Diphtheria pathophysiology

Diphtheria Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Mechanism

Diphtheria toxin catalyzes the ADP-ribosylation of, and inactivates, the elongation factor eEF-2. In this way, it acts to inhibit translation during eukaryotic protein synthesis.

References

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