PDXK: Difference between revisions

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Revision as of 17:53, 7 September 2017

Pyridoxal kinase is an enzyme that in humans is encoded by the PDXK gene.^[1]^[2]

The protein encoded by this gene phosphorylates vitamin B₆, a step required for the conversion of vitamin B₆ to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.^[2]

References

↑ Hanna MC, Turner AJ, Kirkness EF (May 1997). "Human pyridoxal kinase. cDNA cloning, expression, and modulation by ligands of the benzodiazepine receptor". J Biol Chem. 272 (16): 10756–60. doi:10.1074/jbc.272.16.10756. PMID 9099727.
↑ ^2.0 ^2.1 "Entrez Gene: PDXK pyridoxal (pyridoxine, vitamin B₆) kinase".

Chern CJ, Beutler E (1976). "Biochemical and electrophoretic studies of erythrocyte pyridoxine kinase in white and black Americans". Am. J. Hum. Genet. 28 (1): 9–17. PMC 1684914. PMID 2009.
Merrill AH, Henderson JM, Wang E, et al. (1984). "Metabolism of vitamin B-6 by human liver". J. Nutr. 114 (9): 1664–74. PMID 6088736.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Zhang Z, Smith E, Surowiec SM, et al. (1993). "Synthesis of N-(4'-pyridoxyl)sphingosine and its uptake and metabolism by isolated cells". Membrane biochemistry. 10 (1): 53–9. doi:10.3109/09687689309150252. PMID 8510562.
Lainé-Cessac P, Cailleux A, Allain P (1997). "Mechanisms of the inhibition of human erythrocyte pyridoxal kinase by drugs". Biochem. Pharmacol. 54 (8): 863–70. doi:10.1016/S0006-2952(97)00252-9. PMID 9354586.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Hattori M, Fujiyama A, Taylor TD, et al. (2000). "The DNA sequence of human chromosome 21". Nature. 405 (6784): 311–9. doi:10.1038/35012518. PMID 10830953.
Lee HS, Moon BJ, Choi SY, Kwon OS (2001). "Human pyridoxal kinase: overexpression and properties of the recombinant enzyme". Mol. Cells. 10 (4): 452–9. PMID 10987144.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Shin JH, Weitzdoerfer R, Fountoulakis M, Lubec G (2004). "Expression of cystathionine beta-synthase, pyridoxal kinase, and ES1 protein homolog (mitochondrial precursor) in fetal Down syndrome brain". Neurochem. Int. 45 (1): 73–9. doi:10.1016/j.neuint.2003.12.004. PMID 15082224.
Fang X, Zhou ZM, Lu L, et al. (2004). "Expression of a novel pyridoxal kinase mRNA splice variant, PKH-T, in human testis". Asian J. Androl. 6 (2): 83–91. PMID 15154080.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wang L, Zhu YF, Guo XJ, et al. (2006). "A two-dimensional electrophoresis reference map of human ovary". J. Mol. Med. 83 (10): 812–21. doi:10.1007/s00109-005-0676-y. PMID 16021519.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Flanagan JM, Beutler E (2006). "The genetic basis of human erythrocyte pyridoxal kinase activity variation". Haematologica. 91 (6): 801–4. PMID 16704963.
Hu YH, Warnatz HJ, Vanhecke D, et al. (2006). "Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins". BMC Genomics. 7: 155. doi:10.1186/1471-2164-7-155. PMC 1526728. PMID 16780588.
Musayev FN, di Salvo ML, Ko TP, et al. (2007). "Crystal Structure of human pyridoxal kinase: Structural basis of M+ and M2+ activation". Protein Sci. 16 (10): 2184–94. doi:10.1110/ps.073022107. PMC 2204131. PMID 17766369.

This article on a gene on human chromosome 21 is a stub. You can help Wikipedia by expanding it.

[pmid9099727-1] Hanna MC, Turner AJ, Kirkness EF (May 1997). "Human pyridoxal kinase. cDNA cloning, expression, and modulation by ligands of the benzodiazepine receptor". J Biol Chem. 272 (16): 10756–60. doi:10.1074/jbc.272.16.10756. PMID 9099727.

[entrez-2] 2.0 ^2.1 "Entrez Gene: PDXK pyridoxal (pyridoxine, vitamin B₆) kinase".

[1]

[2]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Underlinked|date=March 2014}}
-{{PBB_Controls
+{{Infobox_gene}}
-| update_page = yes
+'''Pyridoxal kinase''' is an [[enzyme]] that in humans is encoded by the ''PDXK'' [[gene]].<ref name="pmid9099727">{{cite journal |vauthors=Hanna MC, Turner AJ, Kirkness EF | title = Human pyridoxal kinase. cDNA cloning, expression, and modulation by ligands of the benzodiazepine receptor | journal = J Biol Chem | volume = 272 | issue = 16 | pages = 10756–60 |date=May 1997 | pmid = 9099727 | pmc =  | doi =10.1074/jbc.272.16.10756  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PDXK pyridoxal (pyridoxine, vitamin B<sub>6</sub>) kinase| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8566| accessdate = }}</ref>
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-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{GNF_Protein_box
- | image = PBB_Protein_PDXK_image.jpg
- | image_source = [[Protein_Data_Bank|PDB]] rendering based on 2ajp.
- | PDB = {{PDB2|2ajp}}, {{PDB2|2f7k}}
- | Name = Pyridoxal (pyridoxine, vitamin B6) kinase
- | HGNCid = 8819
- | Symbol = PDXK
- | AltSymbols =; C21orf97; PKH; PNK
- | OMIM = 179020
- | ECnumber =
- | Homologene = 2731
- | MGIid = 1351869
-  | GeneAtlas_image1 = PBB_GE_PDXK_202671_s_at_tn.png
- | GeneAtlas_image2 = PBB_GE_PDXK_218018_at_tn.png
- | GeneAtlas_image3 = PBB_GE_PDXK_218019_s_at_tn.png
-  | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0008478 |text = pyridoxal kinase activity}} {{GNF_GO|id=GO:0016740 |text = transferase activity}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
- | Component =
- | Process =
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 8566
-    | Hs_Ensembl = ENSG00000160209
-    | Hs_RefseqProtein = NP_003672
-    | Hs_RefseqmRNA = NM_003681
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 21
-    | Hs_GenLoc_start = 43963406
-    | Hs_GenLoc_end = 44006608
-    | Hs_Uniprot = O00764
-    | Mm_EntrezGene = 216134
-    | Mm_Ensembl = ENSMUSG00000032788
-    | Mm_RefseqmRNA = NM_172134
-    | Mm_RefseqProtein = NP_742146
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 10
-    | Mm_GenLoc_start = 77842083
-    | Mm_GenLoc_end = 77868104
-    | Mm_Uniprot = Q8K183
-  }}
-}}
-'''Pyridoxal (pyridoxine, vitamin B6) kinase''', also known as '''PDXK''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: PDXK pyridoxal (pyridoxine, vitamin B6) kinase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8566| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
 {{PBB_Summary
 | section_title =
-| summary_text = The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.<ref name="entrez">{{cite web | title = Entrez Gene: PDXK pyridoxal (pyridoxine, vitamin B6) kinase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8566| accessdate = }}</ref>
+| summary_text = The protein encoded by this gene phosphorylates vitamin B<sub>6</sub>, a step required for the conversion of vitamin B<sub>6</sub> to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.<ref name="entrez"/>
 }}
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Chern CJ, Beutler E |title=Biochemical and electrophoretic studies of erythrocyte pyridoxine kinase in white and black Americans. |journal=Am. J. Hum. Genet. |volume=28 |issue= 01 |pages= 9-17 |year= 1976 |pmid= 2009 |doi=  }}
+*{{cite journal  |vauthors=Chern CJ, Beutler E |title=Biochemical and electrophoretic studies of erythrocyte pyridoxine kinase in white and black Americans |journal=Am. J. Hum. Genet. |volume=28 |issue= 1 |pages= 9–17 |year= 1976 |pmid= 2009 | pmc=1684914  }}
-*{{cite journal  | author=Merrill AH, Henderson JM, Wang E, ''et al.'' |title=Metabolism of vitamin B-6 by human liver. |journal=J. Nutr. |volume=114 |issue= 9 |pages= 1664-74 |year= 1984 |pmid= 6088736 |doi=  }}
+*{{cite journal  | author=Merrill AH |title=Metabolism of vitamin B-6 by human liver |journal=J. Nutr. |volume=114 |issue= 9 |pages= 1664–74 |year= 1984 |pmid= 6088736 |doi=  |name-list-format=vanc| author2=Henderson JM  | author3=Wang E  | display-authors=3  | last4=McDonald  | first4=BW  | last5=Millikan  | first5=WJ  }}
-*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
+*{{cite journal  |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
-*{{cite journal  | author=Zhang Z, Smith E, Surowiec SM, ''et al.'' |title=Synthesis of N-(4'-pyridoxyl)sphingosine and its uptake and metabolism by isolated cells. |journal=Membrane biochemistry |volume=10 |issue= 1 |pages= 53-9 |year= 1993 |pmid= 8510562 |doi=  }}
+*{{cite journal  | author=Zhang Z |title=Synthesis of N-(4'-pyridoxyl)sphingosine and its uptake and metabolism by isolated cells |journal=Membrane biochemistry |volume=10 |issue= 1 |pages= 53–9 |year= 1993 |pmid= 8510562 |doi=10.3109/09687689309150252  |name-list-format=vanc| author2=Smith E  | author3=Surowiec SM  | display-authors=3  | last4=Merrill  | first4=Alfred H.  | last5=McCormick  | first5=Donald B.  }}
-*{{cite journal  | author=Hanna MC, Turner AJ, Kirkness EF |title=Human pyridoxal kinase. cDNA cloning, expression, and modulation by ligands of the benzodiazepine receptor. |journal=J. Biol. Chem. |volume=272 |issue= 16 |pages= 10756-60 |year= 1997 |pmid= 9099727 |doi=  }}
+*{{cite journal  |vauthors=Lainé-Cessac P, Cailleux A, Allain P |title=Mechanisms of the inhibition of human erythrocyte pyridoxal kinase by drugs |journal=Biochem. Pharmacol. |volume=54 |issue= 8 |pages= 863–70 |year= 1997 |pmid= 9354586 |doi=10.1016/S0006-2952(97)00252-9  }}
-*{{cite journal  | author=Lainé-Cessac P, Cailleux A, Allain P |title=Mechanisms of the inhibition of human erythrocyte pyridoxal kinase by drugs. |journal=Biochem. Pharmacol. |volume=54 |issue= 8 |pages= 863-70 |year= 1997 |pmid= 9354586 |doi=  }}
+*{{cite journal  | author=Suzuki Y |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3  |name-list-format=vanc| author2=Yoshitomo-Nakagawa K  | author3=Maruyama K  | display-authors=3  | last4=Suyama  | first4=A  | last5=Sugano  | first5=S  }}
-*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
+*{{cite journal  | author=Hattori M |title=The DNA sequence of human chromosome 21 |journal=Nature |volume=405 |issue= 6784 |pages= 311–9 |year= 2000 |pmid= 10830953 |doi= 10.1038/35012518  |name-list-format=vanc| author2=Fujiyama A  | author3=Taylor TD  | display-authors=3  | last4=Taylor  | first4=T. D.  | last5=Watanabe  | first5=H.  | last6=Yada  | first6=T.  | last7=Park  | first7=H.-S.  | last8=Toyoda  | first8=A.  | last9=Ishii  | first9=K. }}
-*{{cite journal  | author=Hattori M, Fujiyama A, Taylor TD, ''et al.'' |title=The DNA sequence of human chromosome 21. |journal=Nature |volume=405 |issue= 6784 |pages= 311-9 |year= 2000 |pmid= 10830953 |doi= 10.1038/35012518 }}
+*{{cite journal  |vauthors=Lee HS, Moon BJ, Choi SY, Kwon OS |title=Human pyridoxal kinase: overexpression and properties of the recombinant enzyme |journal=Mol. Cells |volume=10 |issue= 4 |pages= 452–9 |year= 2001 |pmid= 10987144 |doi=  }}
-*{{cite journal  | author=Lee HS, Moon BJ, Choi SY, Kwon OS |title=Human pyridoxal kinase: overexpression and properties of the recombinant enzyme. |journal=Mol. Cells |volume=10 |issue= 4 |pages= 452-9 |year= 2001 |pmid= 10987144 |doi=  }}
+*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal  | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285  |name-list-format=vanc| author2=Suzuki Y  | author3=Nishikawa T  | display-authors=3  | last4=Otsuki  | first4=Tetsuji  | last5=Sugiyama  | first5=Tomoyasu  | last6=Irie  | first6=Ryotaro  | last7=Wakamatsu  | first7=Ai  | last8=Hayashi  | first8=Koji  | last9=Sato  | first9=Hiroyuki }}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
+*{{cite journal  |vauthors=Shin JH, Weitzdoerfer R, Fountoulakis M, Lubec G |title=Expression of cystathionine beta-synthase, pyridoxal kinase, and ES1 protein homolog (mitochondrial precursor) in fetal Down syndrome brain |journal=Neurochem. Int. |volume=45 |issue= 1 |pages= 73–9 |year= 2004 |pmid= 15082224 |doi= 10.1016/j.neuint.2003.12.004 }}
-*{{cite journal  | author=Shin JH, Weitzdoerfer R, Fountoulakis M, Lubec G |title=Expression of cystathionine beta-synthase, pyridoxal kinase, and ES1 protein homolog (mitochondrial precursor) in fetal Down syndrome brain. |journal=Neurochem. Int. |volume=45 |issue= 1 |pages= 73-9 |year= 2004 |pmid= 15082224 |doi= 10.1016/j.neuint.2003.12.004 }}
+*{{cite journal  | author=Fang X |title=Expression of a novel pyridoxal kinase mRNA splice variant, PKH-T, in human testis |journal=Asian J. Androl. |volume=6 |issue= 2 |pages= 83–91 |year= 2004 |pmid= 15154080 |doi=  |name-list-format=vanc| author2=Zhou ZM  | author3=Lu L  | display-authors=3  | last4=Yin  | first4=LL  | last5=Li  | first5=JM  | last6=Zhen  | first6=Y  | last7=Wang  | first7=H  | last8=Sha  | first8=JH  }}
-*{{cite journal  | author=Fang X, Zhou ZM, Lu L, ''et al.'' |title=Expression of a novel pyridoxal kinase mRNA splice variant, PKH-T, in human testis. |journal=Asian J. Androl. |volume=6 |issue= 2 |pages= 83-91 |year= 2004 |pmid= 15154080 |doi=  }}
+*{{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal  | author=Wang L |title=A two-dimensional electrophoresis reference map of human ovary |journal=J. Mol. Med. |volume=83 |issue= 10 |pages= 812–21 |year= 2006 |pmid= 16021519 |doi= 10.1007/s00109-005-0676-y  |name-list-format=vanc| author2=Zhu YF  | author3=Guo XJ  | display-authors=3  | last4=Huo  | first4=Ran  | last5=Ma  | first5=Xiang  | last6=Lin  | first6=Min  | last7=Zhou  | first7=Zuo-Min  | last8=Sha  | first8=Jia-Hao }}
-*{{cite journal  | author=Wang L, Zhu YF, Guo XJ, ''et al.'' |title=A two-dimensional electrophoresis reference map of human ovary. |journal=J. Mol. Med. |volume=83 |issue= 10 |pages= 812-21 |year= 2006 |pmid= 16021519 |doi= 10.1007/s00109-005-0676-y }}
+*{{cite journal  | author=Kimura K |title=Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406  | pmc=1356129  |name-list-format=vanc| author2=Wakamatsu A  | author3=Suzuki Y  | display-authors=3  | last4=Ota  | first4=T  | last5=Nishikawa  | first5=T  | last6=Yamashita  | first6=R  | last7=Yamamoto  | first7=J  | last8=Sekine  | first8=M  | last9=Tsuritani  | first9=K }}
-*{{cite journal  | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
+*{{cite journal  |vauthors=Flanagan JM, Beutler E |title=The genetic basis of human erythrocyte pyridoxal kinase activity variation |journal=Haematologica |volume=91 |issue= 6 |pages= 801–4 |year= 2006 |pmid= 16704963 |doi=  }}
-*{{cite journal  | author=Flanagan JM, Beutler E |title=The genetic basis of human erythrocyte pyridoxal kinase activity variation. |journal=Haematologica |volume=91 |issue= 6 |pages= 801-4 |year= 2006 |pmid= 16704963 |doi=  }}
+*{{cite journal  | author=Hu YH |title=Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins |journal=BMC Genomics |volume=7|pages= 155 |year= 2006 |pmid= 16780588 |doi= 10.1186/1471-2164-7-155  | pmc=1526728  |name-list-format=vanc| author2=Warnatz HJ  | author3=Vanhecke D  | display-authors=3  | last4=Wagner  | first4=Florian  | last5=Fiebitz  | first5=Andrea  | last6=Thamm  | first6=Sabine  | last7=Kahlem  | first7=Pascal  | last8=Lehrach  | first8=Hans  | last9=Yaspo  | first9=Marie-Laure }}
-*{{cite journal  | author=Hu YH, Warnatz HJ, Vanhecke D, ''et al.'' |title=Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins. |journal=BMC Genomics |volume=7 |issue=  |pages= 155 |year= 2006 |pmid= 16780588 |doi= 10.1186/1471-2164-7-155 }}
+*{{cite journal  | author=Musayev FN |title=Crystal Structure of human pyridoxal kinase: Structural basis of M+ and M2+ activation |journal=Protein Sci. |volume=16 |issue= 10 |pages= 2184–94 |year= 2007 |pmid= 17766369 |doi= 10.1110/ps.073022107  | pmc=2204131  |name-list-format=vanc| author2=di Salvo ML  | author3=Ko TP  | display-authors=3  | last4=Gandhi  | first4=Amit K.  | last5=Goswami  | first5=Ashwini  | last6=Schirch  | first6=Verne  | last7=Safo  | first7=Martin K. }}
-*{{cite journal  | author=Musayev FN, di Salvo ML, Ko TP, ''et al.'' |title=Crystal Structure of human pyridoxal kinase: structural basis of M(+) and M(2+) activation. |journal=Protein Sci. |volume=16 |issue= 10 |pages= 2184-94 |year= 2007 |pmid= 17766369 |doi= 10.1110/ps.073022107 }}
 }}
 {{refend}}
+{{PDB Gallery|geneid=8566}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
+| update_summary = yes
+| update_citations = yes
+}}
 {{gene-21-stub}}
-{{WikiDoc Sources}}

PDXK: Difference between revisions

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