Sepsis history and symptoms: Difference between revisions
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==History and Symptoms== | ==History and Symptoms== | ||
Symptoms of sepsis are often related to the underlying infectious process. When the infection crosses into sepsis, the resulting symptoms are that of: | Symptoms of sepsis are often related to the underlying infectious process. When the infection crosses into sepsis, the resulting symptoms are that of: | ||
*[[Systemic inflammatory response syndrome]] (SIRS): | *[[Systemic inflammatory response syndrome]] (SIRS), which include: | ||
**General inflammation | **General [[inflammation]] | ||
**[[Fever]] | **[[Fever]] | ||
**Elevated [[white blood cell]] count ([[leukocytosis]]) | **Elevated [[white blood cell]] count ([[leukocytosis]]) | ||
**Raised heart rate ([[tachycardia]]) and breathing rate ([[tachypnea]]). | **Raised heart rate ([[tachycardia]]) and breathing rate ([[tachypnea]]). | ||
A capillary leak syndrome can develop with severe swelling | A capillary leak syndrome can develop with severe swelling, [[edema]], and third spacing of fluids. General symptoms can include flu like symptoms as well as shaking chills or [[rigors]]. | ||
The immunological response that causes sepsis is a systemic inflammatory response causing widespread activation of [[inflammation]] and [[coagulation]] pathways. This may progress to dysfunction of the [[septic shock|circulatory system]] and, even under optimal treatment, may result in the [[multiple organ dysfunction syndrome]] and eventually [[death]]. | The immunological response that causes sepsis is a systemic inflammatory response causing widespread activation of [[inflammation]] and [[coagulation]] pathways. This may progress to dysfunction of the [[septic shock|circulatory system]] and, even under optimal treatment, may result in the [[multiple organ dysfunction syndrome]] and eventually [[death]]. | ||
Revision as of 14:00, 17 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
History and Symptoms
Symptoms of sepsis are often related to the underlying infectious process. When the infection crosses into sepsis, the resulting symptoms are that of:
- Systemic inflammatory response syndrome (SIRS), which include:
- General inflammation
- Fever
- Elevated white blood cell count (leukocytosis)
- Raised heart rate (tachycardia) and breathing rate (tachypnea).
A capillary leak syndrome can develop with severe swelling, edema, and third spacing of fluids. General symptoms can include flu like symptoms as well as shaking chills or rigors.
The immunological response that causes sepsis is a systemic inflammatory response causing widespread activation of inflammation and coagulation pathways. This may progress to dysfunction of the circulatory system and, even under optimal treatment, may result in the multiple organ dysfunction syndrome and eventually death.