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{{Sheehan's syndrome}}
{{Sheehan's syndrome}}
{{CMG}}
{{CMG}}; {{AE}}
 
==Overview==
==Overview==
==Pathophysiology==
Hypertrophy and hyperplasia of [[lactotrophs]] during pregnancy results in the enlargement of the [[anterior pituitary]], without a corresponding increase in blood supply.


Secondly, the anterior pituitary is supplied by a low pressure [[portal venous system]].
==Historical Perspective==
 
===Discovery===
*[Disease name] was first discovered by [name of scientist], a [nationality + occupation], in [year]/during/following [event].
 
*The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
*In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
*In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].


These vulnerabilities, when affected by major [[hemorrhage]] or hypotension during the peripartum period, can result in [[ischaemia]] of the affected pituitary regions leading to [[necrosis]].
==Outbreaks==
*There have been several outbreaks of [disease name], which are summarized below:


The [[posterior pituitary]] is usually not affected due to its direct arterial supply.
==Landmark Events in the Development of Treatment Strategies==
*In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].
 
==Impact on Cultural History==
 
 
==Famous Cases==
*The following are a few famous cases of [[disease name]]:
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}


[[Category:Disease]]
{{WH}}
[[Category:Obstetrics]]
{{WS}}
[[Category:Endocrinology]]
 
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Revision as of 21:10, 3 August 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Historical Perspective

Discovery

  • [Disease name] was first discovered by [name of scientist], a [nationality + occupation], in [year]/during/following [event].
  • The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
  • In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
  • In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].

Outbreaks

  • There have been several outbreaks of [disease name], which are summarized below:

Landmark Events in the Development of Treatment Strategies

  • In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].

Impact on Cultural History

Famous Cases

References

Template:WH Template:WS