular selenium uptake: consequences on cellular resistance to UV-A radiation. |journal=Arch. Biochem. Biophys. |volume=386 |issue= 2 |pages= 213-20 |year= 2001 |pmid= 11368344 |doi= 10.1006/abbi.2000.2197 }}
*{{cite journal   |vauthors=Richard MJ, Guiraud P, Didier C, etal |title=Human immunodeficiency virus type 1 Tat protein impairs selenoglutathione peroxidase expression and activity by a mechanism independent of cellular selenium uptake: consequences on cellular resistance to UV-A radiation. |journal=Arch. Biochem. Biophys. |volume=386 |issue= 2 |pages= 213–20 |year= 2001 |pmid= 11368344 |doi= 10.1006/abbi.2000.2197 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Clark HF, Gurney AL, Abaya E, ''et al.'' |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265-70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 }}
*{{cite journal   |vauthors=Clark HF, Gurney AL, Abaya E, etal |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 | pmc=403697 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Utomo A, Jiang X, Furuta S, ''et al.'' |title=Identification of a novel putative non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase (NPGPx) essential for alleviating oxidative stress generated from polyunsaturated fatty acids in breast cancer cells. |journal=J. Biol. Chem. |volume=279 |issue= 42 |pages= 43522-9 |year= 2004 |pmid= 15294905 |doi= 10.1074/jbc.M407141200 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  |vauthors=Price TO, Ercal N, Nakaoke R, Banks WA |title=HIV-1 viral proteins gp120 and Tat induce oxidative stress in brain endothelial cells. |journal=Brain Res. |volume=1045 |issue= 1–2 |pages= 57–63 |year= 2005 |pmid= 15910762 |doi= 10.1016/j.brainres.2005.03.031 }}
*{{cite journal  | author=Price TO, Ercal N, Nakaoke R, Banks WA |title=HIV-1 viral proteins gp120 and Tat induce oxidative stress in brain endothelial cells. |journal=Brain Res. |volume=1045 |issue= 1-2 |pages= 57-63 |year= 2005 |pmid= 15910762 |doi= 10.1016/j.brainres.2005.03.031 }}
*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal   |vauthors=Gregory SG, Barlow KF, McLay KE, etal |title=The DNA sequence and biological annotation of human chromosome 1 |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
*{{cite journal | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
*{{cite journal   |vauthors=Lim J, Hao T, Shaw C, etal |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032 }}
*{{cite journal | author=Lim J, Hao T, Shaw C, ''et al.'' |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801-14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032 }}
}}
}}
{{refend}}
{{refend}}


{{protein-stub}}
{{PDB Gallery|geneid=2882}}
{{WikiDoc Sources}}
{{Peroxidases}}
{{Enzymes}}
{{Portal bar|Molecular and Cellular Biology|border=no}}
 
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
 
[[Category:EC 1.11.1]]
 
 
{{gene-1-stub}}

Latest revision as of 09:03, 31 August 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Glutathione peroxidase 7 is an enzyme that in humans is encoded by the GPX7 gene.[1][2]


References

  1. ↑ Utomo A, Jiang X, Furuta S, Yun J, Levin DS, Wang YC, Desai KV, Green JE, Chen PL, Lee WH (Oct 2004). "Identification of a novel putative non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase (NPGPx) essential for alleviating oxidative stress generated from polyunsaturated fatty acids in breast cancer cells". J Biol Chem. 279 (42): 43522–9. doi:10.1074/jbc.M407141200. PMID 15294905.
  2. ↑ "Entrez Gene: GPX7 glutathione peroxidase 7".

Further reading


Retrieved from "https://www.wikidoc.org/index.php?title=GPX7&oldid=1411218"