XAF1: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
m (Robot: Automated text replacement (-{{reflist}} +{{reflist|2}}, -<references /> +{{reflist|2}}, -{{WikiDoc Cardiology Network Infobox}} +))
 
m (Bot: HTTP→HTTPS (v475))
 
Line 1: Line 1:
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''XIAP-associated factor 1''' is a [[protein]] that in humans is encoded by the ''XAF1'' [[gene]].<ref name="pmid12029096">{{cite journal | vauthors = Leaman DW, Chawla-Sarkar M, Vyas K, Reheman M, Tamai K, Toji S, Borden EC | title = Identification of X-linked inhibitor of apoptosis-associated factor-1 as an interferon-stimulated gene that augments TRAIL Apo2L-induced apoptosis | journal = J. Biol. Chem. | volume = 277 | issue = 32 | pages = 28504–11  | date = Aug 2002 | pmid = 12029096 | pmc =  | doi = 10.1074/jbc.M204851200 }}</ref><ref name="pmid11175744">{{cite journal | vauthors = Liston P, Fong WG, Kelly NL, Toji S, Miyazaki T, Conte D, Tamai K, Craig CG, McBurney MW, Korneluk RG | title = Identification of XAF1 as an antagonist of XIAP anti-Caspase activity | journal = Nat. Cell Biol. | volume = 3 | issue = 2 | pages = 128–33  | date = Feb 2001 | pmid = 11175744 | pmc = | doi = 10.1038/35055027 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: XAF1 XIAP associated factor-1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54739| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = XIAP associated factor-1
| HGNCid = 
| Symbol = XAF1
| AltSymbols =; BIRC4BP; HSXIAPAF1
| OMIM = 606717
| ECnumber = 
| Homologene = 49488
| MGIid = 3505735
| GeneAtlas_image1 = PBB_GE_XAF1_206133_at_tn.png
| Function = {{GNF_GO|id=GO:0008270 |text = zinc ion binding}}
| Component =
| Process =
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 54739
    | Hs_Ensembl = ENSG00000132530
    | Hs_RefseqProtein = NP_059993
    | Hs_RefseqmRNA = NM_017523
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 17
    | Hs_GenLoc_start = 6599518
    | Hs_GenLoc_end = 6619685
    | Hs_Uniprot = 
    | Mm_EntrezGene = 327959
    | Mm_Ensembl = ENSMUSG00000040483
    | Mm_RefseqmRNA = NM_001037713
    | Mm_RefseqProtein = NP_001032802
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 11
    | Mm_GenLoc_start = 72117858
    | Mm_GenLoc_end = 72125254
    | Mm_Uniprot = 
  }}
}}
'''XIAP associated factor-1''', also known as '''XAF1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: XAF1 XIAP associated factor-1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54739| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
X-linked inhibitor of apoptosis (XIAP; MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases (e.g., CASP3; MIM 600636). XIAP has 3 BIR domains and a C-terminal RING zinc finger that possesses E3 ubiquitin ligase (see MIM 601623) activity. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells (Liston et al., 2001).[supplied by OMIM]<ref name="entrez" />
{{PBB_Summary
| section_title =
| summary_text = X-linked inhibitor of apoptosis (XIAP; MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases (e.g., CASP3; MIM 600636). XIAP has 3 BIR domains and a C-terminal RING zinc finger that possesses E3 ubiquitin ligase (see MIM 601623) activity. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells (Liston et al., 2001).[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: XAF1 XIAP associated factor-1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54739| accessdate = }}</ref>
}}


==References==
== Interactions ==
{{reflist|2}}
 
==Further reading==
XAF1 has been shown to [[Protein-protein interaction|interact]] with [[XIAP]].<ref name=pmid11175744 />
 
== References ==
{{reflist}}
{{Clear}}
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Fong WG, Liston P, Rajcan-Separovic E, St Jean M, Craig C, Korneluk RG | title = Expression and genetic analysis of XIAP-associated factor 1 (XAF1) in cancer cell lines | journal = Genomics | volume = 70 | issue = 1 | pages = 113–22 | year = 2000 | pmid = 11087668 | doi = 10.1006/geno.2000.6364 }}
| citations =
* {{cite journal | vauthors = Wistow G, Bernstein SL, Wyatt MK, Ray S, Behal A, Touchman JW, Bouffard G, Smith D, Peterson K | title = Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts | journal = Mol. Vis. | volume = 8 | issue = | pages = 196–204 | year = 2002 | pmid = 12107411 | doi = }}
*{{cite journal | author=Fong WG, Liston P, Rajcan-Separovic E, ''et al.'' |title=Expression and genetic analysis of XIAP-associated factor 1 (XAF1) in cancer cell lines. |journal=Genomics |volume=70 |issue= 1 |pages= 113-22 |year= 2001 |pmid= 11087668 |doi= 10.1006/geno.2000.6364 }}
* {{cite journal | vauthors = Byun DS, Cho K, Ryu BK, Lee MG, Kang MJ, Kim HR, Chi SG | title = Hypermethylation of XIAP-associated factor 1, a putative tumor suppressor gene from the 17p13.2 locus, in human gastric adenocarcinomas | journal = Cancer Res. | volume = 63 | issue = 21 | pages = 7068–75 | year = 2003 | pmid = 14612497 | doi = }}
*{{cite journal | author=Liston P, Fong WG, Kelly NL, ''et al.'' |title=Identification of XAF1 as an antagonist of XIAP anti-Caspase activity. |journal=Nat. Cell Biol. |volume=3 |issue= 2 |pages= 128-33 |year= 2001 |pmid= 11175744 |doi= 10.1038/35055027 }}
* {{cite journal | vauthors = Ng KC, Campos EI, Martinka M, Li G | title = XAF1 expression is significantly reduced in human melanoma | journal = J. Invest. Dermatol. | volume = 123 | issue = 6 | pages = 1127–34 | year = 2004 | pmid = 15610524 | doi = 10.1111/j.0022-202X.2004.23467.x }}
*{{cite journal | author=Leaman DW, Chawla-Sarkar M, Vyas K, ''et al.'' |title=Identification of X-linked inhibitor of apoptosis-associated factor-1 as an interferon-stimulated gene that augments TRAIL Apo2L-induced apoptosis. |journal=J. Biol. Chem. |volume=277 |issue= 32 |pages= 28504-11 |year= 2002 |pmid= 12029096 |doi= 10.1074/jbc.M204851200 }}
* {{cite journal | vauthors = Wang J, He H, Yu L, Xia HH, Lin MC, Gu Q, Li M, Zou B, An X, Jiang B, Kung HF, Wong BC | title = HSF1 down-regulates XAF1 through transcriptional regulation | journal = J. Biol. Chem. | volume = 281 | issue = 5 | pages = 2451–9 | year = 2006 | pmid = 16303760 | doi = 10.1074/jbc.M505890200 }}
*{{cite journal | author=Wistow G, Bernstein SL, Wyatt MK, ''et al.'' |title=Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts. |journal=Mol. Vis. |volume=8 |issue= |pages= 196-204 |year= 2002 |pmid= 12107411 |doi= }}
* {{cite journal | vauthors = Yin W, Cheepala S, Clifford JL | title = Identification of a novel splice variant of X-linked inhibitor of apoptosis-associated factor 1 | journal = Biochem. Biophys. Res. Commun. | volume = 339 | issue = 4 | pages = 1148–54 | year = 2006 | pmid = 16343440 | doi = 10.1016/j.bbrc.2005.11.128 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
* {{cite journal | vauthors = Fang X, Liu Z, Fan Y, Zheng C, Nilson S, Egevad L, Ekman P, Xu D | title = Switch to full-length of XAF1 mRNA expression in prostate cancer cells by the DNA methylation inhibitor | journal = Int. J. Cancer | volume = 118 | issue = 10 | pages = 2485–9 | year = 2006 | pmid = 16353137 | doi = 10.1002/ijc.21636 }}
*{{cite journal | author=Byun DS, Cho K, Ryu BK, ''et al.'' |title=Hypermethylation of XIAP-associated factor 1, a putative tumor suppressor gene from the 17p13.2 locus, in human gastric adenocarcinomas. |journal=Cancer Res. |volume=63 |issue= 21 |pages= 7068-75 |year= 2004 |pmid= 14612497 |doi= }}
* {{cite journal | vauthors = Gilli F, Marnetto F, Caldano M, Sala A, Malucchi S, Capobianco M, Bertolotto A | title = Biological markers of interferon-beta therapy: comparison among interferon-stimulated genes MxA, TRAIL and XAF-1 | journal = Mult. Scler. | volume = 12 | issue = 1 | pages = 47–57 | year = 2006 | pmid = 16459719 | doi = 10.1191/135248506ms1245oa }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
* {{cite journal | vauthors = Reu FJ, Bae SI, Cherkassky L, Leaman DW, Lindner D, Beaulieu N, MacLeod AR, Borden EC | title = Overcoming resistance to interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation | journal = J. Clin. Oncol. | volume = 24 | issue = 23 | pages = 3771–9 | year = 2006 | pmid = 16801630 | doi = 10.1200/JCO.2005.03.4074 }}
*{{cite journal | author=Ng KC, Campos EI, Martinka M, Li G |title=XAF1 expression is significantly reduced in human melanoma. |journal=J. Invest. Dermatol. |volume=123 |issue= 6 |pages= 1127-34 |year= 2005 |pmid= 15610524 |doi= 10.1111/j.0022-202X.2004.23467.x }}
* {{cite journal | vauthors = Lee MG, Huh JS, Chung SK, Lee JH, Byun DS, Ryu BK, Kang MJ, Chae KS, Lee SJ, Lee CH, Kim JI, Chang SG, Chi SG | title = Promoter CpG hypermethylation and downregulation of XAF1 expression in human urogenital malignancies: implication for attenuated p53 response to apoptotic stresses | journal = Oncogene | volume = 25 | issue = 42 | pages = 5807–22 | year = 2006 | pmid = 16909101 | doi = 10.1038/sj.onc.1209867 }}
*{{cite journal | author=Wang J, He H, Yu L, ''et al.'' |title=HSF1 down-regulates XAF1 through transcriptional regulation. |journal=J. Biol. Chem. |volume=281 |issue= 5 |pages= 2451-9 |year= 2006 |pmid= 16303760 |doi= 10.1074/jbc.M505890200 }}
* {{cite journal | vauthors = Zou B, Chim CS, Zeng H, Leung SY, Yang Y, Tu SP, Lin MC, Wang J, He H, Jiang SH, Sun YW, Yu LF, Yuen ST, Kung HF, Wong BC | title = Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers | journal = Gastroenterology | volume = 131 | issue = 6 | pages = 1835–43 | year = 2006 | pmid = 17087954 | doi = 10.1053/j.gastro.2006.09.050 }}
*{{cite journal | author=Yin W, Cheepala S, Clifford JL |title=Identification of a novel splice variant of X-linked inhibitor of apoptosis-associated factor 1. |journal=Biochem. Biophys. Res. Commun. |volume=339 |issue= 4 |pages= 1148-54 |year= 2006 |pmid= 16343440 |doi= 10.1016/j.bbrc.2005.11.128 }}
* {{cite journal | vauthors = Micali OC, Cheung HH, Plenchette S, Hurley SL, Liston P, LaCasse EC, Korneluk RG | title = Silencing of the XAF1 gene by promoter hypermethylation in cancer cells and reactivation to TRAIL-sensitization by IFN-beta | journal = BMC Cancer | volume = 7 | pages = 52 | year = 2007 | pmid = 17376236 | pmc = 1845166 | doi = 10.1186/1471-2407-7-52 }}
*{{cite journal | author=Fang X, Liu Z, Fan Y, ''et al.'' |title=Switch to full-length of XAF1 mRNA expression in prostate cancer cells by the DNA methylation inhibitor. |journal=Int. J. Cancer |volume=118 |issue= 10 |pages= 2485-9 |year= 2006 |pmid= 16353137 |doi= 10.1002/ijc.21636 }}
* {{cite journal | vauthors = Kempkensteffen C, Hinz S, Schrader M, Christoph F, Magheli A, Krause H, Schostak M, Miller K, Weikert S | title = Gene expression and promoter methylation of the XIAP-associated Factor 1 in renal cell carcinomas: correlations with pathology and outcome | journal = Cancer Lett. | volume = 254 | issue = 2 | pages = 227–35 | year = 2007 | pmid = 17449173 | doi = 10.1016/j.canlet.2007.03.006 }}
*{{cite journal | author=Gilli F, Marnetto F, Caldano M, ''et al.'' |title=Biological markers of interferon-beta therapy: comparison among interferon-stimulated genes MxA, TRAIL and XAF-1. |journal=Mult. Scler. |volume=12 |issue= 1 |pages= 47-57 |year= 2006 |pmid= 16459719 |doi= }}
* {{cite journal | vauthors = Shibata T, Mahotka C, Wethkamp N, Heikaus S, Gabbert HE, Ramp U | title = Disturbed expression of the apoptosis regulators XIAP, XAF1, and Smac/DIABLO in gastric adenocarcinomas | journal = Diagn. Mol. Pathol. | volume = 16 | issue = 1 | pages = 1–8 | year = 2007 | pmid = 17471152 | doi = 10.1097/01.pdm.0000213471.92925.51 }}
*{{cite journal  | author=Reu FJ, Bae SI, Cherkassky L, ''et al.'' |title=Overcoming resistance to interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation. |journal=J. Clin. Oncol. |volume=24 |issue= 23 |pages= 3771-9 |year= 2006 |pmid= 16801630 |doi= 10.1200/JCO.2005.03.4074 }}
* {{cite journal | vauthors = Chung SK, Lee MG, Ryu BK, Lee JH, Han J, Byun DS, Chae KS, Lee KY, Jang JY, Kim HJ, Chi SG | title = Frequent alteration of XAF1 in human colorectal cancers: implication for tumor cell resistance to apoptotic stresses | journal = Gastroenterology | volume = 132 | issue = 7 | pages = 2459–77 | year = 2007 | pmid = 17570219 | doi = 10.1053/j.gastro.2007.04.024 }}
*{{cite journal | author=Lee MG, Huh JS, Chung SK, ''et al.'' |title=Promoter CpG hypermethylation and downregulation of XAF1 expression in human urogenital malignancies: implication for attenuated p53 response to apoptotic stresses. |journal=Oncogene |volume=25 |issue= 42 |pages= 5807-22 |year= 2006 |pmid= 16909101 |doi= 10.1038/sj.onc.1209867 }}
* {{cite journal | vauthors = Arora V, Cheung HH, Plenchette S, Micali OC, Liston P, Korneluk RG | title = Degradation of survivin by the X-linked inhibitor of apoptosis (XIAP)-XAF1 complex | journal = J. Biol. Chem. | volume = 282 | issue = 36 | pages = 26202–9 | year = 2007 | pmid = 17613533 | doi = 10.1074/jbc.M700776200 }}
*{{cite journal | author=Zou B, Chim CS, Zeng H, ''et al.'' |title=Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers. |journal=Gastroenterology |volume=131 |issue= 6 |pages= 1835-43 |year= 2007 |pmid= 17087954 |doi= 10.1053/j.gastro.2006.09.050 }}
*{{cite journal | author=Micali OC, Cheung HH, Plenchette S, ''et al.'' |title=Silencing of the XAF1 gene by promoter hypermethylation in cancer cells and reactivation to TRAIL-sensitization by IFN-beta. |journal=BMC Cancer |volume=7 |issue=  |pages= 52 |year= 2007 |pmid= 17376236 |doi= 10.1186/1471-2407-7-52 }}
*{{cite journal  | author=Kempkensteffen C, Hinz S, Schrader M, ''et al.'' |title=Gene expression and promoter methylation of the XIAP-associated Factor 1 in renal cell carcinomas: correlations with pathology and outcome. |journal=Cancer Lett. |volume=254 |issue= 2 |pages= 227-35 |year= 2007 |pmid= 17449173 |doi= 10.1016/j.canlet.2007.03.006 }}
*{{cite journal  | author=Shibata T, Mahotka C, Wethkamp N, ''et al.'' |title=Disturbed expression of the apoptosis regulators XIAP, XAF1, and Smac/DIABLO in gastric adenocarcinomas. |journal=Diagn. Mol. Pathol. |volume=16 |issue= 1 |pages= 1-8 |year= 2007 |pmid= 17471152 |doi= 10.1097/01.pdm.0000213471.92925.51 }}
*{{cite journal  | author=Chung SK, Lee MG, Ryu BK, ''et al.'' |title=Frequent alteration of XAF1 in human colorectal cancers: implication for tumor cell resistance to apoptotic stresses. |journal=Gastroenterology |volume=132 |issue= 7 |pages= 2459-77 |year= 2007 |pmid= 17570219 |doi= 10.1053/j.gastro.2007.04.024 }}
*{{cite journal  | author=Arora V, Cheung HH, Plenchette S, ''et al.'' |title=Degradation of survivin by the X-linked inhibitor of apoptosis (XIAP)-XAF1 complex. |journal=J. Biol. Chem. |volume=282 |issue= 36 |pages= 26202-9 |year= 2007 |pmid= 17613533 |doi= 10.1074/jbc.M700776200 }}
}}
{{refend}}
{{refend}}


{{protein-stub}}
 
{{WikiDoc Sources}}
{{gene-17-stub}}

Latest revision as of 12:12, 2 November 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

XIAP-associated factor 1 is a protein that in humans is encoded by the XAF1 gene.[1][2][3]

Function

X-linked inhibitor of apoptosis (XIAP; MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases (e.g., CASP3; MIM 600636). XIAP has 3 BIR domains and a C-terminal RING zinc finger that possesses E3 ubiquitin ligase (see MIM 601623) activity. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells (Liston et al., 2001).[supplied by OMIM][3]

Interactions

XAF1 has been shown to interact with XIAP.[2]

References

  1. ↑ Leaman DW, Chawla-Sarkar M, Vyas K, Reheman M, Tamai K, Toji S, Borden EC (Aug 2002). "Identification of X-linked inhibitor of apoptosis-associated factor-1 as an interferon-stimulated gene that augments TRAIL Apo2L-induced apoptosis". J. Biol. Chem. 277 (32): 28504–11. doi:10.1074/jbc.M204851200. PMID 12029096.
  2. ↑ 2.0 2.1 Liston P, Fong WG, Kelly NL, Toji S, Miyazaki T, Conte D, Tamai K, Craig CG, McBurney MW, Korneluk RG (Feb 2001). "Identification of XAF1 as an antagonist of XIAP anti-Caspase activity". Nat. Cell Biol. 3 (2): 128–33. doi:10.1038/35055027. PMID 11175744.
  3. ↑ 3.0 3.1 "Entrez Gene: XAF1 XIAP associated factor-1".

Further reading

  • Fong WG, Liston P, Rajcan-Separovic E, St Jean M, Craig C, Korneluk RG (2000). "Expression and genetic analysis of XIAP-associated factor 1 (XAF1) in cancer cell lines". Genomics. 70 (1): 113–22. doi:10.1006/geno.2000.6364. PMID 11087668.
  • Wistow G, Bernstein SL, Wyatt MK, Ray S, Behal A, Touchman JW, Bouffard G, Smith D, Peterson K (2002). "Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts". Mol. Vis. 8: 196–204. PMID 12107411.
  • Byun DS, Cho K, Ryu BK, Lee MG, Kang MJ, Kim HR, Chi SG (2003). "Hypermethylation of XIAP-associated factor 1, a putative tumor suppressor gene from the 17p13.2 locus, in human gastric adenocarcinomas". Cancer Res. 63 (21): 7068–75. PMID 14612497.
  • Ng KC, Campos EI, Martinka M, Li G (2004). "XAF1 expression is significantly reduced in human melanoma". J. Invest. Dermatol. 123 (6): 1127–34. doi:10.1111/j.0022-202X.2004.23467.x. PMID 15610524.
  • Wang J, He H, Yu L, Xia HH, Lin MC, Gu Q, Li M, Zou B, An X, Jiang B, Kung HF, Wong BC (2006). "HSF1 down-regulates XAF1 through transcriptional regulation". J. Biol. Chem. 281 (5): 2451–9. doi:10.1074/jbc.M505890200. PMID 16303760.
  • Yin W, Cheepala S, Clifford JL (2006). "Identification of a novel splice variant of X-linked inhibitor of apoptosis-associated factor 1". Biochem. Biophys. Res. Commun. 339 (4): 1148–54. doi:10.1016/j.bbrc.2005.11.128. PMID 16343440.
  • Fang X, Liu Z, Fan Y, Zheng C, Nilson S, Egevad L, Ekman P, Xu D (2006). "Switch to full-length of XAF1 mRNA expression in prostate cancer cells by the DNA methylation inhibitor". Int. J. Cancer. 118 (10): 2485–9. doi:10.1002/ijc.21636. PMID 16353137.
  • Gilli F, Marnetto F, Caldano M, Sala A, Malucchi S, Capobianco M, Bertolotto A (2006). "Biological markers of interferon-beta therapy: comparison among interferon-stimulated genes MxA, TRAIL and XAF-1". Mult. Scler. 12 (1): 47–57. doi:10.1191/135248506ms1245oa. PMID 16459719.
  • Reu FJ, Bae SI, Cherkassky L, Leaman DW, Lindner D, Beaulieu N, MacLeod AR, Borden EC (2006). "Overcoming resistance to interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation". J. Clin. Oncol. 24 (23): 3771–9. doi:10.1200/JCO.2005.03.4074. PMID 16801630.
  • Lee MG, Huh JS, Chung SK, Lee JH, Byun DS, Ryu BK, Kang MJ, Chae KS, Lee SJ, Lee CH, Kim JI, Chang SG, Chi SG (2006). "Promoter CpG hypermethylation and downregulation of XAF1 expression in human urogenital malignancies: implication for attenuated p53 response to apoptotic stresses". Oncogene. 25 (42): 5807–22. doi:10.1038/sj.onc.1209867. PMID 16909101.
  • Zou B, Chim CS, Zeng H, Leung SY, Yang Y, Tu SP, Lin MC, Wang J, He H, Jiang SH, Sun YW, Yu LF, Yuen ST, Kung HF, Wong BC (2006). "Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers". Gastroenterology. 131 (6): 1835–43. doi:10.1053/j.gastro.2006.09.050. PMID 17087954.
  • Micali OC, Cheung HH, Plenchette S, Hurley SL, Liston P, LaCasse EC, Korneluk RG (2007). "Silencing of the XAF1 gene by promoter hypermethylation in cancer cells and reactivation to TRAIL-sensitization by IFN-beta". BMC Cancer. 7: 52. doi:10.1186/1471-2407-7-52. PMC 1845166. PMID 17376236.
  • Kempkensteffen C, Hinz S, Schrader M, Christoph F, Magheli A, Krause H, Schostak M, Miller K, Weikert S (2007). "Gene expression and promoter methylation of the XIAP-associated Factor 1 in renal cell carcinomas: correlations with pathology and outcome". Cancer Lett. 254 (2): 227–35. doi:10.1016/j.canlet.2007.03.006. PMID 17449173.
  • Shibata T, Mahotka C, Wethkamp N, Heikaus S, Gabbert HE, Ramp U (2007). "Disturbed expression of the apoptosis regulators XIAP, XAF1, and Smac/DIABLO in gastric adenocarcinomas". Diagn. Mol. Pathol. 16 (1): 1–8. doi:10.1097/01.pdm.0000213471.92925.51. PMID 17471152.
  • Chung SK, Lee MG, Ryu BK, Lee JH, Han J, Byun DS, Chae KS, Lee KY, Jang JY, Kim HJ, Chi SG (2007). "Frequent alteration of XAF1 in human colorectal cancers: implication for tumor cell resistance to apoptotic stresses". Gastroenterology. 132 (7): 2459–77. doi:10.1053/j.gastro.2007.04.024. PMID 17570219.
  • Arora V, Cheung HH, Plenchette S, Micali OC, Liston P, Korneluk RG (2007). "Degradation of survivin by the X-linked inhibitor of apoptosis (XIAP)-XAF1 complex". J. Biol. Chem. 282 (36): 26202–9. doi:10.1074/jbc.M700776200. PMID 17613533.


Retrieved from "https://www.wikidoc.org/index.php?title=XAF1&oldid=1418005"