Multi-drug-resistant tuberculosis differential diagnosis: Difference between revisions
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{{Multi-drug | {{Multi-drug resistant tuberculosis}} | ||
{{CMG}}; {{AE}} {{AL}} | |||
==Overview== | |||
Pulmonary tuberculosis must be differentiated from other diseases that cause [[cough]], [[fever]], [[night sweats]], [[hemoptysis]] and [[weight loss]], such as: [[brucellosis]], [[bronchogenic carcinoma]], [[Hodgkin lymphoma]], [[bacterial pneumonia]], [[sarcoidosis]], [[mycoplasmal pneumonia]]. | |||
==Differential Diagnosis== | |||
===Pulmonary Tuberculosis=== | |||
{| style="border: 0px; font-size: 90%; margin: 3px; width: 700px;" align=center | |||
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! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Disease}} | |||
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Findings}} | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[Bacterial pneumonia]] | |||
| style="padding: 5px 5px; background: #F5F5F5;" | Sudden onset of symptoms, such as high [[fever]], [[cough]], purulent [[sputum]], [[chest pain]]. Consolidation on chest X-ray, [[leukocytosis]]. | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |[[Bronchogenic carcinoma]] | |||
| style="padding: 5px 5px; background: #F5F5F5;" | Can be asymptomatic, usually at older ages (> 50 years old), [[cough]], [[hemoptysis]], [[weight loss]] | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |[[Brucellosis]] | |||
| style="padding: 5px 5px; background: #F5F5F5;" | [[Fever]], [[anorexia]], [[night sweats]], [[malaise]],[[back pain]] , [[headache]], and [[depression]]. History of exposure to infected animal | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |[[Hodgkin lymphoma]] | |||
| style="padding: 5px 5px; background: #F5F5F5;" | [[Fever]], [[night sweats]], [[pruritus]], painless [[adenopathy]], [[mediastinal mass]] | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |[[Mycoplasmal pneumonia]] | |||
| style="padding: 5px 5px; background: #F5F5F5;" | Gradual onset of [[dry cough]], [[headache]], [[malaise]], [[sore throat]]. Diffuse bilateral infiltrates in chest X-ray. | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |[[Sarcoidosis]] | |||
| style="padding: 5px 5px; background: #F5F5F5;" |Non-caseating granulomas in lungs and other organs, bilateral hiliar adenopathy, predominantly in African American females. | |||
|- | |||
| style="padding: 5px 5px; background: #F5F5F5;" colspan="2"|<small>Adapted from Mandell, Douglas, and Bennett's principles and practice of infectious diseases 2010 <ref>{{cite book | last = Mandell | first = Gerald | title = Mandell, Douglas, and Bennett's principles and practice of infectious diseases | publisher = Churchill Livingstone/Elsevier | location = Philadelphia, PA | year = 2010 | isbn = 0443068399 }}</ref> </small> | |||
|} | |||
===Extra-Pulmonary Tuberculosis=== | |||
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! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Extra-Pulmonary Location}} | |||
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Differential Diagnosis}} | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |Tuberculous Lymphadenitis | |||
| style="padding: 5px 5px; background: #F5F5F5;" | [[Lymphoma]], [[squamous cell carcinoma]], [[papillary thyroid cancer]], [[pyogenic infection]] | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |Skeletal Tuberculosis | |||
| style="padding: 5px 5px; background: #F5F5F5;" | [[Multiple myeloma]], bone [[metastasis]], [[spinal cord abscess]], [[osteoporosis]] | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | Tuberculous Arthrits | |||
| style="padding: 5px 5px; background: #F5F5F5;" | Bacterial [[septic arthritis]], [[pseudogout]] | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |Central Nervous System Tuberculosis | |||
| style="padding: 5px 5px; background: #F5F5F5;" | [[Bacterial meningitis]], [[viral meningitis]], [[encephalitis]] | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |Tuberculosis Peritonitis | |||
| style="padding: 5px 5px; background: #F5F5F5;" |[[Bacterial peritonitis]], chronic [[peritoneal dialysis]] | |||
|- | |||
| style="padding: 5px 5px; background: #F5F5F5;" colspan="2"|<small>Adapted from Asian Spine J. Feb 2014; 8(1): 97–111<ref name="Moon2014">{{cite journal|last1=Moon|first1=Myung-Sang|title=Tuberculosis of Spine: Current Views in Diagnosis and Management|journal=Asian Spine Journal|volume=8|issue=1|year=2014|pages=97|issn=1976-1902|doi=10.4184/asj.2014.8.1.97}}</ref>; Handbook of Clinical Neurology<ref name="Garcia-Monco2014">{{cite journal|last1=Garcia-Monco|first1=Juan Carlos|title=Tuberculosis|volume=121|year=2014|pages=1485–1499|issn=00729752|doi=10.1016/B978-0-7020-4088-7.00100-0}}</ref>; Circulation Dec 2005 vol.112 no.23 3608-3616<ref name="Mayosi2005">{{cite journal|last1=Mayosi|first1=B. M.|title=Tuberculous Pericarditis|journal=Circulation|volume=112|issue=23|year=2005|pages=3608–3616|issn=0009-7322|doi=10.1161/CIRCULATIONAHA.105.543066}}</ref>; Am J Trop Med Hyg 2013 vol. 88 no. 1 54-64<ref name="Daherda Silva Junior2013">{{cite journal|last1=Daher|first1=E. D. F.|last2=da Silva Junior|first2=G. B.|last3=Barros|first3=E. J. G.|title=Renal Tuberculosis in the Modern Era|journal=American Journal of Tropical Medicine and Hygiene|volume=88|issue=1|year=2013|pages=54–64|issn=0002-9637|doi=10.4269/ajtmh.2013.12-0413}}</ref> Clin Infect Dis.(2011)53(6):555-562.<ref name="FontanillaBarnes2011">{{cite journal|last1=Fontanilla|first1=J.-M.|last2=Barnes|first2=A.|last3=von Reyn|first3=C. F.|title=Current Diagnosis and Management of Peripheral Tuberculous Lymphadenitis|journal=Clinical Infectious Diseases|volume=53|issue=6|year=2011|pages=555–562|issn=1058-4838|doi=10.1093/cid/cir454}}</ref> </small> | |||
|} | |||
==References== | ==References== | ||
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[[Category:Bacterial diseases]] | |||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category: | [[Category:Infectious disease]] | ||
[[Category:Pulmonology]] | [[Category:Pulmonology]] | ||
[[Category: | [[Category:Needs content]] | ||
[[Category: | [[Category:Primary care]] | ||
Revision as of 13:25, 26 September 2014
Template:Multi-drug resistant tuberculosis Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]
Overview
Pulmonary tuberculosis must be differentiated from other diseases that cause cough, fever, night sweats, hemoptysis and weight loss, such as: brucellosis, bronchogenic carcinoma, Hodgkin lymphoma, bacterial pneumonia, sarcoidosis, mycoplasmal pneumonia.
Differential Diagnosis
Pulmonary Tuberculosis
| Disease | Findings |
|---|---|
| Bacterial pneumonia | Sudden onset of symptoms, such as high fever, cough, purulent sputum, chest pain. Consolidation on chest X-ray, leukocytosis. |
| Bronchogenic carcinoma | Can be asymptomatic, usually at older ages (> 50 years old), cough, hemoptysis, weight loss |
| Brucellosis | Fever, anorexia, night sweats, malaise,back pain , headache, and depression. History of exposure to infected animal |
| Hodgkin lymphoma | Fever, night sweats, pruritus, painless adenopathy, mediastinal mass |
| Mycoplasmal pneumonia | Gradual onset of dry cough, headache, malaise, sore throat. Diffuse bilateral infiltrates in chest X-ray. |
| Sarcoidosis | Non-caseating granulomas in lungs and other organs, bilateral hiliar adenopathy, predominantly in African American females. |
| Adapted from Mandell, Douglas, and Bennett's principles and practice of infectious diseases 2010 [1] | |
Extra-Pulmonary Tuberculosis
| Extra-Pulmonary Location | Differential Diagnosis |
|---|---|
| Tuberculous Lymphadenitis | Lymphoma, squamous cell carcinoma, papillary thyroid cancer, pyogenic infection |
| Skeletal Tuberculosis | Multiple myeloma, bone metastasis, spinal cord abscess, osteoporosis |
| Tuberculous Arthrits | Bacterial septic arthritis, pseudogout |
| Central Nervous System Tuberculosis | Bacterial meningitis, viral meningitis, encephalitis |
| Tuberculosis Peritonitis | Bacterial peritonitis, chronic peritoneal dialysis |
| Adapted from Asian Spine J. Feb 2014; 8(1): 97–111[2]; Handbook of Clinical Neurology[3]; Circulation Dec 2005 vol.112 no.23 3608-3616[4]; Am J Trop Med Hyg 2013 vol. 88 no. 1 54-64[5] Clin Infect Dis.(2011)53(6):555-562.[6] | |
References
- ↑ Mandell, Gerald (2010). Mandell, Douglas, and Bennett's principles and practice of infectious diseases. Philadelphia, PA: Churchill Livingstone/Elsevier. ISBN 0443068399.
- ↑ Moon, Myung-Sang (2014). "Tuberculosis of Spine: Current Views in Diagnosis and Management". Asian Spine Journal. 8 (1): 97. doi:10.4184/asj.2014.8.1.97. ISSN 1976-1902.
- ↑ Garcia-Monco, Juan Carlos (2014). "Tuberculosis". 121: 1485–1499. doi:10.1016/B978-0-7020-4088-7.00100-0. ISSN 0072-9752.
- ↑ Mayosi, B. M. (2005). "Tuberculous Pericarditis". Circulation. 112 (23): 3608–3616. doi:10.1161/CIRCULATIONAHA.105.543066. ISSN 0009-7322.
- ↑ Daher, E. D. F.; da Silva Junior, G. B.; Barros, E. J. G. (2013). "Renal Tuberculosis in the Modern Era". American Journal of Tropical Medicine and Hygiene. 88 (1): 54–64. doi:10.4269/ajtmh.2013.12-0413. ISSN 0002-9637.
- ↑ Fontanilla, J.-M.; Barnes, A.; von Reyn, C. F. (2011). "Current Diagnosis and Management of Peripheral Tuberculous Lymphadenitis". Clinical Infectious Diseases. 53 (6): 555–562. doi:10.1093/cid/cir454. ISSN 1058-4838.