RAB34: Difference between revisions

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{{Infobox_gene}}
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'''Ras-related protein Rab-34''' is a [[protein]] that in humans is encoded by the ''RAB34'' [[gene]].<ref name="pmid12446704">{{cite journal | vauthors = Sun P, Yamamoto H, Suetsugu S, Miki H, Takenawa T, Endo T | title = Small GTPase Rah/Rab34 is associated with membrane ruffles and macropinosomes and promotes macropinosome formation | journal = J Biol Chem | volume = 278 | issue = 6 | pages = 4063–71 |date=Feb 2003 | pmid = 12446704 | pmc =  | doi = 10.1074/jbc.M208699200 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RAB34 RAB34, member RAS oncogene family| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=83871| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source = 
| PDB =
| Name = RAB34, member RAS oncogene family
| HGNCid = 16519
| Symbol = RAB34
| AltSymbols =; RAB39; RAH
| OMIM = 
| ECnumber = 
| Homologene = 12908
| MGIid = 104606
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0005525 |text = GTP binding}}
| Component = {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007264 |text = small GTPase mediated signal transduction}} {{GNF_GO|id=GO:0015031 |text = protein transport}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 83871
    | Hs_Ensembl = ENSG00000109113
    | Hs_RefseqProtein = NP_114140
    | Hs_RefseqmRNA = NM_031934
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 17
    | Hs_GenLoc_start = 24065430
    | Hs_GenLoc_end = 24069328
    | Hs_Uniprot = Q9BZG1
    | Mm_EntrezGene = 19376
    | Mm_Ensembl = ENSMUSG00000002059
    | Mm_RefseqmRNA = XM_984679
    | Mm_RefseqProtein = XP_989773
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 11
    | Mm_GenLoc_start = 78004635
    | Mm_GenLoc_end = 78008383
    | Mm_Uniprot = Q5SYL6
  }}
}}
'''RAB34, member RAS oncogene family''', also known as '''RAB34''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: RAB34 RAB34, member RAS oncogene family| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=83871| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
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| citations =  
| citations =  
*{{cite journal  | author=Sun P, Yamamoto H, Suetsugu S, ''et al.'' |title=Small GTPase Rah/Rab34 is associated with membrane ruffles and macropinosomes and promotes macropinosome formation. |journal=J. Biol. Chem. |volume=278 |issue= 6 |pages= 4063-71 |year= 2003 |pmid= 12446704 |doi= 10.1074/jbc.M208699200 }}
*{{cite journal  | vauthors=Wang T, Hong W |title=Interorganellar regulation of lysosome positioning by the Golgi apparatus through Rab34 interaction with Rab-interacting lysosomal protein. |journal=Mol. Biol. Cell |volume=13 |issue= 12 |pages= 4317–32 |year= 2003 |pmid= 12475955 |doi= 10.1091/mbc.E02-05-0280 | pmc=138636 }}
*{{cite journal  | author=Wang T, Hong W |title=Interorganellar regulation of lysosome positioning by the Golgi apparatus through Rab34 interaction with Rab-interacting lysosomal protein. |journal=Mol. Biol. Cell |volume=13 |issue= 12 |pages= 4317-32 |year= 2003 |pmid= 12475955 |doi= 10.1091/mbc.E02-05-0280 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Chen T, Han Y, Yang M, etal |title=Rab39, a novel Golgi-associated Rab GTPase from human dendritic cells involved in cellular endocytosis. |journal=Biochem. Biophys. Res. Commun. |volume=303 |issue= 4 |pages= 1114–20 |year= 2003 |pmid= 12684051 |doi=10.1016/S0006-291X(03)00482-0 }}
*{{cite journal | author=Chen T, Han Y, Yang M, ''et al.'' |title=Rab39, a novel Golgi-associated Rab GTPase from human dendritic cells involved in cellular endocytosis. |journal=Biochem. Biophys. Res. Commun. |volume=303 |issue= 4 |pages= 1114-20 |year= 2003 |pmid= 12684051 |doi=  }}
*{{cite journal  | vauthors=Wang T, Wong KK, Hong W |title=A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34. |journal=Mol. Biol. Cell |volume=15 |issue= 2 |pages= 815–26 |year= 2004 |pmid= 14668488 |doi= 10.1091/mbc.E03-06-0413 | pmc=329395 }}
*{{cite journal  | author=Wang T, Wong KK, Hong W |title=A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34. |journal=Mol. Biol. Cell |volume=15 |issue= 2 |pages= 815-26 |year= 2004 |pmid= 14668488 |doi= 10.1091/mbc.E03-06-0413 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Barrios-Rodiles M, Brown KR, Ozdamar B, etal |title=High-throughput mapping of a dynamic signaling network in mammalian cells. |journal=Science |volume=307 |issue= 5715 |pages= 1621–5 |year= 2005 |pmid= 15761153 |doi= 10.1126/science.1105776 }}
*{{cite journal | author=Barrios-Rodiles M, Brown KR, Ozdamar B, ''et al.'' |title=High-throughput mapping of a dynamic signaling network in mammalian cells. |journal=Science |volume=307 |issue= 5715 |pages= 1621-5 |year= 2005 |pmid= 15761153 |doi= 10.1126/science.1105776 }}
*{{cite journal  | vauthors=Colucci AM, Campana MC, Bellopede M, Bucci C |title=The Rab-interacting lysosomal protein, a Rab7 and Rab34 effector, is capable of self-interaction. |journal=Biochem. Biophys. Res. Commun. |volume=334 |issue= 1 |pages= 128–33 |year= 2005 |pmid= 15996637 |doi= 10.1016/j.bbrc.2005.06.067 }}
*{{cite journal  | author=Colucci AM, Campana MC, Bellopede M, Bucci C |title=The Rab-interacting lysosomal protein, a Rab7 and Rab34 effector, is capable of self-interaction. |journal=Biochem. Biophys. Res. Commun. |volume=334 |issue= 1 |pages= 128-33 |year= 2005 |pmid= 15996637 |doi= 10.1016/j.bbrc.2005.06.067 }}
*{{cite journal  | vauthors=Speight P, Silverman M |title=Diacylglycerol-activated Hmunc13 serves as an effector of the GTPase Rab34. |journal=Traffic |volume=6 |issue= 10 |pages= 858–65 |year= 2005 |pmid= 16138900 |doi= 10.1111/j.1600-0854.2005.00321.x }}
*{{cite journal  | author=Speight P, Silverman M |title=Diacylglycerol-activated Hmunc13 serves as an effector of the GTPase Rab34. |journal=Traffic |volume=6 |issue= 10 |pages= 858-65 |year= 2005 |pmid= 16138900 |doi= 10.1111/j.1600-0854.2005.00321.x }}
*{{cite journal   |vauthors=Otsuki T, Ota T, Nishikawa T, etal |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 }}
*{{cite journal | author=Otsuki T, Ota T, Nishikawa T, ''et al.'' |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117-26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 }}
*{{cite journal  | vauthors=Coyne CB, Shen L, Turner JR, Bergelson JM |title=Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5. |journal=Cell Host Microbe |volume=2 |issue= 3 |pages= 181–92 |year= 2007 |pmid= 18005733 |doi= 10.1016/j.chom.2007.07.003 | pmc=2719558 }}
*{{cite journal  | author=Coyne CB, Shen L, Turner JR, Bergelson JM |title=Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5. |journal=Cell Host Microbe |volume=2 |issue= 3 |pages= 181-92 |year= 2007 |pmid= 18005733 |doi= 10.1016/j.chom.2007.07.003 }}
}}
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Revision as of 08:46, 10 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Ras-related protein Rab-34 is a protein that in humans is encoded by the RAB34 gene.[1][2]


References

  1. Sun P, Yamamoto H, Suetsugu S, Miki H, Takenawa T, Endo T (Feb 2003). "Small GTPase Rah/Rab34 is associated with membrane ruffles and macropinosomes and promotes macropinosome formation". J Biol Chem. 278 (6): 4063–71. doi:10.1074/jbc.M208699200. PMID 12446704.
  2. "Entrez Gene: RAB34 RAB34, member RAS oncogene family".

Further reading