RAB21: Difference between revisions

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Revision as of 08:45, 10 September 2017

Ras-related protein Rab-21 is a protein that in humans is encoded by the RAB21 gene.^[1]^[2]^[3]^[4]

References

↑ Opdam FJ, Kamps G, Croes H, van Bokhoven H, Ginsel LA, Fransen JA (Oct 2000). "Expression of Rab small GTPases in epithelial Caco-2 cells: Rab21 is an apically located GTP-binding protein in polarised intestinal epithelial cells". Eur J Cell Biol. 79 (5): 308–16. doi:10.1078/S0171-9335(04)70034-5. PMID 10887961.
↑ Pereira-Leal JB, Seabra MC (Nov 2001). "Evolution of the Rab family of small GTP-binding proteins". J Mol Biol. 313 (4): 889–901. doi:10.1006/jmbi.2001.5072. PMID 11697911.
↑ Pellinen T, Arjonen A, Vuoriluoto K, Kallio K, Fransen JA, Ivaska J (Jun 2006). "Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins". J Cell Biol. 173 (5): 767–80. doi:10.1083/jcb.200509019. PMC 2063892. PMID 16754960.
↑ "Entrez Gene: RAB21 RAB21, member RAS oncogene family".

Nagase T, Miyajima N, Tanaka A, et al. (1995). "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 2 (1): 37–43. doi:10.1093/dnares/2.1.37. PMID 7788527.
Bao S, Zhu J, Garvey WT (1999). "Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects". Horm. Metab. Res. 30 (11): 656–62. doi:10.1055/s-2007-978953. PMID 9918381.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it.

[pmid10887961-1] Opdam FJ, Kamps G, Croes H, van Bokhoven H, Ginsel LA, Fransen JA (Oct 2000). "Expression of Rab small GTPases in epithelial Caco-2 cells: Rab21 is an apically located GTP-binding protein in polarised intestinal epithelial cells". Eur J Cell Biol. 79 (5): 308–16. doi:10.1078/S0171-9335(04)70034-5. PMID 10887961.

[pmid11697911-2] Pereira-Leal JB, Seabra MC (Nov 2001). "Evolution of the Rab family of small GTP-binding proteins". J Mol Biol. 313 (4): 889–901. doi:10.1006/jmbi.2001.5072. PMID 11697911.

[pmid16754960-3] Pellinen T, Arjonen A, Vuoriluoto K, Kallio K, Fransen JA, Ivaska J (Jun 2006). "Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins". J Cell Biol. 173 (5): 767–80. doi:10.1083/jcb.200509019. PMC 2063892. PMID 16754960.

[entrez-4] "Entrez Gene: RAB21 RAB21, member RAS oncogene family".

[1]

[2]

[3]

[4]

@@ Line 1: / Line 1: @@
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+{{Underlinked|date=June 2016}}
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+{{Infobox_gene}}
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+'''Ras-related protein Rab-21''' is a [[protein]] that in humans is encoded by the ''RAB21'' [[gene]].<ref name="pmid10887961">{{cite journal | vauthors = Opdam FJ, Kamps G, Croes H, van Bokhoven H, Ginsel LA, Fransen JA | title = Expression of Rab small GTPases in epithelial Caco-2 cells: Rab21 is an apically located GTP-binding protein in polarised intestinal epithelial cells | journal = Eur J Cell Biol | volume = 79 | issue = 5 | pages = 308–16 |date=Oct 2000 | pmid = 10887961 | pmc =  | doi =10.1078/S0171-9335(04)70034-5  }}</ref><ref name="pmid11697911">{{cite journal | vauthors = Pereira-Leal JB, Seabra MC | title = Evolution of the Rab family of small GTP-binding proteins | journal = J Mol Biol | volume = 313 | issue = 4 | pages = 889–901 |date=Nov 2001 | pmid = 11697911 | pmc =  | doi = 10.1006/jmbi.2001.5072 }}</ref><ref name="pmid16754960">{{cite journal | vauthors = Pellinen T, Arjonen A, Vuoriluoto K, Kallio K, Fransen JA, Ivaska J | title = Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins | journal = J Cell Biol | volume = 173 | issue = 5 | pages = 767–80 |date=Jun 2006 | pmid = 16754960 | pmc = 2063892 | doi = 10.1083/jcb.200509019 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RAB21 RAB21, member RAS oncogene family| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23011| accessdate = }}</ref>
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- | image = PBB_Protein_RAB21_image.jpg
- | image_source = [[Protein_Data_Bank|PDB]] rendering based on 1yzt.
- | PDB = {{PDB2|1yzt}}, {{PDB2|1yzu}}, {{PDB2|1z08}}, {{PDB2|1z0i}}, {{PDB2|2ot3}}
- | Name = RAB21, member RAS oncogene family
- | HGNCid = 18263
- | Symbol = RAB21
- | AltSymbols =; KIAA0118
- | OMIM =
- | ECnumber =
- | Homologene = 8991
- | MGIid = 894308
- | GeneAtlas_image1 = PBB_GE_RAB21_203885_at_tn.png
-  | GeneAtlas_image2 = PBB_GE_RAB21_gnf1h10035_s_at_tn.png
-  | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0005525 |text = GTP binding}}
- | Component = {{GNF_GO|id=GO:0005768 |text = endosome}}
- | Process = {{GNF_GO|id=GO:0007264 |text = small GTPase mediated signal transduction}} {{GNF_GO|id=GO:0015031 |text = protein transport}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 23011
-    | Hs_Ensembl = ENSG00000080371
-    | Hs_RefseqProtein = NP_055814
-    | Hs_RefseqmRNA = NM_014999
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 12
-    | Hs_GenLoc_start = 70434925
-    | Hs_GenLoc_end = 70467417
-    | Hs_Uniprot = Q9UL25
-    | Mm_EntrezGene = 216344
-    | Mm_Ensembl = ENSMUSG00000020132
-    | Mm_RefseqmRNA = NM_024454
-    | Mm_RefseqProtein = NP_077774
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 10
-    | Mm_GenLoc_start = 114693972
-    | Mm_GenLoc_end = 114719701
-    | Mm_Uniprot = Q0PD35
-  }}
-}}
-'''RAB21, member RAS oncogene family''', also known as '''RAB21''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: RAB21 RAB21, member RAS oncogene family| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23011| accessdate = }}</ref>
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@@ Line 56: / Line 10: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Nagase T, Miyajima N, Tanaka A, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. |journal=DNA Res. |volume=2 |issue= 1 |pages= 37-43 |year= 1995 |pmid= 7788527 |doi=  }}
+*{{cite journal   |vauthors=Nagase T, Miyajima N, Tanaka A, etal |title=Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1 |journal=DNA Res. |volume=2 |issue= 1 |pages= 37–43 |year= 1995 |pmid= 7788527 |doi=10.1093/dnares/2.1.37  }}
-*{{cite journal  | author=Bao S, Zhu J, Garvey WT |title=Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects. |journal=Horm. Metab. Res. |volume=30 |issue= 11 |pages= 656-62 |year= 1999 |pmid= 9918381 |doi=  }}
+*{{cite journal  | vauthors=Bao S, Zhu J, Garvey WT |title=Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects |journal=Horm. Metab. Res. |volume=30 |issue= 11 |pages= 656–62 |year= 1999 |pmid= 9918381 |doi=10.1055/s-2007-978953  }}
-*{{cite journal  | author=Opdam FJ, Kamps G, Croes H, ''et al.'' |title=Expression of Rab small GTPases in epithelial Caco-2 cells: Rab21 is an apically located GTP-binding protein in polarised intestinal epithelial cells. |journal=Eur. J. Cell Biol. |volume=79 |issue= 5 |pages= 308-16 |year= 2000 |pmid= 10887961 |doi=  }}
+*{{cite journal  | vauthors=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=10.1101/gr.143000  | pmc=310948  }}
-*{{cite journal  | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788-95 |year= 2001 |pmid= 11076863 |doi=  }}
+*{{cite journal   |vauthors=Simpson JC, Wellenreuther R, Poustka A, etal |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287–92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058  | pmc=1083732 }}
-*{{cite journal  | author=Simpson JC, Wellenreuther R, Poustka A, ''et al.'' |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287-92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058 }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal  | author=Pereira-Leal JB, Seabra MC |title=Evolution of the Rab family of small GTP-binding proteins. |journal=J. Mol. Biol. |volume=313 |issue= 4 |pages= 889-901 |year= 2001 |pmid= 11697911 |doi= 10.1006/jmbi.2001.5072 }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal   |vauthors=Wiemann S, Arlt D, Huber W, etal |title=From ORFeome to biology: a functional genomics pipeline |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704  | pmc=528930 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Mehrle A, Rosenfelder H, Schupp I, etal |title=The LIFEdb database in 2006 |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139  | pmc=1347501 }}
-*{{cite journal  | author=Wiemann S, Arlt D, Huber W, ''et al.'' |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136-44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 }}
-*{{cite journal  | author=Mehrle A, Rosenfelder H, Schupp I, ''et al.'' |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415-8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 }}
-*{{cite journal  | author=Pellinen T, Arjonen A, Vuoriluoto K, ''et al.'' |title=Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins. |journal=J. Cell Biol. |volume=173 |issue= 5 |pages= 767-80 |year= 2006 |pmid= 16754960 |doi= 10.1083/jcb.200509019 }}
 }}
 {{refend}}
+{{PDB Gallery|geneid=23011}}
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+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
+| update_summary = yes
+| update_citations = yes
+}}
 {{gene-12-stub}}
-{{WikiDoc Sources}}

RAB21: Difference between revisions

Revision as of 08:45, 10 September 2017

References

Further reading

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