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{{Silent thyroiditis}}
{{Silent thyroiditis}}
{{CMG}}
{{CMG}} {{AE}} {{MMF}}
 
==Overview==
==Overview==
==History and Symptoms==
The hallmark of [[de Quervain's thyroiditis]] is [[hyperthyroidism]] with the neck pain. A positive history of [[viral illness]] and family history of de Quervain's thyroiditis are suggestive of de Quervain's thyroiditis. The most common symptoms of de Quervain's thyroiditis are [[neck pain]], [[palpitations]], [[tachycardia]], [[nervousness]], and [[tremors]].
Silent thyroiditis features a small [[Goitre|goiter]] without tenderness and, like the other types of resolving thyroiditis, tends to have a phase of [[hyperthyroidism]] followed by a phase of [[hypothyroidism]] then a return to euthyroidism.<ref>NIH Medline Plus [http://www.nlm.nih.gov/MEDLINEPLUS/ency/article/000388.htm]</ref> The time span of each phase is not concrete, but the hypo- phase usually lasts 2-3 months.
==History and symptoms==
 
=== History ===
Patients with [[de Quervain's thyroiditis]] usually have the history of [[viral]] [[illness]] and [[family history]] of [[de Quervain's thyroiditis]]. Patients may have the history of [[low-grade fever]] and viral flu-like symptoms, such as [[sore throat]], [[myalgia]], [[arthralgia]], and [[malaise]].
 
===Symptoms===
===Common Symptoms===
Common symptoms of de Quervain's thyroiditis include:<ref name="pmid25905408">{{cite journal |vauthors=De Groot LJ, Chrousos G, Dungan K, Feingold KR, Grossman A, Hershman JM, Koch C, Korbonits M, McLachlan R, New M, Purnell J, Rebar R, Singer F, Vinik A, Shrestha RT, Hennessey J |title= |journal= |volume= |issue= |pages= |year= |pmid=25905408 |doi= |url=}}</ref>
*Symptoms of preceding [[upper respiratory infection]]
**[[Malaise]]
**[[Myalgia]]
**[[Sore throat]]
*[[Fever]]
*Painful [[Thyroid mass causes|thyroid swelling]]
*Symptoms of [[thyrotoxicosis]]
**[[Tremors]]
**[[Nervousness]]
**[[Sweating]]
 
===Symptoms according to the disease stage===
[[De Quervain's thyroiditis]] usually causes [[hyperthyroidism]] in its acute phase. However, it can also cause [[hypothyroidism]] in some cases.<ref name="urlThyroiditis — NEJM">{{cite web |url=http://www.nejm.org/doi/full/10.1056/NEJMra021194 |title=Thyroiditis — NEJM |format= |work= |accessdate=}}</ref>
====Hyperthyroidism (in acute phase)====
Silent thyroiditis is usually presents with the symptoms of [[thyrotoxicosis]].
====General====
The patient may have the following general symptoms:
*[[Myalgia|Myalgias]]
*[[Low-grade fever]]
*[[Fatigue]]
*[[Weight loss]]
 
====Localized====
The patient may have:
*[[Neck pain|Severe neck pain]]
*Radiation of pain to the ears and/or jaw
*Neck swelling
 
====Gastrointestinal system====
The patient may have:
* [[Diarrhea]]
 
====Cardiovascular system====
The patient may have:
*[[Palpitation|Palpitations]]
 
====Neuro-psychiatric system====
The patient may have:
*[[Nervousness]]
*[[Irritability]]
*[[Tremors]]
 
====Skin and appendages====
The patient may have:
*[[Sweating]]


The symptoms are those of hyperthyroidism and hypothyroidism during these phases.
===Hypothyroidism (in later stage)===
The symptoms of [[hypothyroidism]] may develop in the later stages of silent thyroiditis during the recovery of thyrotoxicosis.
====General====
The patient may have:
* [[Fatigue]] 
* [[Lethargy]]
* Cold intolerance
* [[Myxedema]]
* [[Weight gain]]
* [[Weight loss]]
* [[Migraine]]s
* Puffy face


The earliest symptoms result from an overactive thyroid gland (hyperthyroidism). These symptoms may last for 3 months or fewer. Later symptoms may be of an underactive thyroid (including fatigue and cold intolerance) until the thyroid recovers.
====Localized symptoms====
The patient may have:
*Enlarged neck or presence of [[goiter]]
*[[Dysphonia]] (from involvement of the [[recurrent laryngeal nerve]])
*[[Dyspnea]] (from the [[Tracheal compression|compression of the trachea]])
*[[Dysphagia]] (from impingement upon the [[esophagus]])
* Small or shrunken [[thyroid gland]] (late in the [[disease]])


Symptoms are usually mild and may include:
====Gastrointestinal system====
The patient may have:
* [[Constipation]]
====Skin and appendages====
The patient may have:
* [[Dry skin]]
* [[Hair loss]]
====Neuro-psychiatric system====
The patient may have:
* [[Depression]]
* Difficulty concentrating or thinking
* [[Mania]]
* [[Memory loss]]
* [[Panic attack]]s
====Reproductive system====
The patient may have:
* [[Infertility]]
*[[Oligomenorrhea]]
*[[Menometrorrhagia]]
====Musculoskeletal====
The patient may have:
*[[Joint stiffness]]
*[[Muscle cramps]]


* [[Fatigue]]
* [[Frequent bowel movements]]
* [[Heat intolerance]]
* [[Increased appetite]]
* [[Increased sweating]]
* Irregular menstrual periods
* [[Irritability]]
* [[Muscle cramps]]
* [[Nervousness]], [[restlessness]]
* [[Palpitations]]
* [[Weakness]]
* [[Weight loss]]


==References==
==References==

Revision as of 17:24, 21 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]

Overview

The hallmark of de Quervain's thyroiditis is hyperthyroidism with the neck pain. A positive history of viral illness and family history of de Quervain's thyroiditis are suggestive of de Quervain's thyroiditis. The most common symptoms of de Quervain's thyroiditis are neck pain, palpitations, tachycardia, nervousness, and tremors.

History and symptoms

History

Patients with de Quervain's thyroiditis usually have the history of viral illness and family history of de Quervain's thyroiditis. Patients may have the history of low-grade fever and viral flu-like symptoms, such as sore throat, myalgia, arthralgia, and malaise.

Symptoms

Common Symptoms

Common symptoms of de Quervain's thyroiditis include:[1]

Symptoms according to the disease stage

De Quervain's thyroiditis usually causes hyperthyroidism in its acute phase. However, it can also cause hypothyroidism in some cases.[2]

Hyperthyroidism (in acute phase)

Silent thyroiditis is usually presents with the symptoms of thyrotoxicosis.

General

The patient may have the following general symptoms:

Localized

The patient may have:

Gastrointestinal system

The patient may have:

Cardiovascular system

The patient may have:

Neuro-psychiatric system

The patient may have:

Skin and appendages

The patient may have:

Hypothyroidism (in later stage)

The symptoms of hypothyroidism may develop in the later stages of silent thyroiditis during the recovery of thyrotoxicosis.

General

The patient may have:

Localized symptoms

The patient may have:

Gastrointestinal system

The patient may have:

Skin and appendages

The patient may have:

Neuro-psychiatric system

The patient may have:

Reproductive system

The patient may have:

Musculoskeletal

The patient may have:


References

  1. ↑ De Groot LJ, Chrousos G, Dungan K, Feingold KR, Grossman A, Hershman JM, Koch C, Korbonits M, McLachlan R, New M, Purnell J, Rebar R, Singer F, Vinik A, Shrestha RT, Hennessey J. PMID 25905408. Missing or empty |title= (help)
  2. ↑ "Thyroiditis — NEJM".


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