Myelofibrosis causes: Difference between revisions

	Myelofibrosis Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Myelofibrosis from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X-ray
Echocardiography and Ultrasound
CT scan
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Myelofibrosis causes On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Myelofibrosis causes All Images X-rays Echo and Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Myelofibrosis causes
CDC on Myelofibrosis causes
Myelofibrosis causes in the news
Blogs on Myelofibrosis causes
Directions to Hospitals Treating Myelofibrosis
Risk calculators and risk factors for Myelofibrosis causes

Revision as of 13:35, 14 August 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Bone marrow is the soft, fatty tissue inside bones, responsible for hematopoiesis. Stem cells are immature cells in the bone marrow that give rise to all of your blood cells. Blood is made of:

Scarring of the bone marrow means the marrow is not able to make enough blood cells. Anemia, bleeding tendency, and a higher risk of infections may occur.

As a result, the liver and spleen make some of these blood cells. This causes these organs to swell, which is called extramedullary hematopoiesis.

The cause of myelofibrosis is unknown. There are no known risk factors. The disorder usually develops slowly in people over age 50.

Diseases such as leukemia and lymphoma may also cause bone marrow scarring. This is called secondary myelofibrosis.

@@ Line 5: / Line 5: @@
 ==Overview==
 ==Causes==
-*Bone marrow is the soft, fatty tissue inside your bones. Stem cells are immature cells in the bone marrow that give rise to all of your blood cells. Your blood is made of:
+*Bone marrow is the soft, fatty tissue inside bones, responsible for hematopoiesis. Stem cells are immature cells in the bone marrow that give rise to all of your blood cells. Blood is made of:
-:*Red blood cells (which carry oxygen to your tissues)
+:*Red blood cells (which carry oxygen to tissues)
-:*White blood cells (which fight infection)
+:*White blood cells (which fight infections)
-:*Platelets (which help your blood clot)
+:*Platelets (which help blood clot)
-*Scarring of the bone marrow means the marrow is not able to make enough blood cells. Anemia, bleeding problems, and a higher risk of infections may occur.
+*Scarring of the bone marrow means the marrow is not able to make enough blood cells. Anemia, bleeding tendency, and a higher risk of infections may occur.
-*As a result, the liver and spleen try to make some of these blood cells. This causes these organs to swell, which is called extramedullary hematopoiesis.
+*As a result, the liver and spleen make some of these blood cells. This causes these organs to swell, which is called extramedullary hematopoiesis.
 *The cause of myelofibrosis is unknown. There are no known risk factors. The disorder usually develops slowly in people over age 50.