UIMC1: Difference between revisions

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'''BRCA1-A complex subunit RAP80''' is a [[protein]] that in humans is encoded by the ''UIMC1'' [[gene]].<ref name="pmid12080054">{{cite journal | vauthors = Yan Z, Kim YS, Jetten AM | title = RAP80, a novel nuclear protein that interacts with the retinoid-related testis-associated receptor | journal = J Biol Chem | volume = 277 | issue = 35 | pages = 32379–88 |date=Aug 2002 | pmid = 12080054 | pmc =  | doi = 10.1074/jbc.M203475200 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: UIMC1 ubiquitin interaction motif containing 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51720| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source = 
| PDB =
| Name = Ubiquitin interaction motif containing 1
| HGNCid = 30298
| Symbol = UIMC1
| AltSymbols =; RAP80; X2HRIP110
| OMIM = 609433
| ECnumber = 
| Homologene = 9455
| MGIid = 103185
| GeneAtlas_image1 = PBB_GE_UIMC1_220746_s_at_tn.png
| Function = {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0016481 |text = negative regulation of transcription}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 51720
    | Hs_Ensembl = ENSG00000087206
    | Hs_RefseqProtein = NP_057374
    | Hs_RefseqmRNA = NM_016290
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 5
    | Hs_GenLoc_start = 176264658
    | Hs_GenLoc_end = 176434665
    | Hs_Uniprot = Q96RL1
    | Mm_EntrezGene = 20184
    | Mm_Ensembl = ENSMUSG00000025878
    | Mm_RefseqmRNA = NM_011307
    | Mm_RefseqProtein = NP_035437
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 13
    | Mm_GenLoc_start = 55037502
    | Mm_GenLoc_end = 55109917
    | Mm_Uniprot = Q5RKX2
  }}
}}
'''Ubiquitin interaction motif containing 1''', also known as '''UIMC1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: UIMC1 ubiquitin interaction motif containing 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51720| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading
| citations =  
| citations =
*{{cite journal | author=Yan Z, Kim YS, Jetten AM |title=RAP80, a novel nuclear protein that interacts with the retinoid-related testis-associated receptor. |journal=J. Biol. Chem. |volume=277 |issue= 35 |pages= 32379-88 |year= 2002 |pmid= 12080054 |doi= 10.1074/jbc.M203475200 }}
* {{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
* {{cite journal   |vauthors=Kim YS, Nakanishi G, Oudes AJ, etal |title=Tsp57: a novel gene induced during a specific stage of spermatogenesis. |journal=Biol. Reprod. |volume=70 |issue= 1 |pages= 106–13 |year= 2004 |pmid= 12954732 |doi= 10.1095/biolreprod.103.018465 }}
*{{cite journal | author=Kim YS, Nakanishi G, Oudes AJ, ''et al.'' |title=Tsp57: a novel gene induced during a specific stage of spermatogenesis. |journal=Biol. Reprod. |volume=70 |issue= 1 |pages= 106-13 |year= 2004 |pmid= 12954732 |doi= 10.1095/biolreprod.103.018465 }}
* {{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
* {{cite journal   |vauthors=Colland F, Jacq X, Trouplin V, etal |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 | pmc=442148 }}
*{{cite journal | author=Colland F, Jacq X, Trouplin V, ''et al.'' |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324-32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 }}
* {{cite journal   |vauthors=Beausoleil SA, Jedrychowski M, Schwartz D, etal |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 | pmc=514446 }}
*{{cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, ''et al.'' |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130-5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 }}
* {{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
* {{cite journal   |vauthors=Olsen JV, Blagoev B, Gnad F, etal |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
* {{cite journal   |vauthors=Wang B, Matsuoka S, Ballif BA, etal |title=Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response. |journal=Science |volume=316 |issue= 5828 |pages= 1194–8 |year= 2007 |pmid= 17525340 |doi= 10.1126/science.1139476 |pmc=3573690}}
*{{cite journal | author=Wang B, Matsuoka S, Ballif BA, ''et al.'' |title=Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response. |journal=Science |volume=316 |issue= 5828 |pages= 1194-8 |year= 2007 |pmid= 17525340 |doi= 10.1126/science.1139476 }}
* {{cite journal   |vauthors=Sobhian B, Shao G, Lilli DR, etal |title=RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites. |journal=Science |volume=316 |issue= 5828 |pages= 1198–202 |year= 2007 |pmid= 17525341 |doi= 10.1126/science.1139516 | pmc=2706583 }}
*{{cite journal | author=Sobhian B, Shao G, Lilli DR, ''et al.'' |title=RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites. |journal=Science |volume=316 |issue= 5828 |pages= 1198-202 |year= 2007 |pmid= 17525341 |doi= 10.1126/science.1139516 }}
* {{cite journal  | vauthors=Kim H, Chen J, Yu X |title=Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response. |journal=Science |volume=316 |issue= 5828 |pages= 1202–5 |year= 2007 |pmid= 17525342 |doi= 10.1126/science.1139621 }}
*{{cite journal  | author=Kim H, Chen J, Yu X |title=Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response. |journal=Science |volume=316 |issue= 5828 |pages= 1202-5 |year= 2007 |pmid= 17525342 |doi= 10.1126/science.1139621 }}
* {{cite journal   |vauthors=Shebzukhov YV, Koroleva EP, Khlgatian SV, etal |title=RAP80/UIMC1 as cancer-associated antigen: alternative splice variants and their immunogenicity. |journal=Cancer Lett. |volume=255 |issue= 2 |pages= 255–62 |year= 2007 |pmid= 17562356 |doi= 10.1016/j.canlet.2007.04.013 }}
*{{cite journal | author=Shebzukhov YV, Koroleva EP, Khlgatian SV, ''et al.'' |title=RAP80/UIMC1 as cancer-associated antigen: alternative splice variants and their immunogenicity. |journal=Cancer Lett. |volume=255 |issue= 2 |pages= 255-62 |year= 2007 |pmid= 17562356 |doi= 10.1016/j.canlet.2007.04.013 }}
* {{cite journal   |vauthors=Yan J, Kim YS, Yang XP, etal |title=The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response. |journal=Cancer Res. |volume=67 |issue= 14 |pages= 6647–56 |year= 2007 |pmid= 17621610 |doi= 10.1158/0008-5472.CAN-07-0924 | pmc=2391092 }}
*{{cite journal | author=Yan J, Kim YS, Yang XP, ''et al.'' |title=The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response. |journal=Cancer Res. |volume=67 |issue= 14 |pages= 6647-56 |year= 2007 |pmid= 17621610 |doi= 10.1158/0008-5472.CAN-07-0924 }}
* {{cite journal   |vauthors=Yan J, Yang XP, Kim YS, etal |title=RAP80 interacts with the SUMO-conjugating enzyme UBC9 and is a novel target for sumoylation. |journal=Biochem. Biophys. Res. Commun. |volume=362 |issue= 1 |pages= 132–8 |year= 2007 |pmid= 17698038 |doi= 10.1016/j.bbrc.2007.07.158 | pmc=2049087 }}
*{{cite journal | author=Yan J, Yang XP, Kim YS, ''et al.'' |title=RAP80 interacts with the SUMO-conjugating enzyme UBC9 and is a novel target for sumoylation. |journal=Biochem. Biophys. Res. Commun. |volume=362 |issue= 1 |pages= 132-8 |year= 2007 |pmid= 17698038 |doi= 10.1016/j.bbrc.2007.07.158 }}
}}
}}
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Revision as of 09:44, 17 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

BRCA1-A complex subunit RAP80 is a protein that in humans is encoded by the UIMC1 gene.[1][2]


References

  1. ↑ Yan Z, Kim YS, Jetten AM (Aug 2002). "RAP80, a novel nuclear protein that interacts with the retinoid-related testis-associated receptor". J Biol Chem. 277 (35): 32379–88. doi:10.1074/jbc.M203475200. PMID 12080054.
  2. ↑ "Entrez Gene: UIMC1 ubiquitin interaction motif containing 1".

Further reading



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