Thrombophilia overview: Difference between revisions
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'''Thrombophilia''' is defined as an increased risk of [[thrombosis]] in the body, due to an abnormality in the system of [[coagulation]]. Thrombophilia can be inherited or acquired. More than 50% of the cases of [[thrombosis]] are associated with an underlying thrombophilia. Thrombophilias are mostly associated with venous thromboembolism like [[deep vein thrombosis]] in lower extremities or [[pulmonary embolism]]. Relatively less is known about thrombophilias that predispose to arterial thromboembolism<ref name="pmid11309638">{{cite journal |author=Seligsohn U, Lubetsky A |title=Genetic susceptibility to venous thrombosis |journal=N. Engl. J. Med. |volume=344 |issue=16 |pages=1222–31 |year=2001 |month=April |pmid=11309638 |doi=10.1056/NEJM200104193441607 |url=}}</ref>. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} |
Revision as of 13:21, 21 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Thrombophilia is defined as an increased risk of thrombosis in the body, due to an abnormality in the system of coagulation. Thrombophilia can be inherited or acquired. More than 50% of the cases of thrombosis are associated with an underlying thrombophilia. Thrombophilias are mostly associated with venous thromboembolism like deep vein thrombosis in lower extremities or pulmonary embolism. Relatively less is known about thrombophilias that predispose to arterial thromboembolism[1].