Minaprine: Difference between revisions
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{{Drugbox| | {{Drugbox| | ||
|IUPAC_name = 4-methyl-N-(2-morpholin-4-ylethyl)-6-phenylpyridazin-3-amine | |IUPAC_name = 4-methyl-N-(2-morpholin-4-ylethyl)-6-phenylpyridazin-3-amine | ||
| image = Minaprine. | | image = Minaprine Wiki Str.png | ||
| CAS_number=25905-77-5 | | CAS_number=25905-77-5 | ||
| ATC_prefix= | | ATC_prefix= | ||
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== Overview == | |||
'''Minaprine''' is an [[antidepressant]] drug which acts as a weak, short-acting [[monoamine oxidase inhibitor]], acting mainly at the MAO<sub>A</sub> subtype.<ref>Kan JP, Mouget-Goniot C, Worms P, Biziere K. Effect of the antidepressant minaprine on both forms of monoamine oxidase in the rat. ''Biochemical Pharmacology''. 1986 Mar 15;35(6):973-8. PMID 3954800</ref> It also has some [[acetylcholinesterase]] inhibitory activity.<ref>Contreras JM, Rival YM, Chayer S, Bourguignon JJ, Wermuth CG. Aminopyridazines as acetylcholinesterase inhibitors. ''Journal of Medicinal Chemistry''. 1999 Feb 25;42(4):730-41. PMID 10052979</ref> | '''Minaprine''' is an [[antidepressant]] drug which acts as a weak, short-acting [[monoamine oxidase inhibitor]], acting mainly at the MAO<sub>A</sub> subtype.<ref>Kan JP, Mouget-Goniot C, Worms P, Biziere K. Effect of the antidepressant minaprine on both forms of monoamine oxidase in the rat. ''Biochemical Pharmacology''. 1986 Mar 15;35(6):973-8. PMID 3954800</ref> It also has some [[acetylcholinesterase]] inhibitory activity.<ref>Contreras JM, Rival YM, Chayer S, Bourguignon JJ, Wermuth CG. Aminopyridazines as acetylcholinesterase inhibitors. ''Journal of Medicinal Chemistry''. 1999 Feb 25;42(4):730-41. PMID 10052979</ref> | ||
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[[Category:Drug]] | |||
[[Category:Antidepressants]] | [[Category:Antidepressants]] | ||
Revision as of 17:18, 13 April 2015
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| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
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| Formula | C17H22N4O |
| Molar mass | 298.383 g/mol |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Minaprine is an antidepressant drug which acts as a weak, short-acting monoamine oxidase inhibitor, acting mainly at the MAOA subtype.[1] It also has some acetylcholinesterase inhibitory activity.[2]
References
- ↑ Kan JP, Mouget-Goniot C, Worms P, Biziere K. Effect of the antidepressant minaprine on both forms of monoamine oxidase in the rat. Biochemical Pharmacology. 1986 Mar 15;35(6):973-8. PMID 3954800
- ↑ Contreras JM, Rival YM, Chayer S, Bourguignon JJ, Wermuth CG. Aminopyridazines as acetylcholinesterase inhibitors. Journal of Medicinal Chemistry. 1999 Feb 25;42(4):730-41. PMID 10052979
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