Idiopathic thrombocytopenic purpura causes: Difference between revisions
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==Overview== | ==Overview== | ||
==Causes== | ==Causes== | ||
The cause of ITP is thought to be related to chronic infections such as [[HIV]], [[hepatitis C]] and [[H. Pylori]]. | The cause of ITP is thought to be related to chronic infections such as [[HIV]], [[hepatitis C]] and [[H. Pylori]]. | ||
*ITP occurs when certain '''immune system cells produce antibodies against platelets.''' Platelets help blood clot by clumping together to plug small holes in damaged blood vessels. | |||
*The antibodies attach to the platelets. The spleen destroys the platelets that carry the antibodies. | |||
*In children, the disease sometimes follows a viral infection. In adults, it is more often a chronic (long-term) disease and can occur after a viral infection, with use of certain drugs, during pregnancy, or as part of an immune disorder. | |||
*ITP affects women more frequently than men, and is more common in children than adults. The disease affects boys and girls equally. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
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[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category:Mature chapter]] | [[Category:Mature chapter]] | ||
Revision as of 15:33, 21 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Causes
The cause of ITP is thought to be related to chronic infections such as HIV, hepatitis C and H. Pylori.
- ITP occurs when certain immune system cells produce antibodies against platelets. Platelets help blood clot by clumping together to plug small holes in damaged blood vessels.
- The antibodies attach to the platelets. The spleen destroys the platelets that carry the antibodies.
- In children, the disease sometimes follows a viral infection. In adults, it is more often a chronic (long-term) disease and can occur after a viral infection, with use of certain drugs, during pregnancy, or as part of an immune disorder.
- ITP affects women more frequently than men, and is more common in children than adults. The disease affects boys and girls equally.