Acute tubular necrosis causes: Difference between revisions
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==Overview== | ==Overview== | ||
==Causes== | ==Causes== | ||
==Toxic Acute Tubular Necrosis == | ===Toxic Acute Tubular Necrosis === | ||
Toxic ATN can be caused by free [[hemoglobin]] or [[myoglobin]], by medication such as [[antibiotic]]s and cytostatic drugs, or by intoxication ([[ethylene glycol]], "anti-freeze"). | Toxic ATN can be caused by free [[hemoglobin]] or [[myoglobin]], by medication such as [[antibiotic]]s and cytostatic drugs, or by intoxication ([[ethylene glycol]], "anti-freeze"). | ||
==Ischemic Acute Tubular Necrosis== | ===Ischemic Acute Tubular Necrosis=== | ||
Ischemic Acute Tubular Necrosis can be caused when the [[kidneys]] are not sufficiently perfused for a long period of time (i.e. [[renal artery stenosis]]) or during [[Shock (medical)|shock]]. [[Hypoperfusion]] can also be caused by [[embolism]] of the renal arteries. | Ischemic Acute Tubular Necrosis can be caused when the [[kidneys]] are not sufficiently perfused for a long period of time (i.e. [[renal artery stenosis]]) or during [[Shock (medical)|shock]]. [[Hypoperfusion]] can also be caused by [[embolism]] of the renal arteries. | ||
Ischemic Acute Tubular Necrosis specifically causes ''skip lesions'' through the tubules. | Ischemic Acute Tubular Necrosis specifically causes ''skip lesions'' through the tubules. | ||
Revision as of 01:46, 1 October 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]
Overview
Causes
Toxic Acute Tubular Necrosis
Toxic ATN can be caused by free hemoglobin or myoglobin, by medication such as antibiotics and cytostatic drugs, or by intoxication (ethylene glycol, "anti-freeze").
Ischemic Acute Tubular Necrosis
Ischemic Acute Tubular Necrosis can be caused when the kidneys are not sufficiently perfused for a long period of time (i.e. renal artery stenosis) or during shock. Hypoperfusion can also be caused by embolism of the renal arteries. Ischemic Acute Tubular Necrosis specifically causes skip lesions through the tubules.