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{{Underlinked|date=June 2016}}
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{{Infobox_gene}}
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'''Oligodendrocyte-myelin glycoprotein''' is a [[protein]] that in humans is encoded by the ''OMG'' [[gene]].<ref name="pmid1899288">{{cite journal | vauthors = Viskochil D, Cawthon R, O'Connell P, Xu GF, Stevens J, Culver M, Carey J, White R | title = The gene encoding the oligodendrocyte-myelin glycoprotein is embedded within the neurofibromatosis type 1 gene | journal = Mol Cell Biol | volume = 11 | issue = 2 | pages = 906–12 |date=Mar 1991 | pmid = 1899288 | pmc = 359746 | doi =  }}</ref><ref name="pmid2277079">{{cite journal | vauthors = Mikol DD, Alexakos MJ, Bayley CA, Lemons RS, Le Beau MM, Stefansson K | title = Structure and chromosomal localization of the gene for the oligodendrocyte-myelin glycoprotein | journal = J Cell Biol | volume = 111 | issue = 6 Pt 1 | pages = 2673–9 |date=Mar 1991 | pmid = 2277079 | pmc = 2116377 | doi =10.1083/jcb.111.6.2673 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: OMG oligodendrocyte myelin glycoprotein| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4974| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Oligodendrocyte myelin glycoprotein
| HGNCid = 8135
| Symbol = OMG
| AltSymbols =; OMGP
| OMIM = 164345
| ECnumber = 
| Homologene = 36099
| MGIid = 106586
| GeneAtlas_image1 = PBB_GE_OMG_207093_s_at_tn.png
| Function = {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0048503 |text = GPI anchor binding}}
| Component = {{GNF_GO|id=GO:0005624 |text = membrane fraction}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
  | Process = {{GNF_GO|id=GO:0007155 |text = cell adhesion}}  
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 4974
    | Hs_Ensembl = ENSG00000126861
    | Hs_RefseqProtein = NP_002535
    | Hs_RefseqmRNA = NM_002544
    | Hs_GenLoc_db =
    | Hs_GenLoc_chr = 17
    | Hs_GenLoc_start = 26645795
    | Hs_GenLoc_end = 26648481
    | Hs_Uniprot = P23515
    | Mm_EntrezGene = 18377
    | Mm_Ensembl = ENSMUSG00000049612
    | Mm_RefseqmRNA = NM_019409
    | Mm_RefseqProtein = NP_062282
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 11
    | Mm_GenLoc_start = 79317547
    | Mm_GenLoc_end = 79320214
    | Mm_Uniprot = Q3UVV3
  }}
}}
'''Oligodendrocyte myelin glycoprotein''', also known as '''OMG''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OMG oligodendrocyte myelin glycoprotein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4974| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Mikol DD, Gulcher JR, Stefansson K |title=The oligodendrocyte-myelin glycoprotein belongs to a distinct family of proteins and contains the HNK-1 carbohydrate. |journal=J. Cell Biol. |volume=110 |issue= 2 |pages= 471-9 |year= 1990 |pmid= 1688857 |doi= }}
*{{cite journal  | vauthors=Mikol DD, Gulcher JR, Stefansson K |title=The oligodendrocyte-myelin glycoprotein belongs to a distinct family of proteins and contains the HNK-1 carbohydrate. |journal=J. Cell Biol. |volume=110 |issue= 2 |pages= 471–9 |year= 1990 |pmid= 1688857 |doi=10.1083/jcb.110.2.471 | pmc=2116011 }}
*{{cite journal  | author=Viskochil D, Cawthon R, O'Connell P, ''et al.'' |title=The gene encoding the oligodendrocyte-myelin glycoprotein is embedded within the neurofibromatosis type 1 gene. |journal=Mol. Cell. Biol. |volume=11 |issue= 2 |pages= 906-12 |year= 1991 |pmid= 1899288 |doi=  }}
*{{cite journal  | vauthors=Mikol DD, Stefansson K |title=A phosphatidylinositol-linked peanut agglutinin-binding glycoprotein in central nervous system myelin and on oligodendrocytes. |journal=J. Cell Biol. |volume=106 |issue= 4 |pages= 1273–9 |year= 1988 |pmid= 3283151 |doi=10.1083/jcb.106.4.1273  | pmc=2115011 }}
*{{cite journal | author=Mikol DD, Alexakos MJ, Bayley CA, ''et al.'' |title=Structure and chromosomal localization of the gene for the oligodendrocyte-myelin glycoprotein. |journal=J. Cell Biol. |volume=111 |issue= 6 Pt 1 |pages= 2673-9 |year= 1991 |pmid= 2277079 |doi=  }}
*{{cite journal  | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
*{{cite journal  | author=Mikol DD, Stefansson K |title=A phosphatidylinositol-linked peanut agglutinin-binding glycoprotein in central nervous system myelin and on oligodendrocytes. |journal=J. Cell Biol. |volume=106 |issue= 4 |pages= 1273-9 |year= 1988 |pmid= 3283151 |doi=  }}
*{{cite journal   |vauthors=Mikol DD, Rongnoparut P, Allwardt BA, etal |title=The oligodendrocyte-myelin glycoprotein of mouse: primary structure and gene structure |journal=Genomics |volume=17 |issue= 3 |pages= 604–10 |year= 1993 |pmid= 8244377 |doi= 10.1006/geno.1993.1379 }}
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal   |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 }}
*{{cite journal | author=Mikol DD, Rongnoparut P, Allwardt BA, ''et al.'' |title=The oligodendrocyte-myelin glycoprotein of mouse: primary structure and gene structure. |journal=Genomics |volume=17 |issue= 3 |pages= 604-10 |year= 1993 |pmid= 8244377 |doi= 10.1006/geno.1993.1379 }}
*{{cite journal   |vauthors=Wang KC, Koprivica V, Kim JA, etal |title=Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth |journal=Nature |volume=417 |issue= 6892 |pages= 941–4 |year= 2002 |pmid= 12068310 |doi= 10.1038/nature00867 }}
*{{cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Wang KC, Koprivica V, Kim JA, ''et al.'' |title=Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth. |journal=Nature |volume=417 |issue= 6892 |pages= 941-4 |year= 2002 |pmid= 12068310 |doi= 10.1038/nature00867 }}
*{{cite journal   |vauthors=Vourc'h P, Moreau T, Arbion F, etal |title=Oligodendrocyte myelin glycoprotein growth inhibition function requires its conserved leucine-rich repeat domain, not its glycosylphosphatidyl-inositol anchor |journal=J. Neurochem. |volume=85 |issue= 4 |pages= 889–97 |year= 2003 |pmid= 12716421 |doi=10.1046/j.1471-4159.2003.01764.x }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Vourc'h P, Moreau T, Arbion F, ''et al.'' |title=Oligodendrocyte myelin glycoprotein growth inhibition function requires its conserved leucine-rich repeat domain, not its glycosylphosphatidyl-inositol anchor. |journal=J. Neurochem. |volume=85 |issue= 4 |pages= 889-97 |year= 2003 |pmid= 12716421 |doi=  }}
*{{cite journal   |vauthors=Venturin M, Moncini S, Villa V, etal |title=Mutations and novel polymorphisms in coding regions and UTRs of CDK5R1 and OMG genes in patients with non-syndromic mental retardation |journal=Neurogenetics |volume=7 |issue= 1 |pages= 59–66 |year= 2007 |pmid= 16425041 |doi= 10.1007/s10048-005-0026-9 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Douglas J, Cilliers D, Coleman K, etal |title=Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth |journal=Nat. Genet. |volume=39 |issue= 8 |pages= 963–5 |year= 2007 |pmid= 17632510 |doi= 10.1038/ng2083 }}
*{{cite journal | author=Venturin M, Moncini S, Villa V, ''et al.'' |title=Mutations and novel polymorphisms in coding regions and UTRs of CDK5R1 and OMG genes in patients with non-syndromic mental retardation. |journal=Neurogenetics |volume=7 |issue= 1 |pages= 59-66 |year= 2007 |pmid= 16425041 |doi= 10.1007/s10048-005-0026-9 }}
*{{cite journal | author=Douglas J, Cilliers D, Coleman K, ''et al.'' |title=Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth. |journal=Nat. Genet. |volume=39 |issue= 8 |pages= 963-5 |year= 2007 |pmid= 17632510 |doi= 10.1038/ng2083 }}
}}
}}
{{refend}}
{{refend}}


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Revision as of 00:24, 7 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

n/a

n/a

RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Oligodendrocyte-myelin glycoprotein is a protein that in humans is encoded by the OMG gene.[1][2][3]


References

  1. ↑ Viskochil D, Cawthon R, O'Connell P, Xu GF, Stevens J, Culver M, Carey J, White R (Mar 1991). "The gene encoding the oligodendrocyte-myelin glycoprotein is embedded within the neurofibromatosis type 1 gene". Mol Cell Biol. 11 (2): 906–12. PMC 359746. PMID 1899288.
  2. ↑ Mikol DD, Alexakos MJ, Bayley CA, Lemons RS, Le Beau MM, Stefansson K (Mar 1991). "Structure and chromosomal localization of the gene for the oligodendrocyte-myelin glycoprotein". J Cell Biol. 111 (6 Pt 1): 2673–9. doi:10.1083/jcb.111.6.2673. PMC 2116377. PMID 2277079.
  3. ↑ "Entrez Gene: OMG oligodendrocyte myelin glycoprotein".

Further reading



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