Langerhans cell histiocytosis medical therapy: Difference between revisions
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Revision as of 20:46, 13 September 2012
Langerhans cell histiocytosis Microchapters |
Differentiating Langerhans cell histiocytosis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Treatment
Treatment is guided by extent of disease.
- Solitary bone lesion may be amenable through excision or limited radiation. However systemic disease often require chemotherapy.
- Use of systemic steroid is common, singly or adjunct to chemotherapy. Local steroid cream is applied to skin lesions.
- Endocrine deficiency often require lifelong suppliment e.g. desmopressin for diabates insipidus which can be applied as nasal drop.
- Chemotherapeutic agents such as alkylating agents, antimetabolites, vinca alkaloids either singly or in combination can lead to complete remission in diffuse disease.