Cirrhosis classification: Difference between revisions
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===Macronodular=== | ===Macronodular=== | ||
Macronodular cirrhosis is characterized by nodules that are more than 3mm in diameter, and | Macronodular cirrhosis is characterized by nodules that are more than 3mm in diameter, and can be caused by | ||
* Chronic [[viral hepatitis]] | |||
*Hemochromatosis | |||
*[[Wilson's disease]] | |||
*Post-necrotic cirrhosis | |||
===Mixed=== | ===Mixed=== | ||
It has been shown that micronodular cirrhosis can often progress into macronodular cirrhosis. During this transformation, a mixed form of cirrhosis may be seen. <ref name="pmid6629323">{{cite journal| author=Fauerholdt L, Schlichting P, Christensen E, Poulsen H, Tygstrup N, Juhl E| title=Conversion of micronodular cirrhosis into macronodular cirrhosis. | journal=Hepatology | year= 1983 | volume= 3 | issue= 6 | pages= 928-31 | pmid=6629323 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6629323 }} </ref> | It has been shown that micronodular cirrhosis can often progress into macronodular cirrhosis. During this transformation, a mixed form of cirrhosis may be seen. <ref name="pmid6629323">{{cite journal| author=Fauerholdt L, Schlichting P, Christensen E, Poulsen H, Tygstrup N, Juhl E| title=Conversion of micronodular cirrhosis into macronodular cirrhosis. | journal=Hepatology | year= 1983 | volume= 3 | issue= 6 | pages= 928-31 | pmid=6629323 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6629323 }} </ref> Mixed nodular cirrhosis is also seen in Indian childhood cirrhosis. <ref name="pmid47794">{{cite journal| author=Nayak NC, Ramalingaswami V| title=Indian childhood cirrhosis. | journal=Clin Gastroenterol | year= 1975 | volume= 4 | issue= 2 | pages= 333-49 | pmid=47794 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=47794 }} </ref> | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 18:30, 6 September 2012
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Cirrhosis classification On the Web |
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Risk calculators and risk factors for Cirrhosis classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Charmaine Patel, M.D. [2]
Overview
Classification Based on Morphology
Cirrhosis has historically been classified upon the nodular morphology that is seen on upon the gross appearance of the liver. Accurate assessment of the liver morphology can only be obtained through surgery, biopsy, or autopsy, therefore more recently, more non-invasive means of classifying and determining the causes of cirrhosis are used.
Micronodular
Micronodular cirrhosis is characterized by nodules that are less than 3mm in diameter, and is caused by:
- Alcohol
- Hemochromatosis
- Cholestatic causes of cirrhosis
- Hepatic venous outflow obstruction
Macronodular
Macronodular cirrhosis is characterized by nodules that are more than 3mm in diameter, and can be caused by
- Chronic viral hepatitis
- Hemochromatosis
- Wilson's disease
- Post-necrotic cirrhosis
Mixed
It has been shown that micronodular cirrhosis can often progress into macronodular cirrhosis. During this transformation, a mixed form of cirrhosis may be seen. [1] Mixed nodular cirrhosis is also seen in Indian childhood cirrhosis. [2]
References
- ↑ Fauerholdt L, Schlichting P, Christensen E, Poulsen H, Tygstrup N, Juhl E (1983). "Conversion of micronodular cirrhosis into macronodular cirrhosis". Hepatology. 3 (6): 928–31. PMID 6629323.
- ↑ Nayak NC, Ramalingaswami V (1975). "Indian childhood cirrhosis". Clin Gastroenterol. 4 (2): 333–49. PMID 47794.