Aspiration pneumonia bacterial infection medical therapy: Difference between revisions
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'''Editor(s)-in-Chief:''' [[C. Michael Gibson, M.S., M.D.]] [mailto:mgibson@perfuse.org] Phone:617-632-7753; '''Associate Editor(s)-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.D.]] [mailto:psingh@perfuse.org] | '''Editor(s)-in-Chief:''' [[C. Michael Gibson, M.S., M.D.]] [mailto:mgibson@perfuse.org] Phone:617-632-7753; '''Associate Editor(s)-In-Chief:''' [[Priyamvada Singh|Priyamvada Singh, M.D.]] [mailto:psingh@perfuse.org] | ||
==Overview== | ==Overview== | ||
===Medical therapy=== | |||
====Antibiotics==== | |||
* Treatment of choice [[clindamycin]] | |||
** Doses 600 mg Q8hourly, followed by 300 mg Q6hourly, or 450 mg tid | |||
** Advantage of clindamycin : | |||
*** Cheap | |||
*** Less incidences of superimposed [[MRSA]] | |||
* Other agents used: [[Ampicillin-sulbactam]] (1.5 g or 3 g twice daily), [[Imipenem]] ([[Invanz]] 500 mg BID), [[amoxicillin]]-[[clavulnate]] (875 mg orally bid), [[penicillin]] (1 to 2 million units IV Q6hourly) / amoxicillin (500 mg orally tid)+ [[metronidazole]] (500 mg orally or IV tid). | |||
* Monotherapy with metronidazole is not preferred as high failure rates have been reported. This is because metronidazole is ineffective against some pathogens such as microaerophilic and aerobic streptococci | |||
==References== | ==References== | ||
Revision as of 19:22, 8 September 2012
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Aspiration pneumonia bacterial infection Microchapters |
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Differentiating Aspiration pneumonia bacterial infection from other Diseases |
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Diagnosis |
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Treatment |
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Aspiration pneumonia bacterial infection medical therapy On the Web |
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Editor(s)-in-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-632-7753; Associate Editor(s)-In-Chief: Priyamvada Singh, M.D. [2]
Overview
Medical therapy
Antibiotics
- Treatment of choice clindamycin
- Doses 600 mg Q8hourly, followed by 300 mg Q6hourly, or 450 mg tid
- Advantage of clindamycin :
- Cheap
- Less incidences of superimposed MRSA
- Other agents used: Ampicillin-sulbactam (1.5 g or 3 g twice daily), Imipenem (Invanz 500 mg BID), amoxicillin-clavulnate (875 mg orally bid), penicillin (1 to 2 million units IV Q6hourly) / amoxicillin (500 mg orally tid)+ metronidazole (500 mg orally or IV tid).
- Monotherapy with metronidazole is not preferred as high failure rates have been reported. This is because metronidazole is ineffective against some pathogens such as microaerophilic and aerobic streptococci