Idiopathic thrombocytopenic purpura history and symptoms: Difference between revisions
No edit summary |
|||
| Line 2: | Line 2: | ||
{{ITP}} | {{ITP}} | ||
{{CMG}} | {{CMG}} | ||
==History and Symptoms== | ==History and Symptoms== | ||
ITP is usually chronic in adults<ref name="pmid11919310">{{cite journal |author=Cines DB, Blanchette VS |title=Immune thrombocytopenic purpura |journal=N. Engl. J. Med. |volume=346 |issue=13 |pages=995-1008 |year=2002 |pmid=11919310 |doi=10.1056/NEJMra010501}}</ref> and the probability of durable remission is 20–40%.<ref name="pmid17122451">{{cite journal |author=Stevens W, Koene H, Zwaginga JJ, Vreugdenhil G |title=Chronic idiopathic thrombocytopenic purpura: present strategy, guidelines and new insights |journal=The Netherlands journal of medicine |volume=64 |issue=10 |pages=356-63 |year=2006 |pmid=17122451 |doi=}}</ref> Usually, ITP patients suffer from [[bruising]]; [[petechia]]e, [[nosebleed]]s and bleeding [[gums]] may occur if the platelet count is below 20,000,<ref name="pmid15660520">{{cite journal |author=Cines DB, McMillan R |title=Management of adult idiopathic thrombocytopenic purpura |journal=Annu. Rev. Med. |volume=56 |issue= |pages=425-42 |year=2005 |pmid=15660520 |doi=10.1146/annurev.med.56.082103.104644}}</ref> compared to a normal range of 150,000–400,000 per mm<sup>3</sup>. | ITP is usually chronic in adults<ref name="pmid11919310">{{cite journal |author=Cines DB, Blanchette VS |title=Immune thrombocytopenic purpura |journal=N. Engl. J. Med. |volume=346 |issue=13 |pages=995-1008 |year=2002 |pmid=11919310 |doi=10.1056/NEJMra010501}}</ref> and the probability of durable remission is 20–40%.<ref name="pmid17122451">{{cite journal |author=Stevens W, Koene H, Zwaginga JJ, Vreugdenhil G |title=Chronic idiopathic thrombocytopenic purpura: present strategy, guidelines and new insights |journal=The Netherlands journal of medicine |volume=64 |issue=10 |pages=356-63 |year=2006 |pmid=17122451 |doi=}}</ref> Usually, ITP patients suffer from [[bruising]]; [[petechia]]e, [[nosebleed]]s and bleeding [[gums]] may occur if the platelet count is below 20,000,<ref name="pmid15660520">{{cite journal |author=Cines DB, McMillan R |title=Management of adult idiopathic thrombocytopenic purpura |journal=Annu. Rev. Med. |volume=56 |issue= |pages=425-42 |year=2005 |pmid=15660520 |doi=10.1146/annurev.med.56.082103.104644}}</ref> compared to a normal range of 150,000–400,000 per mm<sup>3</sup>. | ||
| Line 23: | Line 22: | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category: | [[Category:Needs overview]] | ||
Revision as of 15:20, 4 March 2013
|
Idiopathic thrombocytopenic purpura Microchapters |
|
Differentiating Idiopathic thrombocytopenic purpura from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Idiopathic thrombocytopenic purpura history and symptoms On the Web |
|
American Roentgen Ray Society Images of Idiopathic thrombocytopenic purpura history and symptoms |
|
FDA on Idiopathic thrombocytopenic purpura history and symptoms |
|
CDC on Idiopathic thrombocytopenic purpura history and symptoms |
|
Idiopathic thrombocytopenic purpura history and symptoms in the news |
|
Blogs on Idiopathic thrombocytopenic purpura history and symptoms |
|
Directions to Hospitals Treating Idiopathic thrombocytopenic purpura |
|
Risk calculators and risk factors for Idiopathic thrombocytopenic purpura history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
History and Symptoms
ITP is usually chronic in adults[1] and the probability of durable remission is 20–40%.[2] Usually, ITP patients suffer from bruising; petechiae, nosebleeds and bleeding gums may occur if the platelet count is below 20,000,[3] compared to a normal range of 150,000–400,000 per mm3.
Evan's syndrome can occur in ~1% of cases and is manifest by an autoimmune (Coombs +)hemolytic anemia with ITP.
Symptoms include:
- Abnormally heavy menstruation
- Bleeding into the skin causes a characteristic skin rash that looks like pinpoint red spots (petechial rash)
- Easy bruising
- Nosebleed or bleeding in the mouth
References
- ↑ Cines DB, Blanchette VS (2002). "Immune thrombocytopenic purpura". N. Engl. J. Med. 346 (13): 995–1008. doi:10.1056/NEJMra010501. PMID 11919310.
- ↑ Stevens W, Koene H, Zwaginga JJ, Vreugdenhil G (2006). "Chronic idiopathic thrombocytopenic purpura: present strategy, guidelines and new insights". The Netherlands journal of medicine. 64 (10): 356–63. PMID 17122451.
- ↑ Cines DB, McMillan R (2005). "Management of adult idiopathic thrombocytopenic purpura". Annu. Rev. Med. 56: 425–42. doi:10.1146/annurev.med.56.082103.104644. PMID 15660520.