SFRS4: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
m (Robot: Automated text replacement (-{{reflist}} +{{reflist|2}}, -<references /> +{{reflist|2}}, -{{WikiDoc Cardiology Network Infobox}} +))
 
m (Bot: HTTP→HTTPS)
Line 1: Line 1:
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Splicing factor, arginine/serine-rich 4''' is a [[protein]] that in humans is encoded by the ''SFRS4'' [[gene]].<ref name="pmid8321209">{{cite journal |author1=Zahler AM |author2=Neugebauer KM |author3=Stolk JA |author4=Roth MB | title = Human SR proteins and isolation of a cDNA encoding SRp75 | journal = Mol Cell Biol | volume = 13 | issue = 7 | pages = 4023–8 |date=Jul 1993 | pmid = 8321209 | pmc = 359951 | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SFRS4 splicing factor, arginine/serine-rich 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6429| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
 
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Splicing factor, arginine/serine-rich 4
| HGNCid = 10786
| Symbol = SFRS4
| AltSymbols =; SRP75
| OMIM = 601940
| ECnumber = 
| Homologene = 25624
| MGIid = 
| GeneAtlas_image1 = PBB_GE_SFRS4_201696_at_tn.png
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0031202 |text = RNA splicing factor activity, transesterification mechanism}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006397 |text = mRNA processing}} {{GNF_GO|id=GO:0008380 |text = RNA splicing}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 6429
    | Hs_Ensembl = ENSG00000116350
    | Hs_RefseqProtein = NP_005617
    | Hs_RefseqmRNA = NM_005626
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 29346842
    | Hs_GenLoc_end = 29381086
    | Hs_Uniprot = Q08170
    | Mm_EntrezGene = 
    | Mm_Ensembl = 
    | Mm_RefseqmRNA = 
    | Mm_RefseqProtein = 
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 
    | Mm_GenLoc_start = 
    | Mm_GenLoc_end = 
    | Mm_Uniprot = 
  }}
}}
'''Splicing factor, arginine/serine-rich 4''', also known as '''SFRS4''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SFRS4 splicing factor, arginine/serine-rich 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6429| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
Line 53: Line 7:
| summary_text =  
| summary_text =  
}}
}}
==Interactions==
SFRS4 has been shown to [[Protein-protein interaction|interact]] with [[Pinin]].<ref name=pmid14578391>{{cite journal |last=Zimowska |first=Grazyna |authorlink= |author2=Shi Jia |author3=Munguba Gustavo |author4=Jackson Moira R |author5=Alpatov Roman |author6=Simmons Matthew N |author7=Shi Yujiang |author8=Sugrue Stephen P  |date=Nov 2003 |title=Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells |journal=Invest. Ophthalmol. Vis. Sci. |volume=44 |issue=11 |pages=4715–23 |publisher= |location = United States| issn = 0146-0404| pmid = 14578391 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1167/iovs.03-0240 }}</ref>


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Zahler AM, Lane WS, Stolk JA, Roth MB |title=SR proteins: a conserved family of pre-mRNA splicing factors. |journal=Genes Dev. |volume=6 |issue= 5 |pages= 837-47 |year= 1992 |pmid= 1577277 |doi=  }}
*{{cite journal  |author1=Zahler AM |author2=Lane WS |author3=Stolk JA |author4=Roth MB |title=SR proteins: a conserved family of pre-mRNA splicing factors |journal=Genes Dev. |volume=6 |issue= 5 |pages= 837–47 |year= 1992 |pmid= 1577277 |doi=10.1101/gad.6.5.837 }}
*{{cite journal | author=Ramchatesingh J, Zahler AM, Neugebauer KM, ''et al.'' |title=A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer. |journal=Mol. Cell. Biol. |volume=15 |issue= 9 |pages= 4898-907 |year= 1995 |pmid= 7651409 |doi=  }}
*{{cite journal   |vauthors=Ramchatesingh J, Zahler AM, Neugebauer KM, etal |title=A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer |journal=Mol. Cell. Biol. |volume=15 |issue= 9 |pages= 4898–907 |year= 1995 |pmid= 7651409 |doi= | pmc=230736 }}
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi= }}
*{{cite journal  |author1=Maruyama K |author2=Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
*{{cite journal  | author=Gui JF, Lane WS, Fu XD |title=A serine kinase regulates intracellular localization of splicing factors in the cell cycle. |journal=Nature |volume=369 |issue= 6482 |pages= 678-82 |year= 1994 |pmid= 8208298 |doi= 10.1038/369678a0 }}
*{{cite journal  |author1=Gui JF |author2=Lane WS |author3=Fu XD |title=A serine kinase regulates intracellular localization of splicing factors in the cell cycle |journal=Nature |volume=369 |issue= 6482 |pages= 678–82 |year= 1994 |pmid= 8208298 |doi= 10.1038/369678a0 }}
*{{cite journal | author=Zahler AM, Neugebauer KM, Stolk JA, Roth MB |title=Human SR proteins and isolation of a cDNA encoding SRp75. |journal=Mol. Cell. Biol. |volume=13 |issue= 7 |pages= 4023-8 |year= 1993 |pmid= 8321209 |doi=  }}
*{{cite journal   |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 }}
*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
*{{cite journal  |author1=Zhang WJ |author2=Wu JY |title=Sip1, a Novel RS Domain-Containing Protein Essential for Pre-mRNA Splicing |journal=Mol. Cell. Biol. |volume=18 |issue= 2 |pages= 676–84 |year= 1998 |pmid= 9447963 |doi= | pmc=108778 }}
*{{cite journal  | author=Zhang WJ, Wu JY |title=Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing. |journal=Mol. Cell. Biol. |volume=18 |issue= 2 |pages= 676-84 |year= 1998 |pmid= 9447963 |doi=  }}
*{{cite journal  |author1=Blencowe BJ |author2=Issner R |author3=Nickerson JA |author4=Sharp PA |title=A coactivator of pre-mRNA splicing |journal=Genes Dev. |volume=12 |issue= 7 |pages= 996–1009 |year= 1998 |pmid= 9531537 |doi=10.1101/gad.12.7.996  | pmc=316672 }}
*{{cite journal | author=Blencowe BJ, Issner R, Nickerson JA, Sharp PA |title=A coactivator of pre-mRNA splicing. |journal=Genes Dev. |volume=12 |issue= 7 |pages= 996-1009 |year= 1998 |pmid= 9531537 |doi=  }}
*{{cite journal   |vauthors=Papoutsopoulou S, Nikolakaki E, Chalepakis G, etal |title=SR protein-specific kinase 1 is highly expressed in testis and phosphorylates protamine 1 |journal=Nucleic Acids Res. |volume=27 |issue= 14 |pages= 2972–80 |year= 1999 |pmid= 10390541 |doi=10.1093/nar/27.14.2972  | pmc=148514 }}
*{{cite journal | author=Papoutsopoulou S, Nikolakaki E, Chalepakis G, ''et al.'' |title=SR protein-specific kinase 1 is highly expressed in testis and phosphorylates protamine 1. |journal=Nucleic Acids Res. |volume=27 |issue= 14 |pages= 2972-80 |year= 1999 |pmid= 10390541 |doi=  }}
*{{cite journal   |vauthors=Monsalve M, Wu Z, Adelmant G, etal |title=Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1 |journal=Mol. Cell |volume=6 |issue= 2 |pages= 307–16 |year= 2000 |pmid= 10983978 |doi=10.1016/S1097-2765(00)00031-9 }}
*{{cite journal | author=Monsalve M, Wu Z, Adelmant G, ''et al.'' |title=Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. |journal=Mol. Cell |volume=6 |issue= 2 |pages= 307-16 |year= 2000 |pmid= 10983978 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Meissner M, Lopato S, Gotzmann J, etal |title=Proto-oncoprotein TLS/FUS is associated to the nuclear matrix and complexed with splicing factors PTB, SRm160, and SR proteins |journal=Exp. Cell Res. |volume=283 |issue= 2 |pages= 184–95 |year= 2003 |pmid= 12581738 |doi=10.1016/S0014-4827(02)00046-0  }}
*{{cite journal | author=Meissner M, Lopato S, Gotzmann J, ''et al.'' |title=Proto-oncoprotein TLS/FUS is associated to the nuclear matrix and complexed with splicing factors PTB, SRm160, and SR proteins. |journal=Exp. Cell Res. |volume=283 |issue= 2 |pages= 184-95 |year= 2003 |pmid= 12581738 |doi=  }}
*{{cite journal   |vauthors=Li J, Hawkins IC, Harvey CD, etal |title=Regulation of Alternative Splicing by SRrp86 and Its Interacting Proteins |journal=Mol. Cell. Biol. |volume=23 |issue= 21 |pages= 7437–47 |year= 2003 |pmid= 14559993 |doi=10.1128/MCB.23.21.7437-7447.2003  | pmc=207616 }}
*{{cite journal | author=Li J, Hawkins IC, Harvey CD, ''et al.'' |title=Regulation of alternative splicing by SRrp86 and its interacting proteins. |journal=Mol. Cell. Biol. |volume=23 |issue= 21 |pages= 7437-47 |year= 2003 |pmid= 14559993 |doi=  }}
*{{cite journal   |vauthors=Zimowska G, Shi J, Munguba G, etal |title=Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells |journal=Invest. Ophthalmol. Vis. Sci. |volume=44 |issue= 11 |pages= 4715–23 |year= 2003 |pmid= 14578391 |doi=10.1167/iovs.03-0240 }}
*{{cite journal | author=Zimowska G, Shi J, Munguba G, ''et al.'' |title=Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells. |journal=Invest. Ophthalmol. Vis. Sci. |volume=44 |issue= 11 |pages= 4715-23 |year= 2003 |pmid= 14578391 |doi= }}
*{{cite journal   |vauthors=de Graaf K, Hekerman P, Spelten O, etal |title=Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors |journal=J. Biol. Chem. |volume=279 |issue= 6 |pages= 4612–24 |year= 2004 |pmid= 14623875 |doi= 10.1074/jbc.M310794200 }}
*{{cite journal | author=de Graaf K, Hekerman P, Spelten O, ''et al.'' |title=Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors. |journal=J. Biol. Chem. |volume=279 |issue= 6 |pages= 4612-24 |year= 2004 |pmid= 14623875 |doi= 10.1074/jbc.M310794200 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Rush J, Moritz A, Lee KA, etal |title=Immunoaffinity profiling of tyrosine phosphorylation in cancer cells |journal=Nat. Biotechnol. |volume=23 |issue= 1 |pages= 94–101 |year= 2005 |pmid= 15592455 |doi= 10.1038/nbt1046 }}
*{{cite journal | author=Rush J, Moritz A, Lee KA, ''et al.'' |title=Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. |journal=Nat. Biotechnol. |volume=23 |issue= 1 |pages= 94-101 |year= 2005 |pmid= 15592455 |doi= 10.1038/nbt1046 }}
*{{cite journal   |vauthors=Barrios-Rodiles M, Brown KR, Ozdamar B, etal |title=High-throughput mapping of a dynamic signaling network in mammalian cells |journal=Science |volume=307 |issue= 5715 |pages= 1621–5 |year= 2005 |pmid= 15761153 |doi= 10.1126/science.1105776 }}
*{{cite journal | author=Barrios-Rodiles M, Brown KR, Ozdamar B, ''et al.'' |title=High-throughput mapping of a dynamic signaling network in mammalian cells. |journal=Science |volume=307 |issue= 5715 |pages= 1621-5 |year= 2005 |pmid= 15761153 |doi= 10.1126/science.1105776 }}
*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal   |vauthors=Gregory SG, Barlow KF, McLay KE, etal |title=The DNA sequence and biological annotation of human chromosome 1 |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
*{{cite journal | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
}}
}}
{{refend}}
{{refend}}


{{protein-stub}}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{WikiDoc Sources}}
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
 
 
{{gene-1-stub}}

Revision as of 06:13, 11 September 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Splicing factor, arginine/serine-rich 4 is a protein that in humans is encoded by the SFRS4 gene.[1][2]


Interactions

SFRS4 has been shown to interact with Pinin.[3]

References

  1. ↑ Zahler AM; Neugebauer KM; Stolk JA; Roth MB (Jul 1993). "Human SR proteins and isolation of a cDNA encoding SRp75". Mol Cell Biol. 13 (7): 4023–8. PMC 359951. PMID 8321209.
  2. ↑ "Entrez Gene: SFRS4 splicing factor, arginine/serine-rich 4".
  3. ↑ Zimowska, Grazyna; Shi Jia; Munguba Gustavo; Jackson Moira R; Alpatov Roman; Simmons Matthew N; Shi Yujiang; Sugrue Stephen P (Nov 2003). "Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells". Invest. Ophthalmol. Vis. Sci. United States. 44 (11): 4715–23. doi:10.1167/iovs.03-0240. ISSN 0146-0404. PMID 14578391.

Further reading



Retrieved from "https://www.wikidoc.org/index.php?title=SFRS4&oldid=1411056"