Tonsillitis pathophysiology: Difference between revisions
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== | ==Overview== | ||
==Pathophysiology== | ==Pathophysiology== | ||
Under normal circumstances, as viruses and bacteria enter the body through the nose and mouth, they are filtered in the [[tonsil]]s.<ref name="Kempen"/><ref name="Perry"/> Within the tonsils, [[white blood cell]]s of the immune system mount an attack that helps destroy the viruses or bacteria by producing inflammatory cytokines like [[Phospholipase A2]], <ref> {{cite journal | title = Circulating phospholipase-A2 activity in obstructive sleep apnea | journal = International Journal of Pediatric Otorhinolaryngology | date = 2012 | id = PMID 22297210 | doi = 10.1016/j.ijporl.2011.12.026 | accessdate = 2012-08-28}}</ref> which also lead to fever.<ref name="Kempen">{{cite journal |author=van Kempen MJ, Rijkers GT, Van Cauwenberge PB |title=The immune response in adenoids and tonsils |journal=Int. Arch. Allergy Immunol. |volume=122 |issue=1 |pages=8–19 |year=2000 |month=May |pmid=10859465 |doi= 10.1159/000024354}}</ref><ref name="Perry">{{cite journal |author=Perry M, Whyte A |title=Immunology of the tonsils |journal=Immunology Today |volume=19 |issue=9 |pages=414–21 |year=1998 |month=September |pmid=9745205 |doi= 10.1016/S0167-5699(98)01307-3}}</ref> | Under normal circumstances, as viruses and bacteria enter the body through the nose and mouth, they are filtered in the [[tonsil]]s.<ref name="Kempen"/><ref name="Perry"/> Within the tonsils, [[white blood cell]]s of the immune system mount an attack that helps destroy the viruses or bacteria by producing inflammatory cytokines like [[Phospholipase A2]], <ref> {{cite journal | title = Circulating phospholipase-A2 activity in obstructive sleep apnea | journal = International Journal of Pediatric Otorhinolaryngology | date = 2012 | id = PMID 22297210 | doi = 10.1016/j.ijporl.2011.12.026 | accessdate = 2012-08-28}}</ref> which also lead to fever.<ref name="Kempen">{{cite journal |author=van Kempen MJ, Rijkers GT, Van Cauwenberge PB |title=The immune response in adenoids and tonsils |journal=Int. Arch. Allergy Immunol. |volume=122 |issue=1 |pages=8–19 |year=2000 |month=May |pmid=10859465 |doi= 10.1159/000024354}}</ref><ref name="Perry">{{cite journal |author=Perry M, Whyte A |title=Immunology of the tonsils |journal=Immunology Today |volume=19 |issue=9 |pages=414–21 |year=1998 |month=September |pmid=9745205 |doi= 10.1016/S0167-5699(98)01307-3}}</ref> | ||
==References== | |||
{{Reflist|2}} | {{Reflist|2}} | ||
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Overview
Pathophysiology
Under normal circumstances, as viruses and bacteria enter the body through the nose and mouth, they are filtered in the tonsils.[1][2] Within the tonsils, white blood cells of the immune system mount an attack that helps destroy the viruses or bacteria by producing inflammatory cytokines like Phospholipase A2, [3] which also lead to fever.[1][2]
References
- ↑ 1.0 1.1 van Kempen MJ, Rijkers GT, Van Cauwenberge PB (2000). "The immune response in adenoids and tonsils". Int. Arch. Allergy Immunol. 122 (1): 8–19. doi:10.1159/000024354. PMID 10859465. Unknown parameter
|month=ignored (help) - ↑ 2.0 2.1 Perry M, Whyte A (1998). "Immunology of the tonsils". Immunology Today. 19 (9): 414–21. doi:10.1016/S0167-5699(98)01307-3. PMID 9745205. Unknown parameter
|month=ignored (help) - ↑ "Circulating phospholipase-A2 activity in obstructive sleep apnea". International Journal of Pediatric Otorhinolaryngology. 2012. doi:10.1016/j.ijporl.2011.12.026. PMID 22297210.
|access-date=requires|url=(help)