Asplenia natural history, complications and prognosis: Difference between revisions
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==Overview== | |||
==Natural History== | |||
==Complications== | |||
Asplenia increases the risk of [[septicaemia]] from encapsulated bacteria, and can result in a syndrome known as [[overwhelming post splenectomy infection]] (OPSI) which can kill within a few hours. In particular patients are at risk from [[Pneumococcus]], but also ''[[Haemophilus influenzae]]'' & [[Meningococcus]]. | |||
The risk to asplenic patients has been expressed as equivalent for a child to die in home accident, and for adults dying in a road traffic accident (reference UK Splenectomy Trust Advice) - so sensible precautions are needed, but no panic.<!-- | |||
--><ref>{{cite web | title=Splenectomy and Infection | url=http://www.ekpt.nhs.uk/pdf/PILs/EKHT_Leaflets/Splenectomy_and_Infection.pdf | format=PDF | date=March 2002 | publisher=Splenectomy Trust | accessdate=2006-12-12}} - reprint from Kent and Medway NHS and Social Care Partnership Trust</ref> | |||
==Prognosis== | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 15:20, 21 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Natural History
Complications
Asplenia increases the risk of septicaemia from encapsulated bacteria, and can result in a syndrome known as overwhelming post splenectomy infection (OPSI) which can kill within a few hours. In particular patients are at risk from Pneumococcus, but also Haemophilus influenzae & Meningococcus.
The risk to asplenic patients has been expressed as equivalent for a child to die in home accident, and for adults dying in a road traffic accident (reference UK Splenectomy Trust Advice) - so sensible precautions are needed, but no panic.[1]
Prognosis
References
- ↑ "Splenectomy and Infection" (PDF). Splenectomy Trust. March 2002. Retrieved 2006-12-12. - reprint from Kent and Medway NHS and Social Care Partnership Trust