IFNA5: Difference between revisions

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{{Infobox_gene}}
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'''Interferon alpha-5''' is a [[protein]] that in humans is encoded by the ''IFNA5'' [[gene]].<ref name="pmid1385305">{{cite journal |vauthors=Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO | title = Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia | journal = Genomics | volume = 14 | issue = 2 | pages = 437–43 |date=Dec 1992 | pmid = 1385305 | pmc =  | doi =10.1016/S0888-7543(05)80238-1 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: IFNA5 interferon, alpha 5| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3442| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =  
| Name = Interferon, alpha 5
| HGNCid = 5426
| Symbol = IFNA5
| AltSymbols =; INFA5
| OMIM = 147565
| ECnumber =
| Homologene = 88659
| MGIid = 107664
  | GeneAtlas_image1 = PBB_GE_IFNA5_214569_at_tn.png
| Function = {{GNF_GO|id=GO:0005126 |text = hematopoietin/interferon-class (D200-domain) cytokine receptor binding}}
| Component = {{GNF_GO|id=GO:0005576 |text = extracellular region}} {{GNF_GO|id=GO:0005615 |text = extracellular space}}
  | Process = {{GNF_GO|id=GO:0006952 |text = defense response}} {{GNF_GO|id=GO:0009615 |text = response to virus}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 3442
    | Hs_Ensembl = ENSG00000147873
    | Hs_RefseqProtein = NP_002160
    | Hs_RefseqmRNA = NM_002169
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 9
    | Hs_GenLoc_start = 21294325
    | Hs_GenLoc_end = 21295311
    | Hs_Uniprot = P01569
    | Mm_EntrezGene = 15967
    | Mm_Ensembl = ENSMUSG00000070904
    | Mm_RefseqmRNA = NM_010504
    | Mm_RefseqProtein = NP_034634
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 4
    | Mm_GenLoc_start = 88313092
    | Mm_GenLoc_end = 88313652
    | Mm_Uniprot = Q540C2
  }}
}}
'''Interferon, alpha 5''', also known as '''IFNA5''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: IFNA5 interferon, alpha 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3442| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Olopade OI, Bohlander SK, Pomykala H, ''et al.'' |title=Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia. |journal=Genomics |volume=14 |issue= 2 |pages= 437-43 |year= 1992 |pmid= 1385305 |doi=  }}
*{{cite journal   |vauthors=Henco K, Brosius J, Fujisawa A, etal |title=Structural relationship of human interferon alpha genes and pseudogenes. |journal=J. Mol. Biol. |volume=185 |issue= 2 |pages= 227–60 |year= 1985 |pmid= 4057246 |doi=10.1016/0022-2836(85)90401-2 }}
*{{cite journal  | author=Henco K, Brosius J, Fujisawa A, ''et al.'' |title=Structural relationship of human interferon alpha genes and pseudogenes. |journal=J. Mol. Biol. |volume=185 |issue= 2 |pages= 227-60 |year= 1985 |pmid= 4057246 |doi=  }}
*{{cite journal   |vauthors=Goeddel DV, Leung DW, Dull TJ, etal |title=The structure of eight distinct cloned human leukocyte interferon cDNAs. |journal=Nature |volume=290 |issue= 5801 |pages= 20–6 |year= 1981 |pmid= 6163083 |doi=10.1038/290020a0 }}
*{{cite journal | author=Goeddel DV, Leung DW, Dull TJ, ''et al.'' |title=The structure of eight distinct cloned human leukocyte interferon cDNAs. |journal=Nature |volume=290 |issue= 5801 |pages= 20-6 |year= 1981 |pmid= 6163083 |doi=  }}
*{{cite journal   |vauthors=Tiefenbrun N, Melamed D, Levy N, etal |title=Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest. |journal=Mol. Cell. Biol. |volume=16 |issue= 7 |pages= 3934–44 |year= 1996 |pmid= 8668211 |doi= | pmc=231390 }}
*{{cite journal | author=Tiefenbrun N, Melamed D, Levy N, ''et al.'' |title=Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest. |journal=Mol. Cell. Biol. |volume=16 |issue= 7 |pages= 3934-44 |year= 1996 |pmid= 8668211 |doi=  }}
*{{cite journal   |vauthors=Chuntharapai A, Gibbs V, Lu J, etal |title=Determination of residues involved in ligand binding and signal transmission in the human IFN-alpha receptor 2. |journal=J. Immunol. |volume=163 |issue= 2 |pages= 766–73 |year= 1999 |pmid= 10395669 |doi=  }}
*{{cite journal | author=Chuntharapai A, Gibbs V, Lu J, ''et al.'' |title=Determination of residues involved in ligand binding and signal transmission in the human IFN-alpha receptor 2. |journal=J. Immunol. |volume=163 |issue= 2 |pages= 766-73 |year= 1999 |pmid= 10395669 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Humphray SJ, Oliver K, Hunt AR, etal |title=DNA sequence and analysis of human chromosome 9. |journal=Nature |volume=429 |issue= 6990 |pages= 369–74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465 | pmc=2734081 }}
*{{cite journal | author=Humphray SJ, Oliver K, Hunt AR, ''et al.'' |title=DNA sequence and analysis of human chromosome 9. |journal=Nature |volume=429 |issue= 6990 |pages= 369-74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465 }}
*{{cite journal  |vauthors=Zhang Z, Henzel WJ |title=Signal peptide prediction based on analysis of experimentally verified cleavage sites. |journal=Protein Sci. |volume=13 |issue= 10 |pages= 2819–24 |year= 2005 |pmid= 15340161 |doi= 10.1110/ps.04682504 | pmc=2286551 }}
*{{cite journal  | author=Zhang Z, Henzel WJ |title=Signal peptide prediction based on analysis of experimentally verified cleavage sites. |journal=Protein Sci. |volume=13 |issue= 10 |pages= 2819-24 |year= 2005 |pmid= 15340161 |doi= 10.1110/ps.04682504 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
}}
{{refend}}
{{refend}}
{{Cytokine receptor modulators}}
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{{gene-9-stub}}
{{gene-9-stub}}

Revision as of 23:39, 31 August 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Interferon alpha-5 is a protein that in humans is encoded by the IFNA5 gene.[1][2]


References

  1. ↑ Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO (Dec 1992). "Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia". Genomics. 14 (2): 437–43. doi:10.1016/S0888-7543(05)80238-1. PMID 1385305.
  2. ↑ "Entrez Gene: IFNA5 interferon, alpha 5".

Further reading



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