RNF123: Difference between revisions

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Latest revision as of 09:20, 10 September 2017

E3 ubiquitin-protein ligase RNF123 is an enzyme that in humans is encoded by the RNF123 gene.^[1]

The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions.^[1]

References

↑ ^1.0 ^1.1 "Entrez Gene: RNF123 ring finger protein 123".

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
Kamura T, Hara T, Matsumoto M, et al. (2005). "Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase". Nat. Cell Biol. 6 (12): 1229–35. doi:10.1038/ncb1194. PMID 15531880.
Kotoshiba S, Kamura T, Hara T, et al. (2005). "Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase". J. Biol. Chem. 280 (18): 17694–700. doi:10.1074/jbc.M500866200. PMID 15746103.
Hara T, Kamura T, Kotoshiba S, et al. (2005). "Role of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle". Mol. Cell. Biol. 25 (21): 9292–303. doi:10.1128/MCB.25.21.9292-9303.2005. PMC 1265808. PMID 16227581.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

External links

RNF123+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.

[entrez-1] 1.0 ^1.1 "Entrez Gene: RNF123 ring finger protein 123".

[1]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''E3 ubiquitin-protein ligase RNF123''' is an [[enzyme]] that in humans is encoded by the ''RNF123'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: RNF123 ring finger protein 123| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=63891| accessdate = }}</ref>
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Ring finger protein 123
- | HGNCid = 21148
- | Symbol = RNF123
- | AltSymbols =; DKFZp686C2222; FLJ12565; FP1477; KPC1; MGC163504
- | OMIM =
- | ECnumber =
- | Homologene = 11112
- | MGIid = 2148796
- | GeneAtlas_image1 = PBB_GE_RNF123_221063_x_at_tn.png
- | Function = {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0016874 |text = ligase activity}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
- | Component = {{GNF_GO|id=GO:0005737 |text = cytoplasm}}
- | Process = {{GNF_GO|id=GO:0006512 |text = ubiquitin cycle}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 63891
-    | Hs_Ensembl = ENSG00000164068
-    | Hs_RefseqProtein = NP_071347
-    | Hs_RefseqmRNA = NM_022064
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 3
-    | Hs_GenLoc_start = 49701974
-    | Hs_GenLoc_end = 49733961
-    | Hs_Uniprot = Q5XPI4
-    | Mm_EntrezGene = 84585
-    | Mm_Ensembl = ENSMUSG00000041528
-    | Mm_RefseqmRNA = NM_032543
-    | Mm_RefseqProtein = NP_115932
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 9
-    | Mm_GenLoc_start = 107909778
-    | Mm_GenLoc_end = 107937402
-    | Mm_Uniprot = Q05CH9
-  }}
-}}
-'''Ring finger protein 123''', also known as '''RNF123''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: RNF123 ring finger protein 123| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=63891| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
 {{PBB_Summary
 | section_title =
-| summary_text = The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions.<ref name="entrez">{{cite web | title = Entrez Gene: RNF123 ring finger protein 123| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=63891| accessdate = }}</ref>
+| summary_text = The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions.<ref name="entrez">{{cite web | title = Entrez Gene: RNF123 ring finger protein 123| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=63891| accessdate = }}</ref>
 }}
@@ Line 58: / Line 12: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
@@ Line 64: / Line 18: @@
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using ''in vitro'' site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788-95 |year= 2001 |pmid= 11076863 |doi=  }}
+*{{cite journal  | vauthors=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using ''in vitro'' site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=10.1101/gr.143000  | pmc=310948  }}
-*{{cite journal  | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422-35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
+*{{cite journal   |vauthors=Wiemann S, Weil B, Wellenreuther R, etal |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.GR1547R  | pmc=311072 }}
-*{{cite journal  | author=Simpson JC, Wellenreuther R, Poustka A, ''et al.'' |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287-92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058 }}
+*{{cite journal   |vauthors=Simpson JC, Wellenreuther R, Poustka A, etal |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287–92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058  | pmc=1083732 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
+*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
-*{{cite journal  | author=Colland F, Jacq X, Trouplin V, ''et al.'' |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324-32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 }}
+*{{cite journal   |vauthors=Colland F, Jacq X, Trouplin V, etal |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104  | pmc=442148 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=Wiemann S, Arlt D, Huber W, ''et al.'' |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136-44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 }}
+*{{cite journal   |vauthors=Wiemann S, Arlt D, Huber W, etal |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704  | pmc=528930 }}
-*{{cite journal  | author=Wan D, Gong Y, Qin W, ''et al.'' |title=Large-scale cDNA transfection screening for genes related to cancer development and progression. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 44 |pages= 15724-9 |year= 2004 |pmid= 15498874 |doi= 10.1073/pnas.0404089101 }}
+*{{cite journal   |vauthors=Wan D, Gong Y, Qin W, etal |title=Large-scale cDNA transfection screening for genes related to cancer development and progression. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 44 |pages= 15724–9 |year= 2004 |pmid= 15498874 |doi= 10.1073/pnas.0404089101  | pmc=524842 }}
-*{{cite journal  | author=Kamura T, Hara T, Matsumoto M, ''et al.'' |title=Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase. |journal=Nat. Cell Biol. |volume=6 |issue= 12 |pages= 1229-35 |year= 2005 |pmid= 15531880 |doi= 10.1038/ncb1194 }}
+*{{cite journal   |vauthors=Kamura T, Hara T, Matsumoto M, etal |title=Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase. |journal=Nat. Cell Biol. |volume=6 |issue= 12 |pages= 1229–35 |year= 2005 |pmid= 15531880 |doi= 10.1038/ncb1194 }}
-*{{cite journal  | author=Kotoshiba S, Kamura T, Hara T, ''et al.'' |title=Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase. |journal=J. Biol. Chem. |volume=280 |issue= 18 |pages= 17694-700 |year= 2005 |pmid= 15746103 |doi= 10.1074/jbc. M500866200 }}
+*{{cite journal   |vauthors=Kotoshiba S, Kamura T, Hara T, etal |title=Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase. |journal=J. Biol. Chem. |volume=280 |issue= 18 |pages= 17694–700 |year= 2005 |pmid= 15746103 |doi= 10.1074/jbc.M500866200 }}
-*{{cite journal  | author=Hara T, Kamura T, Kotoshiba S, ''et al.'' |title=Role of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle. |journal=Mol. Cell. Biol. |volume=25 |issue= 21 |pages= 9292-303 |year= 2005 |pmid= 16227581 |doi= 10.1128/MCB.25.21.9292-9303.2005 }}
+*{{cite journal   |vauthors=Hara T, Kamura T, Kotoshiba S, etal |title=Role of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle. |journal=Mol. Cell. Biol. |volume=25 |issue= 21 |pages= 9292–303 |year= 2005 |pmid= 16227581 |doi= 10.1128/MCB.25.21.9292-9303.2005  | pmc=1265808 }}
-*{{cite journal  | author=Mehrle A, Rosenfelder H, Schupp I, ''et al.'' |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415-8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 }}
+*{{cite journal   |vauthors=Mehrle A, Rosenfelder H, Schupp I, etal |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139  | pmc=1347501 }}
-*{{cite journal  | author=Ewing RM, Chu P, Elisma F, ''et al.'' |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue=  |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 }}
+*{{cite journal   |vauthors=Ewing RM, Chu P, Elisma F, etal |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue=  1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134  | pmc=1847948 }}
 }}
 {{refend}}
@@ Line 84: / Line 38: @@
 * {{MeshName|RNF123+protein,+human}}
-{{protein-stub}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
-{{WikiDoc Sources}}
+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
+| update_summary = yes
+| update_citations = yes
+}}
+[[Category:RING finger proteins]]
+{{gene-3-stub}}

RNF123: Difference between revisions

Latest revision as of 09:20, 10 September 2017

Contents

See also

References

Further reading

External links

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