RPP38: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''Ribonuclease P protein subunit p38''' is an [[enzyme]] that in humans is encoded by the ''RPP38'' [[gene]].<ref name="pmid9037013">{{cite journal | vauthors = Eder PS, Kekuda R, Stolc V, Altman S | title = Characterization of two scleroderma autoimmune antigens that copurify with human ribonuclease P | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 94 | issue = 4 | pages = 1101–6  | date = March 1997 | pmid = 9037013 | pmc = 19751 | doi = 10.1073/pnas.94.4.1101 }}</ref><ref name="pmid9630247">{{cite journal | vauthors = Jarrous N, Eder PS, Guerrier-Takada C, Hoog C, Altman S | title = Autoantigenic properties of some protein subunits of catalytically active complexes of human ribonuclease P | journal = RNA | volume = 4 | issue = 4 | pages = 407–17  | date = June 1998 | pmid = 9630247 | pmc = 1369627 | doi = }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RPP38 ribonuclease P/MRP 38kDa subunit| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10557| accessdate = }}</ref>
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Interactions ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =  
| Name = Ribonuclease P/MRP 38kDa subunit
| HGNCid = 30329
| Symbol = RPP38
| AltSymbols =; RP11-455B2.5
| OMIM = 606116
| ECnumber = 
| Homologene = 4680
| MGIid = 2443607
| GeneAtlas_image1 = PBB_GE_RPP38_205562_at_tn.png
| Function = {{GNF_GO|id=GO:0004526 |text = ribonuclease P activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0016787 |text = hydrolase activity}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005655 |text = nucleolar ribonuclease P complex}}
| Process = {{GNF_GO|id=GO:0008033 |text = tRNA processing}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 10557
    | Hs_Ensembl = ENSG00000152464
    | Hs_RefseqProtein = NP_006405
    | Hs_RefseqmRNA = NM_006414
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 10
    | Hs_GenLoc_start = 15179185
    | Hs_GenLoc_end = 15188135
    | Hs_Uniprot = P78345
    | Mm_EntrezGene = 227522
    | Mm_Ensembl = ENSMUSG00000049950
    | Mm_RefseqmRNA = NM_001013376
    | Mm_RefseqProtein = NP_001013394
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 2
    | Mm_GenLoc_start = 3246221
    | Mm_GenLoc_end = 3249874
    | Mm_Uniprot = Q8BX36
  }}
}}
'''Ribonuclease P/MRP 38kDa subunit''', also known as '''RPP38''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: RPP38 ribonuclease P/MRP 38kDa subunit| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10557| accessdate = }}</ref>


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RPP38 has been shown to [[Protein-protein interaction|interact]] with [[POP4 (gene)|POP4]].<ref name=pmid15096576>{{cite journal | vauthors = Welting TJ, van Venrooij WJ, Pruijn GJ | title = Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex | journal = Nucleic Acids Res. | volume = 32 | issue = 7 | pages = 2138–46 | year = 2004 | pmid = 15096576 | pmc = 407822 | doi = 10.1093/nar/gkh539 }}</ref>
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| summary_text =  
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==References==
== References ==
{{reflist|2}}
{{reflist}}
==Further reading==
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1-2 | pages = 171–4 | year = 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
| citations =
* {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1-2 | pages = 149–56 | year = 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
*{{cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi= }}
* {{cite journal | vauthors = Jarrous N, Wolenski JS, Wesolowski D, Lee C, Altman S | title = Localization in the nucleolus and coiled bodies of protein subunits of the ribonucleoprotein ribonuclease P | journal = J. Cell Biol. | volume = 146 | issue = 3 | pages = 559–72 | year = 1999 | pmid = 10444065 | pmc = 2150555 | doi = 10.1083/jcb.146.3.559 }}
*{{cite journal  | author=Eder PS, Kekuda R, Stolc V, Altman S |title=Characterization of two scleroderma autoimmune antigens that copurify with human ribonuclease P. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 4 |pages= 1101-6 |year= 1997 |pmid= 9037013 |doi=  }}
* {{cite journal | vauthors = Jiang T, Guerrier-Takada C, Altman S | title = Protein-RNA interactions in the subunits of human nuclear RNase P | journal = RNA | volume = 7 | issue = 7 | pages = 937–41 | year = 2001 | pmid = 11455963 | pmc = 1370153 | doi = 10.1017/S1355838201010299 }}
*{{cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi= }}
* {{cite journal | vauthors = Welting TJ, van Venrooij WJ, Pruijn GJ | title = Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex | journal = Nucleic Acids Res. | volume = 32 | issue = 7 | pages = 2138–46 | year = 2004 | pmid = 15096576 | pmc = 407822 | doi = 10.1093/nar/gkh539 }}
*{{cite journal  | author=Jarrous N, Eder PS, Guerrier-Takada C, ''et al.'' |title=Autoantigenic properties of some protein subunits of catalytically active complexes of human ribonuclease P. |journal=RNA |volume=4 |issue= 4 |pages= 407-17 |year= 1998 |pmid= 9630247 |doi=  }}
* {{cite journal | vauthors = Suzuki Y, Yamashita R, Shirota M, Sakakibara Y, Chiba J, Mizushima-Sugano J, Nakai K, Sugano S | title = Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions | journal = Genome Res. | volume = 14 | issue = 9 | pages = 1711–8 | year = 2004 | pmid = 15342556 | pmc = 515316 | doi = 10.1101/gr.2435604 }}
*{{cite journal | author=Jarrous N, Wolenski JS, Wesolowski D, ''et al.'' |title=Localization in the nucleolus and coiled bodies of protein subunits of the ribonucleoprotein ribonuclease P. |journal=J. Cell Biol. |volume=146 |issue= 3 |pages= 559-72 |year= 1999 |pmid= 10444065 |doi= }}
* {{cite journal | vauthors = Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M | title = Nucleolar proteome dynamics | journal = Nature | volume = 433 | issue = 7021 | pages = 77–83 | year = 2005 | pmid = 15635413 | doi = 10.1038/nature03207 }}
*{{cite journal | author=Jiang T, Guerrier-Takada C, Altman S |title=Protein-RNA interactions in the subunits of human nuclear RNase P. |journal=RNA |volume=7 |issue= 7 |pages= 937-41 |year= 2001 |pmid= 11455963 |doi=  }}
* {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | year = 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Welting TJ, van Venrooij WJ, Pruijn GJ |title=Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex. |journal=Nucleic Acids Res. |volume=32 |issue= 7 |pages= 2138-46 |year= 2004 |pmid= 15096576 |doi= 10.1093/nar/gkh539 }}
*{{cite journal | author=Deloukas P, Earthrowl ME, Grafham DV, ''et al.'' |title=The DNA sequence and comparative analysis of human chromosome 10. |journal=Nature |volume=429 |issue= 6990 |pages= 375-81 |year= 2004 |pmid= 15164054 |doi= 10.1038/nature02462 }}
*{{cite journal  | author=Suzuki Y, Yamashita R, Shirota M, ''et al.'' |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711-8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal | author=Andersen JS, Lam YW, Leung AK, ''et al.'' |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77-83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
}}
{{refend}}
{{refend}}


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Latest revision as of 09:27, 10 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Ribonuclease P protein subunit p38 is an enzyme that in humans is encoded by the RPP38 gene.[1][2][3]

Interactions

RPP38 has been shown to interact with POP4.[4]

References

  1. ↑ Eder PS, Kekuda R, Stolc V, Altman S (March 1997). "Characterization of two scleroderma autoimmune antigens that copurify with human ribonuclease P". Proc. Natl. Acad. Sci. U.S.A. 94 (4): 1101–6. doi:10.1073/pnas.94.4.1101. PMC 19751. PMID 9037013.
  2. ↑ Jarrous N, Eder PS, Guerrier-Takada C, Hoog C, Altman S (June 1998). "Autoantigenic properties of some protein subunits of catalytically active complexes of human ribonuclease P". RNA. 4 (4): 407–17. PMC 1369627. PMID 9630247.
  3. ↑ "Entrez Gene: RPP38 ribonuclease P/MRP 38kDa subunit".
  4. ↑ Welting TJ, van Venrooij WJ, Pruijn GJ (2004). "Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex". Nucleic Acids Res. 32 (7): 2138–46. doi:10.1093/nar/gkh539. PMC 407822. PMID 15096576.

Further reading


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