Sepsis causes: Difference between revisions
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==Causes== | ==Causes== | ||
Sepsis is caused by a bacterial infection that can begin anywhere in the body. Common places where an infection might start include: | Sepsis is caused by a bacterial infection that can begin anywhere in the body. Common places where an infection might start include: | ||
*The bowel (usually seen with [[peritonitis]]) | *The [[bowel]] (usually seen with [[peritonitis]]) | ||
*The kidneys (upper urinary tract infection or [[pyelonephritis]]) | *The [[kidneys]] (upper urinary tract infection or [[pyelonephritis]]) | ||
*The lining of the brain ([[meningitis]]) | *The lining of the brain ([[meningitis]]) | ||
*The liver or the gall bladder ([[cholecystitis]]) | *The [[liver]] or the [[gall bladder]] ([[cholecystitis]]) | ||
*The lungs (bacterial [[pneumonia]]) | *The [[lungs]] (bacterial [[pneumonia]]) | ||
*The skin ([[cellulitis]]) | *The [[skin]] ([[cellulitis]]) | ||
*In children, sepsis may accompany infection of the bone ([[osteomyelitis]]). | *In children, sepsis may accompany infection of the [[bone]] ([[osteomyelitis]]). | ||
*In hospitalized patients, common sites of infection include [[intravenous lines]], [[surgical wounds]], [[surgical drains]], and sites of skin breakdown known as [[bedsores]] ([[decubitus ulcers]]) | *In hospitalized patients, common sites of infection include [[intravenous lines]], [[surgical wounds]], [[surgical drains]], and sites of skin breakdown known as [[bedsores]] ([[decubitus ulcers]]) | ||
Revision as of 13:23, 17 September 2012
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Sepsis Microchapters |
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Sepsis causes On the Web |
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American Roentgen Ray Society Images of Sepsis causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The process of infection by bacteria or fungi can result in systemic signs and symptoms that are variously described. In rough order of severity, these are bacteremia or fungemia; septicemia; sepsis, severe sepsis or sepsis syndrome; septic shock; refractory septic shock; multiple organ dysfunction syndrome, and death. The condition develops as a response to certain microbial molecules which trigger the production and release of cellular mediators, such as tumor necrosis factors (TNF); these act to stimulate immune response. Besides TNFα, other cytokines involved in the development of septic shock include interleukin-1β, and interferon γ.
Causes
Sepsis is caused by a bacterial infection that can begin anywhere in the body. Common places where an infection might start include:
- The bowel (usually seen with peritonitis)
- The kidneys (upper urinary tract infection or pyelonephritis)
- The lining of the brain (meningitis)
- The liver or the gall bladder (cholecystitis)
- The lungs (bacterial pneumonia)
- The skin (cellulitis)
- In children, sepsis may accompany infection of the bone (osteomyelitis).
- In hospitalized patients, common sites of infection include intravenous lines, surgical wounds, surgical drains, and sites of skin breakdown known as bedsores (decubitus ulcers)
Causes in Alphabetical Order
- Anthrax
- Gangrene
- Gram negative bacteremia
- Necrotizing enterocolitis
- Lemierre syndrome
- Melioidosis
- Neisseria meningiditis
- Peritonitis
- Pseudomonas aeruginosa
- Vibrio vulnificus