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{{ | '''Nuclear migration protein nudC''' is a [[protein]] that in humans is encoded by the ''NUDC'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: NUDC nuclear distribution gene C homolog (A. nidulans)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10726| accessdate = }}</ref> | ||
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== Interactions == | |||
< | NUDC has been shown to [[Protein-protein_interaction|interact]] with [[PLK1]]<ref name=pmid12852857>{{cite journal | vauthors = Zhou T, Aumais JP, Liu X, Yu-Lee LY, Erikson RL | title = A role for Plk1 phosphorylation of NudC in cytokinesis | journal = Developmental Cell | volume = 5 | issue = 1 | pages = 127–38 | date = Jul 2003 | pmid = 12852857 | doi = 10.1016/S1534-5807(03)00186-2 }}</ref> and [[PAFAH1B1]].<ref name=pmid9601647>{{cite journal | vauthors = Morris SM, Albrecht U, Reiner O, Eichele G, Yu-Lee LY | title = The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC | journal = Current Biology | volume = 8 | issue = 10 | pages = 603–6 | date = May 1998 | pmid = 9601647 | doi = 10.1016/S0960-9822(98)70232-5 }}</ref> | ||
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==References== | == References == | ||
{{reflist | {{reflist}} | ||
==Further reading== | |||
== Further reading == | |||
{{refbegin | 2}} | {{refbegin | 2}} | ||
* {{cite journal | vauthors = Morris SM, Albrecht U, Reiner O, Eichele G, Yu-Lee LY | title = The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC | journal = Current Biology | volume = 8 | issue = 10 | pages = 603–6 | date = May 1998 | pmid = 9601647 | doi = 10.1016/S0960-9822(98)70232-5 }} | |||
* {{cite journal | vauthors = Miller BA, Zhang MY, Gocke CD, De Souza C, Osmani AH, Lynch C, Davies J, Bell L, Osmani SA | title = A homolog of the fungal nuclear migration gene nudC is involved in normal and malignant human hematopoiesis | journal = Experimental Hematology | volume = 27 | issue = 4 | pages = 742–50 | date = Apr 1999 | pmid = 10210332 | doi = 10.1016/S0301-472X(98)00074-5 }} | |||
*{{cite journal | * {{cite journal | vauthors = Matsumoto N, Ledbetter DH | title = Molecular cloning and characterization of the human NUDC gene | journal = Human Genetics | volume = 104 | issue = 6 | pages = 498–504 | date = Jun 1999 | pmid = 10453739 | doi = 10.1007/s004390050994 }} | ||
*{{cite journal | * {{cite journal | vauthors = Hartley JL, Temple GF, Brasch MA | title = DNA cloning using in vitro site-specific recombination | journal = Genome Research | volume = 10 | issue = 11 | pages = 1788–95 | date = Nov 2000 | pmid = 11076863 | pmc = 310948 | doi = 10.1101/gr.143000 }} | ||
*{{cite journal | * {{cite journal | vauthors = Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A | title = Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs | journal = Genome Research | volume = 11 | issue = 3 | pages = 422–35 | date = Mar 2001 | pmid = 11230166 | pmc = 311072 | doi = 10.1101/gr.GR1547R }} | ||
*{{cite journal | * {{cite journal | vauthors = Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S | title = Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing | journal = EMBO Reports | volume = 1 | issue = 3 | pages = 287–92 | date = Sep 2000 | pmid = 11256614 | pmc = 1083732 | doi = 10.1093/embo-reports/kvd058 }} | ||
*{{cite journal | * {{cite journal | vauthors = Aumais JP, Tunstead JR, McNeil RS, Schaar BT, McConnell SK, Lin SH, Clark GD, Yu-Lee LY | title = NudC associates with Lis1 and the dynein motor at the leading pole of neurons | journal = The Journal of Neuroscience | volume = 21 | issue = 24 | pages = RC187 | date = Dec 2001 | pmid = 11734602 | doi = }} | ||
*{{cite journal | * {{cite journal | vauthors = Aumais JP, Williams SN, Luo W, Nishino M, Caldwell KA, Caldwell GA, Lin SH, Yu-Lee LY | title = Role for NudC, a dynein-associated nuclear movement protein, in mitosis and cytokinesis | journal = Journal of Cell Science | volume = 116 | issue = Pt 10 | pages = 1991–2003 | date = May 2003 | pmid = 12679384 | doi = 10.1242/jcs.00412 }} | ||
*{{cite journal | * {{cite journal | vauthors = Zhou T, Aumais JP, Liu X, Yu-Lee LY, Erikson RL | title = A role for Plk1 phosphorylation of NudC in cytokinesis | journal = Developmental Cell | volume = 5 | issue = 1 | pages = 127–38 | date = Jul 2003 | pmid = 12852857 | doi = 10.1016/S1534-5807(03)00186-2 }} | ||
*{{cite journal | * {{cite journal | vauthors = Lin SH, Nishino M, Luo W, Aumais JP, Galfione M, Kuang J, Yu-Lee LY | title = Inhibition of prostate tumor growth by overexpression of NudC, a microtubule motor-associated protein | journal = Oncogene | volume = 23 | issue = 14 | pages = 2499–506 | date = Apr 2004 | pmid = 14676831 | doi = 10.1038/sj.onc.1207343 }} | ||
* {{cite journal | vauthors = Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J, Ghidelli S, Hopf C, Huhse B, Mangano R, Michon AM, Schirle M, Schlegl J, Schwab M, Stein MA, Bauer A, Casari G, Drewes G, Gavin AC, Jackson DB, Joberty G, Neubauer G, Rick J, Kuster B, Superti-Furga G | title = A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway | journal = Nature Cell Biology | volume = 6 | issue = 2 | pages = 97–105 | date = Feb 2004 | pmid = 14743216 | doi = 10.1038/ncb1086 }} | |||
*{{cite journal | * {{cite journal | vauthors = Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A | title = From ORFeome to biology: a functional genomics pipeline | journal = Genome Research | volume = 14 | issue = 10B | pages = 2136–44 | date = Oct 2004 | pmid = 15489336 | pmc = 528930 | doi = 10.1101/gr.2576704 }} | ||
*{{cite journal | * {{cite journal | vauthors = Pan RM, Yang Y, Wei MX, Yu XB, Ge YC, Xu P | title = A microtubule associated protein (hNUDC) binds to the extracellular domain of thrombopoietin receptor (Mpl) | journal = Journal of Cellular Biochemistry | volume = 96 | issue = 4 | pages = 741–50 | date = Nov 2005 | pmid = 16088917 | doi = 10.1002/jcb.20573 }} | ||
*{{cite journal | * {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = Oct 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }} | ||
*{{cite journal | * {{cite journal | vauthors = Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S | title = The LIFEdb database in 2006 | journal = Nucleic Acids Research | volume = 34 | issue = Database issue | pages = D415-8 | date = Jan 2006 | pmid = 16381901 | pmc = 1347501 | doi = 10.1093/nar/gkj139 }} | ||
* {{cite journal | vauthors = Nishino M, Kurasawa Y, Evans R, Lin SH, Brinkley BR, Yu-Lee LY | title = NudC is required for Plk1 targeting to the kinetochore and chromosome congression | journal = Current Biology | volume = 16 | issue = 14 | pages = 1414–21 | date = Jul 2006 | pmid = 16860740 | doi = 10.1016/j.cub.2006.05.052 }} | |||
*{{cite journal | * {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | date = Nov 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 }} | ||
*{{cite journal | |||
*{{cite journal | |||
*{{cite journal | |||
*{{cite journal | |||
}} | |||
{{refend}} | {{refend}} | ||
{{PDB Gallery|geneid=10726}} | |||
{{ | {{gene-1-stub}} | ||
Latest revision as of 13:19, 5 September 2017
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External IDs | GeneCards: [1] | ||||||
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Species | Human | Mouse | |||||
Entrez |
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Ensembl |
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UniProt |
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RefSeq (mRNA) |
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RefSeq (protein) |
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Location (UCSC) | n/a | n/a | |||||
PubMed search | n/a | n/a | |||||
Wikidata | |||||||
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Nuclear migration protein nudC is a protein that in humans is encoded by the NUDC gene.[1]
Interactions
NUDC has been shown to interact with PLK1[2] and PAFAH1B1.[3]
References
- ↑ "Entrez Gene: NUDC nuclear distribution gene C homolog (A. nidulans)".
- ↑ Zhou T, Aumais JP, Liu X, Yu-Lee LY, Erikson RL (Jul 2003). "A role for Plk1 phosphorylation of NudC in cytokinesis". Developmental Cell. 5 (1): 127–38. doi:10.1016/S1534-5807(03)00186-2. PMID 12852857.
- ↑ Morris SM, Albrecht U, Reiner O, Eichele G, Yu-Lee LY (May 1998). "The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC". Current Biology. 8 (10): 603–6. doi:10.1016/S0960-9822(98)70232-5. PMID 9601647.
Further reading
- Morris SM, Albrecht U, Reiner O, Eichele G, Yu-Lee LY (May 1998). "The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC". Current Biology. 8 (10): 603–6. doi:10.1016/S0960-9822(98)70232-5. PMID 9601647.
- Miller BA, Zhang MY, Gocke CD, De Souza C, Osmani AH, Lynch C, Davies J, Bell L, Osmani SA (Apr 1999). "A homolog of the fungal nuclear migration gene nudC is involved in normal and malignant human hematopoiesis". Experimental Hematology. 27 (4): 742–50. doi:10.1016/S0301-472X(98)00074-5. PMID 10210332.
- Matsumoto N, Ledbetter DH (Jun 1999). "Molecular cloning and characterization of the human NUDC gene". Human Genetics. 104 (6): 498–504. doi:10.1007/s004390050994. PMID 10453739.
- Hartley JL, Temple GF, Brasch MA (Nov 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
- Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
- Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (Sep 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
- Aumais JP, Tunstead JR, McNeil RS, Schaar BT, McConnell SK, Lin SH, Clark GD, Yu-Lee LY (Dec 2001). "NudC associates with Lis1 and the dynein motor at the leading pole of neurons". The Journal of Neuroscience. 21 (24): RC187. PMID 11734602.
- Aumais JP, Williams SN, Luo W, Nishino M, Caldwell KA, Caldwell GA, Lin SH, Yu-Lee LY (May 2003). "Role for NudC, a dynein-associated nuclear movement protein, in mitosis and cytokinesis". Journal of Cell Science. 116 (Pt 10): 1991–2003. doi:10.1242/jcs.00412. PMID 12679384.
- Zhou T, Aumais JP, Liu X, Yu-Lee LY, Erikson RL (Jul 2003). "A role for Plk1 phosphorylation of NudC in cytokinesis". Developmental Cell. 5 (1): 127–38. doi:10.1016/S1534-5807(03)00186-2. PMID 12852857.
- Lin SH, Nishino M, Luo W, Aumais JP, Galfione M, Kuang J, Yu-Lee LY (Apr 2004). "Inhibition of prostate tumor growth by overexpression of NudC, a microtubule motor-associated protein". Oncogene. 23 (14): 2499–506. doi:10.1038/sj.onc.1207343. PMID 14676831.
- Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J, Ghidelli S, Hopf C, Huhse B, Mangano R, Michon AM, Schirle M, Schlegl J, Schwab M, Stein MA, Bauer A, Casari G, Drewes G, Gavin AC, Jackson DB, Joberty G, Neubauer G, Rick J, Kuster B, Superti-Furga G (Feb 2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nature Cell Biology. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216.
- Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (Oct 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
- Pan RM, Yang Y, Wei MX, Yu XB, Ge YC, Xu P (Nov 2005). "A microtubule associated protein (hNUDC) binds to the extracellular domain of thrombopoietin receptor (Mpl)". Journal of Cellular Biochemistry. 96 (4): 741–50. doi:10.1002/jcb.20573. PMID 16088917.
- Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (Jan 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
- Nishino M, Kurasawa Y, Evans R, Lin SH, Brinkley BR, Yu-Lee LY (Jul 2006). "NudC is required for Plk1 targeting to the kinetochore and chromosome congression". Current Biology. 16 (14): 1414–21. doi:10.1016/j.cub.2006.05.052. PMID 16860740.
- Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
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