NUPR1: Difference between revisions

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{{Underlinked|date=March 2014}}
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{{Infobox_gene}}
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'''Nuclear protein 1''' is a [[protein]] that in humans is encoded by the ''NUPR1'' [[gene]].<ref name="pmid9405444">{{cite journal | vauthors = Mallo GV, Fiedler F, Calvo EL, Ortiz EM, Vasseur S, Keim V, Morisset J, Iovanna JL | title = Cloning and expression of the rat p8 cDNA, a new gene activated in pancreas during the acute phase of pancreatitis, pancreatic development, and regeneration, and which promotes cellular growth | journal = J Biol Chem | volume = 272 | issue = 51 | pages = 32360–9 |date=Jan 1998 | pmid = 9405444 | pmc =  | doi =10.1074/jbc.272.51.32360 }}</ref><ref name="pmid10493524">{{cite journal | vauthors = Ree AH, Tvermyr M, Engebraaten O, Rooman M, Rosok O, Hovig E, Meza-Zepeda LA, Bruland OS, Fodstad O | title = Expression of a novel factor in human breast cancer cells with metastatic potential | journal = Cancer Res | volume = 59 | issue = 18 | pages = 4675–80 |date=Oct 1999 | pmid = 10493524 | pmc = | doi = }}</ref><ref name="pmid10092851">{{cite journal | vauthors = Vasseur S, Vidal Mallo G, Fiedler F, Bodeker H, Canepa E, Moreno S, Iovanna JL | title = Cloning and expression of the human p8, a nuclear protein with mitogenic activity | journal = Eur J Biochem | volume = 259 | issue = 3 | pages = 670–5 |date=Apr 1999 | pmid = 10092851 | pmc = | doi =10.1046/j.1432-1327.1999.00092.x }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: NUPR1 nuclear protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26471| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Nuclear protein 1
| HGNCid = 
| Symbol = NUPR1
| AltSymbols =; P8; COM1
| OMIM =
| ECnumber =
| Homologene = 8229
| MGIid = 1891834
  | GeneAtlas_image1 = PBB_GE_NUPR1_209230_s_at_tn.png
  | Function = {{GNF_GO|id=GO:0003674 |text = molecular_function}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006917 |text = induction of apoptosis}} {{GNF_GO|id=GO:0016049 |text = cell growth}}  
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 26471
    | Hs_Ensembl = ENSG00000176046
    | Hs_RefseqProtein = NP_001035948
    | Hs_RefseqmRNA = NM_001042483
    | Hs_GenLoc_db =
    | Hs_GenLoc_chr = 16
    | Hs_GenLoc_start = 28456163
    | Hs_GenLoc_end = 28457831
    | Hs_Uniprot = O60356
    | Mm_EntrezGene = 56312
    | Mm_Ensembl = ENSMUSG00000030717
    | Mm_RefseqmRNA = NM_019738
    | Mm_RefseqProtein = NP_062712
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 7
    | Mm_GenLoc_start = 126414397
    | Mm_GenLoc_end = 126416637
    | Mm_Uniprot = Q9D756
  }}
}}
'''Nuclear protein 1''', also known as '''NUPR1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: NUPR1 nuclear protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26471| accessdate = }}</ref>
 
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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Mallo GV, Fiedler F, Calvo EL, ''et al.'' |title=Cloning and expression of the rat p8 cDNA, a new gene activated in pancreas during the acute phase of pancreatitis, pancreatic development, and regeneration, and which promotes cellular growth. |journal=J. Biol. Chem. |volume=272 |issue= 51 |pages= 32360-9 |year= 1998 |pmid= 9405444 |doi=  }}
*{{cite journal   |vauthors=Loftus BJ, Kim UJ, Sneddon VP, etal |title=Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. |journal=Genomics |volume=60 |issue= 3 |pages= 295–308 |year= 1999 |pmid= 10493829 |doi= 10.1006/geno.1999.5927 }}
*{{cite journal  | author=Vasseur S, Vidal Mallo G, Fiedler F, ''et al.'' |title=Cloning and expression of the human p8, a nuclear protein with mitogenic activity. |journal=Eur. J. Biochem. |volume=259 |issue= 3 |pages= 670-5 |year= 1999 |pmid= 10092851 |doi=  }}
*{{cite journal   |vauthors=Hoffmeister A, Ropolo A, Vasseur S, etal |title=The HMG-I/Y-related protein p8 binds to p300 and Pax2 trans-activation domain-interacting protein to regulate the trans-activation activity of the Pax2A and Pax2B transcription factors on the glucagon gene promoter. |journal=J. Biol. Chem. |volume=277 |issue= 25 |pages= 22314–9 |year= 2002 |pmid= 11940591 |doi= 10.1074/jbc.M201657200 }}
*{{cite journal  | author=Ree AH, Tvermyr M, Engebraaten O, ''et al.'' |title=Expression of a novel factor in human breast cancer cells with metastatic potential. |journal=Cancer Res. |volume=59 |issue= 18 |pages= 4675-80 |year= 1999 |pmid= 10493524 |doi=  }}
*{{cite journal   |vauthors=Ree AH, Bratland A, Kroes RA, etal |title=Clinical and cell line specific expression profiles of a human gene identified in experimental central nervous system metastases. |journal=Anticancer Res. |volume=22 |issue= 4 |pages= 1949–57 |year= 2002 |pmid= 12174869 |doi=  }}
*{{cite journal  | author=Loftus BJ, Kim UJ, Sneddon VP, ''et al.'' |title=Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. |journal=Genomics |volume=60 |issue= 3 |pages= 295-308 |year= 1999 |pmid= 10493829 |doi= 10.1006/geno.1999.5927 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Hoffmeister A, Ropolo A, Vasseur S, ''et al.'' |title=The HMG-I/Y-related protein p8 binds to p300 and Pax2 trans-activation domain-interacting protein to regulate the trans-activation activity of the Pax2A and Pax2B transcription factors on the glucagon gene promoter. |journal=J. Biol. Chem. |volume=277 |issue= 25 |pages= 22314-9 |year= 2002 |pmid= 11940591 |doi= 10.1074/jbc.M201657200 }}
*{{cite journal   |vauthors=Suzuki Y, Yamashita R, Shirota M, etal |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604 | pmc=515316 }}
*{{cite journal | author=Ree AH, Bratland A, Kroes RA, ''et al.'' |title=Clinical and cell line specific expression profiles of a human gene identified in experimental central nervous system metastases. |journal=Anticancer Res. |volume=22 |issue= 4 |pages= 1949-57 |year= 2002 |pmid= 12174869 |doi=  }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Jiang WG, Davies G, Fodstad O |title=Com-1/P8 in oestrogen regulated growth of breast cancer cells, the ER-beta connection. |journal=Biochem. Biophys. Res. Commun. |volume=330 |issue= 1 |pages= 253–62 |year= 2005 |pmid= 15781258 |doi= 10.1016/j.bbrc.2005.02.157 }}
*{{cite journal | author=Suzuki Y, Yamashita R, Shirota M, ''et al.'' |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711-8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604 }}
*{{cite journal   |vauthors=Mao Y, Zhao Y, Zhou LF, etal |title=A novel gene mutation (1292 deletion) in a Chinese family with cerebral cavernous malformations. |journal=Neurosurgery |volume=56 |issue= 5 |pages= 1149–53; discussion 1149–53 |year= 2006 |pmid= 15854263 |doi= 10.1227/01.NEU.0000157967.67963.7A }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Ito Y, Yoshida H, Motoo Y, etal |title=Expression of p8 protein in medullary thyroid carcinoma. |journal=Anticancer Res. |volume=25 |issue= 5 |pages= 3419–23 |year= 2005 |pmid= 16101158 |doi=  }}
*{{cite journal  | author=Jiang WG, Davies G, Fodstad O |title=Com-1/P8 in oestrogen regulated growth of breast cancer cells, the ER-beta connection. |journal=Biochem. Biophys. Res. Commun. |volume=330 |issue= 1 |pages= 253-62 |year= 2005 |pmid= 15781258 |doi= 10.1016/j.bbrc.2005.02.157 }}
*{{cite journal   |vauthors=Valacco MP, Varone C, Malicet C, etal |title=Cell growth-dependent subcellular localization of p8. |journal=J. Cell. Biochem. |volume=97 |issue= 5 |pages= 1066–79 |year= 2006 |pmid= 16294328 |doi= 10.1002/jcb.20682 }}
*{{cite journal | author=Mao Y, Zhao Y, Zhou LF, ''et al.'' |title=A novel gene mutation (1292 deletion) in a Chinese family with cerebral cavernous malformations. |journal=Neurosurgery |volume=56 |issue= 5 |pages= 1149-53; discussion 1149-53 |year= 2006 |pmid= 15854263 |doi= }}
*{{cite journal   |vauthors=Malicet C, Hoffmeister A, Moreno S, etal |title=Interaction of the stress protein p8 with Jab1 is required for Jab1-dependent p27 nuclear-to-cytoplasm translocation. |journal=Biochem. Biophys. Res. Commun. |volume=339 |issue= 1 |pages= 284–9 |year= 2006 |pmid= 16300740 |doi= 10.1016/j.bbrc.2005.11.018 }}
*{{cite journal | author=Ito Y, Yoshida H, Motoo Y, ''et al.'' |title=Expression of p8 protein in medullary thyroid carcinoma. |journal=Anticancer Res. |volume=25 |issue= 5 |pages= 3419-23 |year= 2005 |pmid= 16101158 |doi=  }}
*{{cite journal   |vauthors=Malicet C, Giroux V, Vasseur S, etal |title=Regulation of apoptosis by the p8/prothymosin alpha complex. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 8 |pages= 2671–6 |year= 2006 |pmid= 16478804 |doi= 10.1073/pnas.0508955103 | pmc=1413786 }}
*{{cite journal | author=Valacco MP, Varone C, Malicet C, ''et al.'' |title=Cell growth-dependent subcellular localization of p8. |journal=J. Cell. Biochem. |volume=97 |issue= 5 |pages= 1066-79 |year= 2006 |pmid= 16294328 |doi= 10.1002/jcb.20682 }}
*{{cite journal  | vauthors=Malicet C, Dagorn JC, Neira JL, Iovanna JL |title=p8 and prothymosin alpha: unity is strength. |journal=Cell Cycle |volume=5 |issue= 8 |pages= 829–30 |year= 2006 |pmid= 16628001 |doi=  10.4161/cc.5.8.2686}}
*{{cite journal | author=Malicet C, Hoffmeister A, Moreno S, ''et al.'' |title=Interaction of the stress protein p8 with Jab1 is required for Jab1-dependent p27 nuclear-to-cytoplasm translocation. |journal=Biochem. Biophys. Res. Commun. |volume=339 |issue= 1 |pages= 284-9 |year= 2006 |pmid= 16300740 |doi= 10.1016/j.bbrc.2005.11.018 }}
*{{cite journal   |vauthors=Jiang WG, Davies G, Martin TA, etal |title=Com-1/p8 acts as a putative tumour suppressor in prostate cancer. |journal=Int. J. Mol. Med. |volume=18 |issue= 5 |pages= 981–6 |year= 2007 |pmid= 17016631 |doi=  10.3892/ijmm.18.5.981}}
*{{cite journal | author=Malicet C, Giroux V, Vasseur S, ''et al.'' |title=Regulation of apoptosis by the p8/prothymosin alpha complex. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 8 |pages= 2671-6 |year= 2006 |pmid= 16478804 |doi= 10.1073/pnas.0508955103 }}
*{{cite journal   |vauthors=Ishida M, Miyamoto M, Naitoh S, etal |title=The SYT-SSX fusion protein down-regulates the cell proliferation regulator COM1 in t(x;18) synovial sarcoma. |journal=Mol. Cell. Biol. |volume=27 |issue= 4 |pages= 1348–55 |year= 2007 |pmid= 17101797 |doi= 10.1128/MCB.00658-06 | pmc=1800732 }}
*{{cite journal  | author=Malicet C, Dagorn JC, Neira JL, Iovanna JL |title=p8 and prothymosin alpha: unity is strength. |journal=Cell Cycle |volume=5 |issue= 8 |pages= 829-30 |year= 2006 |pmid= 16628001 |doi=  }}
*{{cite journal  | vauthors=Goruppi S, Patten RD, Force T, Kyriakis JM |title=Helix-loop-helix protein p8, a transcriptional regulator required for cardiomyocyte hypertrophy and cardiac fibroblast matrix metalloprotease induction. |journal=Mol. Cell. Biol. |volume=27 |issue= 3 |pages= 993–1006 |year= 2007 |pmid= 17116693 |doi= 10.1128/MCB.00996-06 | pmc=1800682 }}
*{{cite journal | author=Jiang WG, Davies G, Martin TA, ''et al.'' |title=Com-1/p8 acts as a putative tumour suppressor in prostate cancer. |journal=Int. J. Mol. Med. |volume=18 |issue= 5 |pages= 981-6 |year= 2007 |pmid= 17016631 |doi=  }}
*{{cite journal | author=Ishida M, Miyamoto M, Naitoh S, ''et al.'' |title=The SYT-SSX fusion protein down-regulates the cell proliferation regulator COM1 in t(x;18) synovial sarcoma. |journal=Mol. Cell. Biol. |volume=27 |issue= 4 |pages= 1348-55 |year= 2007 |pmid= 17101797 |doi= 10.1128/MCB.00658-06 }}
*{{cite journal  | author=Goruppi S, Patten RD, Force T, Kyriakis JM |title=Helix-loop-helix protein p8, a transcriptional regulator required for cardiomyocyte hypertrophy and cardiac fibroblast matrix metalloprotease induction. |journal=Mol. Cell. Biol. |volume=27 |issue= 3 |pages= 993-1006 |year= 2007 |pmid= 17116693 |doi= 10.1128/MCB.00996-06 }}
}}
}}
{{refend}}
{{refend}}


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{{gene-16-stub}}

Latest revision as of 13:22, 5 September 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Nuclear protein 1 is a protein that in humans is encoded by the NUPR1 gene.[1][2][3][4]


References

  1. ↑ Mallo GV, Fiedler F, Calvo EL, Ortiz EM, Vasseur S, Keim V, Morisset J, Iovanna JL (Jan 1998). "Cloning and expression of the rat p8 cDNA, a new gene activated in pancreas during the acute phase of pancreatitis, pancreatic development, and regeneration, and which promotes cellular growth". J Biol Chem. 272 (51): 32360–9. doi:10.1074/jbc.272.51.32360. PMID 9405444.
  2. ↑ Ree AH, Tvermyr M, Engebraaten O, Rooman M, Rosok O, Hovig E, Meza-Zepeda LA, Bruland OS, Fodstad O (Oct 1999). "Expression of a novel factor in human breast cancer cells with metastatic potential". Cancer Res. 59 (18): 4675–80. PMID 10493524.
  3. ↑ Vasseur S, Vidal Mallo G, Fiedler F, Bodeker H, Canepa E, Moreno S, Iovanna JL (Apr 1999). "Cloning and expression of the human p8, a nuclear protein with mitogenic activity". Eur J Biochem. 259 (3): 670–5. doi:10.1046/j.1432-1327.1999.00092.x. PMID 10092851.
  4. ↑ "Entrez Gene: NUPR1 nuclear protein 1".

Further reading



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