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'''Lanolin''', also called '''Adeps Lanae''', '''wool wax''', '''wool fat''', or '''wool grease''', a greasy yellow substance from wool-bearing animals, acts as a skin ointment, water-proofing wax, and raw material (such as in [[shoe polish]]).  Lanolin is "wool [[fat]]" or grease, chemically akin to [[wax]], which is secreted by the [[sebaceous gland]]s of [[wool]]-bearing animals, such as [[sheep]]. These glands are associated with [[hair follicle]]s.  Lanolin's ability to act as a waterproofing wax aids sheep in shedding [[water]] from their coats.  Certain breeds of sheep produce large amounts of lanolin, and the extraction can be performed by squeezing the wool between rollers.  Most or all the lanolin is removed from wool when it is processed into [[textiles]], eg [[yarn]] or [[felt]].  The Fanning Corporation is the only lanolin producer with a refinery located in the United States.
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Lanolin is chiefly a mixture of [[cholesterol]] and the [[ester]]s of several [[fatty acid]]s. Crude (non-medical) grades of lanolin also contain [[wool alcohol]]s, which are an [[allergen]] for some people. Recent studies also indicate that [[antibiotic]]s are present in the lanolin.  The extract is insoluble in water, but forms an [[emulsion]]. At one point, the name Lanolin was trademarked as the generic term for a preparation of sheep fat and water.
* Content
<ref name="tradecourt">{{cite court 
|litigants=Jaffe v. Evans & Sons, Ltd.
|vol=
|reporter=U.S.
|opinion=
|pinpoint=
|court=Supreme Court, Appellate Division, First Department, New York
|date=March 21, 1902
|url=}}</ref>


Lanolin is used commercially in a great many products ranging from [[rust]]-preventative coatings to [[cosmetics]] to [[lubricant]]s. Some sailors use lanolin to create a slippery surface on their propellers and stern gear to which [[barnacles]] cannot adhere. The water-repellent properties make it valuable as a lubricant grease where corrosion would otherwise be a problem, particularly on stainless steel, which becomes more vulnerable to corrosion when starved of oxygen.
<!--Adult Indications and Dosage-->


'''Medical grade lanolin''' is used as a cream to soothe [[skin]].  It is  pure, [[hypoallergenic]] and [[bacteriostatic]].  In this form it is used by some [[breastfeeding]] mothers on sore and cracked nipples. This grade of lanolin can also be used to treat [[chapped lips]], [[diaper rash]], dry skin, itchy skin, rough feet, minor cuts, minor [[burn (injury)|burns]] and skin abrasions.  As an [[ointment]] base, it is readily absorbed through [[skin]], facilitating absorption of the medicinal chemicals it carries.
<!--FDA-Labeled Indications and Dosage (Adult)-->
|fdaLIADAdult======Condition1=====


The name given to the product '[[Olay|Oil of Olay]]' is derived from the word "lanolin," a key ingredient, which was chosen by the inventor, Graham Wulff.<ref name="olay-wulff">{{cite web | url = http://www.uk.pg.com/products/products/olay.html  | title = History of Olay | publisher = Procter & Gamble}}</ref>
* Dosing Information


Using cosmetic products which contain too much lanolin can result in an allergic reaction in some people.
:* Dosage


Lanolin is often used as a raw material for producing [[Cholecalciferol|vitamin D3]].
=====Condition2=====


==More Information on Lanolin==
* Dosing Information


Lanolin is a unique natural substance derived from the greasy coating on raw wool.  It is an all-natural, highly effective substance which acts as a moisture barrier and lubricant.  Its unique properties have been recognised for centuries, and have not, as yet, been possible for scientists to duplicate.
:* Dosage
In Australia, the use of lanolin became less common from the late 1940s onwards, as the use of harsh toxic chemicals became the industry norm.
In the last few decades however, there has been a shift in people’s attitudes and the realisation that society cannot continue to degrade the environment through the use of petrochemical based products.  Consequently, there has been a move towards using more environmentally friendly alternatives.
Quick facts on lanolin:
*Lanolin is secreted from a sheep’s sebaceous glands and acts as a waterproofer to protect the sheep’s wool from the elements
*It is made up of a mixture of wax, fatty acids and alcohols
*Crude lanolin constitutes approximately 5-25% of the weight of freshly shorn wool
*The wool from one Merino sheep will produce about 250-300ml of recoverable wool grease (lanolin)
*Lanolin is extracted from wool via a scouring process. This process involves washing the wool in hot water with a special wool scouring detergent to remove dirt, wool grease (crude lanolin), suint (sweat salts), and anything else stuck to the wool. The wool grease is continuously removed during this washing process by centrifugal separators, which concentrate the wool grease into a wax-like substance melting at approximately 38ºC.
*To date, scientists have been unable to duplicate either the performance or composition of lanolin.


==References==
=====Condition3=====
{{reflist|2}}
{{E number infobox 910-919}}


[[Category:Animal glandular products]]
* Dosing Information
[[Category:Waxes]]
[[Category:Lubricants]]


[[da:Lanolin]]
:* Dosage
[[de:Wollwachs]]
[[es:Lanolina]]
[[eo:Lanolino]]
[[it:Lanolina]]
[[pl:Lanolina]]
[[pt:Lanolina]]
[[fi:Lanoliini]]
[[sv:Lanolin]]
[[ru:Ланолин]]


==Links==
=====Condition4=====


[http://www.lanotec.com.au] '''Lanotec''' - Lanolin based alternatives to petro-chemical products
* Dosing Information
{{WikiDoc Help Menu}}
 
{{WikiDoc Sources}}
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[[Category:Drug]]

Revision as of 16:04, 22 April 2015

Lanolin
Black Box Warning
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];

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Black Box Warning

ConditionName:
See full prescribing information for complete Boxed Warning.
ConditionName:
  • Content

Overview

Lanolin is a {{{drugClass}}} that is FDA approved for the treatment of {{{indication}}}. There is a Black Box Warning for this drug as shown here. Common adverse reactions include .

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

Condition1
  • Dosing Information
  • Dosage
Condition2
  • Dosing Information
  • Dosage
Condition3
  • Dosing Information
  • Dosage
Condition4
  • Dosing Information
  • Dosage

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

Condition1
  • Developed by:
  • Class of Recommendation:
  • Strength of Evidence:
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding Off-Label Guideline-Supported Use of Lanolin in adult patients.

Non–Guideline-Supported Use

Condition1
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding Off-Label Non–Guideline-Supported Use of Lanolin in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

Condition1
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding FDA-Labeled Use of Lanolin in pediatric patients.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

Condition1
  • Developed by:
  • Class of Recommendation:
  • Strength of Evidence:
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding Off-Label Guideline-Supported Use of Lanolin in pediatric patients.

Non–Guideline-Supported Use

Condition1
  • Dosing Information
  • Dosage
Condition2

There is limited information regarding Off-Label Non–Guideline-Supported Use of Lanolin in pediatric patients.

Contraindications

  • Condition1

Warnings

ConditionName:
See full prescribing information for complete Boxed Warning.
ConditionName:
  • Content
  • Description

Precautions

  • Description

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Clinical Trial Experience of Lanolin in the drug label.

Body as a Whole
Cardiovascular
Digestive
Endocrine
Hematologic and Lymphatic
Metabolic and Nutritional
Musculoskeletal
Neurologic
Respiratory
Skin and Hypersensitivy Reactions
Special Senses
Urogenital
Miscellaneous

Postmarketing Experience

There is limited information regarding Postmarketing Experience of Lanolin in the drug label.

Body as a Whole
Cardiovascular
Digestive
Endocrine
Hematologic and Lymphatic
Metabolic and Nutritional
Musculoskeletal
Neurologic
Respiratory
Skin and Hypersensitivy Reactions
Special Senses
Urogenital
Miscellaneous

Drug Interactions

  • Drug
  • Description

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA):

  • Pregnancy Category


Pregnancy Category (AUS):

  • Australian Drug Evaluation Committee (ADEC) Pregnancy Category

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Lanolin in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Lanolin during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Lanolin with respect to nursing mothers.

Pediatric Use

There is no FDA guidance on the use of Lanolin with respect to pediatric patients.

Geriatic Use

There is no FDA guidance on the use of Lanolin with respect to geriatric patients.

Gender

There is no FDA guidance on the use of Lanolin with respect to specific gender populations.

Race

There is no FDA guidance on the use of Lanolin with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Lanolin in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Lanolin in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Lanolin in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Lanolin in patients who are immunocompromised.

Administration and Monitoring

Administration

  • Oral
  • Intravenous

Monitoring

There is limited information regarding Monitoring of Lanolin in the drug label.

  • Description

IV Compatibility

There is limited information regarding IV Compatibility of Lanolin in the drug label.

Overdosage

Acute Overdose

Signs and Symptoms

  • Description

Management

  • Description

Chronic Overdose

There is limited information regarding Chronic Overdose of Lanolin in the drug label.

Pharmacology

There is limited information regarding Lanolin Pharmacology in the drug label.

Mechanism of Action

Structure

File:Lanolin01.png
This image is provided by the National Library of Medicine.

Pharmacodynamics

There is limited information regarding Pharmacodynamics of Lanolin in the drug label.

Pharmacokinetics

There is limited information regarding Pharmacokinetics of Lanolin in the drug label.

Nonclinical Toxicology

There is limited information regarding Nonclinical Toxicology of Lanolin in the drug label.

Clinical Studies

There is limited information regarding Clinical Studies of Lanolin in the drug label.

How Supplied

Storage

There is limited information regarding Lanolin Storage in the drug label.

Images

Drug Images

{{#ask: Page Name::Lanolin |?Pill Name |?Drug Name |?Pill Ingred |?Pill Imprint |?Pill Dosage |?Pill Color |?Pill Shape |?Pill Size (mm) |?Pill Scoring |?NDC |?Drug Author |format=template |template=DrugPageImages |mainlabel=- |sort=Pill Name }}

Package and Label Display Panel

{{#ask: Label Page::Lanolin |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}

Patient Counseling Information

There is limited information regarding Patient Counseling Information of Lanolin in the drug label.

Precautions with Alcohol

  • Alcohol-Lanolin interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

Look-Alike Drug Names

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

  1. ↑ Empty citation (help)
  2. ↑ "http://www.ismp.org". External link in |title= (help)

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