Chronic myelogenous leukemia epidemiology and demographics: Difference between revisions

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==Overview==
==Overview==
Chronic myelogenous leukemia (CML) occurs in all age groups, but most commonly in the middle-aged and elderly. CML affects slightly more men than women. CML represents about 15&ndash;20% of all cases of adult leukemia in Western populations.<ref name="Faderl1990">{{cite journal|title=Chronic myelogenous leukemia: biology and therapy.|author=Faderl S, Talpaz M, Estrov Z, Kantarjian HM|journal=Annals of Internal Medicine|date=1999|volume=131|issue=3|pages=207-219|pmid=10428738}}</ref>


==Epidemiology==
==Epidemiology==
CML occurs in all age groups, but most commonly in the middle-aged and elderly. Its annual [[incidence (epidemiology)|incidence]] is 1&ndash;2 per 100,000 people, and slightly more men than women are affected. CML represents about 15&ndash;20% of all cases of adult leukemia in Western populations.<ref name="Faderl1990">{{cite journal|title=Chronic myelogenous leukemia: biology and therapy.|author=Faderl S, Talpaz M, Estrov Z, Kantarjian HM|journal=Annals of Internal Medicine|date=1999|volume=131|issue=3|pages=207-219|pmid=10428738}}</ref> The only well-described risk factor for CML is exposure to [[ionizing radiation]]; for example, increased rates of CML were seen in people exposed to the atomic bombings of Hiroshima and Nagasaki.<ref>{{cite journal|title=Radiogenic leukemia revisited|author=Moloney WC|date=1987|journal=Blood|volume=70|issue=4|pages=905-908|pmid=3477299}}</ref>
 


==References==
==References==

Revision as of 18:18, 12 June 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Chronic myelogenous leukemia (CML) occurs in all age groups, but most commonly in the middle-aged and elderly. CML affects slightly more men than women. CML represents about 15–20% of all cases of adult leukemia in Western populations.[1]

Epidemiology

References

  1. Faderl S, Talpaz M, Estrov Z, Kantarjian HM (1999). "Chronic myelogenous leukemia: biology and therapy". Annals of Internal Medicine. 131 (3): 207–219. PMID 10428738.


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