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'''Islet cell carcinoma''' or '''nesidioblastoma''' is an uncommon [[cancer]] of the endocrine [[pancreas]].
'''Islet cell carcinoma''' or '''nesidioblastoma''' is an uncommon [[cancer]] of the endocrine [[pancreas]]. It accounts for approximately 1.3% of [[pancreatic cancer]].<ref name="pmid17896148">{{cite journal |author=Yao JC, Eisner MP, Leary C, ''et al'' |title=Population-based study of islet cell carcinoma |journal=Ann. Surg. Oncol. |volume=14 |issue=12 |pages=3492–500 |year=2007 |month=Dec |pmid=17896148 |pmc=2077912 |doi=10.1245/s10434-007-9566-6 }}</ref>. The term "nesidioblastoma" dates to at least 1938.<ref>{{cite journal |author=Laidlaw GF |title=Nesidioblastoma, the islet tumor of the pancreas |journal=Am J Pathol. |volume=14 |issue=2 |pages=125–34 |year=1938 |pmc=1964945}}</ref> The term "nesidioblastoma" dates to at least 1938.<ref>{{cite journal |author=Laidlaw GF |title=Nesidioblastoma, the islet tumor of the pancreas |journal=Am J Pathol. |volume=14 |issue=2 |pages=125–34 |year=1938 |pmc=1964945 |pmid=19970380}}</ref>


It accounts for approximately 1.3% of [[pancreatic cancer]].<ref name="pmid17896148">{{cite journal |author=Yao JC, Eisner MP, Leary C, ''et al'' |title=Population-based study of islet cell carcinoma |journal=Ann. Surg. Oncol. |volume=14 |issue=12 |pages=3492–500 |year=2007 |month=Dec |pmid=17896148 |pmc=2077912 |doi=10.1245/s10434-007-9566-6 }}</ref>
==Survival==
Survival in islet cell carcinoma is highly dependent upon the degree of disease involvement; surgical cure is possible if the tumor is resected completely. Review articles using the [[Surveillance Epidemiology and End Results]] (SEER) national database have shown a median survival of about a decade for localized disease, six years for regional (confined to the region of the pancreas) and two years for those with distant disease.<ref>[http://www.asco.org/portal/site/ASCO/menuitem.34d60f5624ba07fd506fe310ee37a01d/?vgnextoid=76f8201eb61a7010VgnVCM100000ed730ad1RCRD&vmview=abst_detail_view&confID=47&abstractID=35623 American Society of Clinical Oncology.]</ref>


The term "nesidioblastoma" dates to at least 1938.<ref>{{cite journal |author=Laidlaw GF |title=Nesidioblastoma, the islet tumor of the pancreas |journal=Am J Pathol. |volume=14 |issue=2 |pages=125–34 |year=1938 |pmc=1964945}}</ref>


==See also==
==See also==

Revision as of 17:32, 12 September 2012

Islet-cell carcinoma
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MeSH D018273

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Islet cell carcinoma or nesidioblastoma is an uncommon cancer of the endocrine pancreas. It accounts for approximately 1.3% of pancreatic cancer.[1]. The term "nesidioblastoma" dates to at least 1938.[2] The term "nesidioblastoma" dates to at least 1938.[3]

Survival

Survival in islet cell carcinoma is highly dependent upon the degree of disease involvement; surgical cure is possible if the tumor is resected completely. Review articles using the Surveillance Epidemiology and End Results (SEER) national database have shown a median survival of about a decade for localized disease, six years for regional (confined to the region of the pancreas) and two years for those with distant disease.[4]


See also

References

  1. Yao JC, Eisner MP, Leary C; et al. (2007). "Population-based study of islet cell carcinoma". Ann. Surg. Oncol. 14 (12): 3492–500. doi:10.1245/s10434-007-9566-6. PMC 2077912. PMID 17896148. Unknown parameter |month= ignored (help)
  2. Laidlaw GF (1938). "Nesidioblastoma, the islet tumor of the pancreas". Am J Pathol. 14 (2): 125–34. PMC 1964945.
  3. Laidlaw GF (1938). "Nesidioblastoma, the islet tumor of the pancreas". Am J Pathol. 14 (2): 125–34. PMC 1964945. PMID 19970380.
  4. American Society of Clinical Oncology.

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