Congenital hypothyroidism natural history, complications and prognosis: Difference between revisions
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==Natural History== | ==Natural History== | ||
==Complications== | ==Complications== | ||
*Mental retardation | |||
*Growth retardation | |||
*Heart problems | |||
==Prognosis== | ==Prognosis== | ||
*Prognosis of congenital hypothyroidism depends on whether the baby starts thyroid hormone replacement therapy early. | |||
*The earlier the treatment begins, the better outcome the baby will be. | |||
Most children born with congenital hypothyroidism and correctly treated with thyroxine grow and develop normally in all respects. Even most of those with athyreosis and undetectable T<sub>4</sub> levels at birth develop with normal intelligence, although as a population academic performance tends to be below that of siblings and mild learning problems occur in some.<ref name="pmid8062543">{{cite journal |author=Moltz KC, Postellon DC |title=Congenital hypothyroidism and mental development |journal=Comprehensive therapy |volume=20 |issue=6 |pages=342-6 |year=1994 |pmid=8062543 |doi=}}</ref> | Most children born with congenital hypothyroidism and correctly treated with thyroxine grow and develop normally in all respects. Even most of those with athyreosis and undetectable T<sub>4</sub> levels at birth develop with normal intelligence, although as a population academic performance tends to be below that of siblings and mild learning problems occur in some.<ref name="pmid8062543">{{cite journal |author=Moltz KC, Postellon DC |title=Congenital hypothyroidism and mental development |journal=Comprehensive therapy |volume=20 |issue=6 |pages=342-6 |year=1994 |pmid=8062543 |doi=}}</ref> | ||
Revision as of 16:46, 20 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Natural History
Complications
- Mental retardation
- Growth retardation
- Heart problems
Prognosis
- Prognosis of congenital hypothyroidism depends on whether the baby starts thyroid hormone replacement therapy early.
- The earlier the treatment begins, the better outcome the baby will be.
Most children born with congenital hypothyroidism and correctly treated with thyroxine grow and develop normally in all respects. Even most of those with athyreosis and undetectable T4 levels at birth develop with normal intelligence, although as a population academic performance tends to be below that of siblings and mild learning problems occur in some.[1]
Congenital hypothyroidism is the most common preventable cause of mental retardation. Few treatments in the practice of medicine provide as large a benefit for as small an effort.