Actinomycosis natural history: Difference between revisions
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==Overview== | ==Overview== | ||
Once in the tissue, it forms an [[abscess]], producing a hard, red to reddish-purple lump, often on the jaw, from which comes the condition's common name, "lumpy jaw." Eventually, the abscess breaks through the skin surface to produce a draining sinus tract. With treatment, it is completely treatable. | Once in the tissue, it forms an [[abscess]], producing a hard, red to reddish-purple lump, often on the jaw, from which comes the condition's common name, "lumpy jaw." Eventually, the abscess breaks through the skin surface to produce a draining sinus tract. With treatment, it is completely treatable. | ||
==Natural History== | |||
If left untreated, patients with Actinomycosis may progress to develop focal organ involvement with mass-like features and dvelopment of sinus tracts (which can heal and re-form) | |||
==Prognosis== | |||
*The prognosis is generally excellent with prompt and effective antimicrobial treatment in patients with uncomplicated actinomycosis that does not affect the CNS. | |||
*The factors that define the outcomes of the diesease include | |||
**Site of infection: the highest mortality is seen if the disease involves central nervous system. | |||
**The time to diagnosis: delayed presentation results in poorer outcomes | |||
**The time to the start of appropriate treatment. | |||
*Mortality range from 0% to 28%.( hightest being in CNS) | |||
==Complications== | |||
Complications that can develop as a result of actinomycosis are | |||
*Extension of disease can result in osteomyelitis of the mandible, ribs, or vertebrae. | |||
*Endocarditis | |||
*Pericarditis | |||
*CNS disease, including brain abscess; chronic meningitis | |||
==Possible Complications== | ==Possible Complications== |
Revision as of 12:25, 21 March 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Once in the tissue, it forms an abscess, producing a hard, red to reddish-purple lump, often on the jaw, from which comes the condition's common name, "lumpy jaw." Eventually, the abscess breaks through the skin surface to produce a draining sinus tract. With treatment, it is completely treatable.
Natural History
If left untreated, patients with Actinomycosis may progress to develop focal organ involvement with mass-like features and dvelopment of sinus tracts (which can heal and re-form)
Prognosis
- The prognosis is generally excellent with prompt and effective antimicrobial treatment in patients with uncomplicated actinomycosis that does not affect the CNS.
- The factors that define the outcomes of the diesease include
- Site of infection: the highest mortality is seen if the disease involves central nervous system.
- The time to diagnosis: delayed presentation results in poorer outcomes
- The time to the start of appropriate treatment.
- Mortality range from 0% to 28%.( hightest being in CNS)
Complications
Complications that can develop as a result of actinomycosis are
- Extension of disease can result in osteomyelitis of the mandible, ribs, or vertebrae.
- Endocarditis
- Pericarditis
- CNS disease, including brain abscess; chronic meningitis
Possible Complications
Meningitis can rarely develop from this infection.
References
de:Aktinomykose gl:Actinomicose hr:Aktinomikoza nl:Actinomycose sr:Актиномикоза fi:Aktinomykoosi uk:Актиномікоз