Hypoparathyroidism causes: Difference between revisions
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==Overview== | |||
==Causes== | |||
Hypoparathyroidism can have a number of divergent causes: | |||
* Removal of the parathyroid glands in [[thyroid]] surgery ([[thyroidectomy]]) is a recognised cause. It is now uncommon, as [[surgery|surgeon]]s generally spare them during the procedure after identifying them. | |||
* [[Autoimmune disorder|Autoimmune]] invasion and destruction is the most common non-surgical cause. It can occur as part of [[autoimmune polyendocrine syndrome]]s. | |||
* [[Hemochromatosis]] can lead to iron accumulation and consequent dysfunction of a number of endocrine organs, including the parathyroids. | |||
* Absence or dysfunction of the parathyroid glands is one of the components of [[Chromosome 22, microdeletion 22 q11|chromosome 22q11 microdeletion syndrome]] (other names: DiGeorge syndrome, Schprintzen syndrome, velocardiofacial syndrome). | |||
* [[Magnesium]] deficiency | |||
* Some very [[rare disease]]s | |||
* Idiopathic (of unknown cause), occasionally familial | |||
==References== | ==References== | ||
Revision as of 21:44, 20 September 2012
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Overview
Causes
Hypoparathyroidism can have a number of divergent causes:
- Removal of the parathyroid glands in thyroid surgery (thyroidectomy) is a recognised cause. It is now uncommon, as surgeons generally spare them during the procedure after identifying them.
- Autoimmune invasion and destruction is the most common non-surgical cause. It can occur as part of autoimmune polyendocrine syndromes.
- Hemochromatosis can lead to iron accumulation and consequent dysfunction of a number of endocrine organs, including the parathyroids.
- Absence or dysfunction of the parathyroid glands is one of the components of chromosome 22q11 microdeletion syndrome (other names: DiGeorge syndrome, Schprintzen syndrome, velocardiofacial syndrome).
- Magnesium deficiency
- Some very rare diseases
- Idiopathic (of unknown cause), occasionally familial