Zygomycosis surgery: Difference between revisions
Rim Halaby (talk | contribs) No edit summary |
Rim Halaby (talk | contribs) No edit summary |
||
| Line 2: | Line 2: | ||
{{Zygomycosis}} | {{Zygomycosis}} | ||
{{CMG}} | {{CMG}} | ||
==Overview== | ==Overview== | ||
==Surgery== | ==Surgery== | ||
Surgical therapy can be very drastic, and in some cases of Rhinocerebral disease removal of infected brain tissue may be required. In some cases surgery may be disfiguring because it may involve removal of the [[palate]], [[nasal cavity]], or [[Eye#Three_layers|eye structure]]s. | Surgical therapy can be very drastic, and in some cases of Rhinocerebral disease removal of infected brain tissue may be required. In some cases surgery may be disfiguring because it may involve removal of the [[palate]], [[nasal cavity]], or [[Eye#Three_layers|eye structure]]s. Surgery may be extended to more than one operation. It has been hypothesised that [[hyperbaric]] [[oxygen]] may be beneficial as an adjunctive therapy because higher oxygen [[pressure]] increases the ability of [[Neutrophil granulocyte|neutrophils]] to kill the organism. | ||
Treatment for Phycomycosis is very difficult and includes [[surgery]] when possible. Postoperative recurrence is common. [[Antifungal drug]]s show only limited effect on the disease, but [[itraconazole]] and [[terbinafine|terbinafine hydrochloride]] are often used for two to three months following surgery. | Treatment for Phycomycosis is very difficult and includes [[surgery]] when possible. Postoperative recurrence is common. [[Antifungal drug]]s show only limited effect on the disease, but [[itraconazole]] and [[terbinafine|terbinafine hydrochloride]] are often used for two to three months following surgery. Humans with ''Basidiobolus'' infections have been treated with [[amphotericin B]] and [[potassium iodide]]. For pythiosis and lagenidiosis, a new drug targeting water moulds called [[caspofungin]] is available, but it is very expensive. [[Immunotherapy]] has been used successfully in humans and horses with pythiosis. | ||
==References== | ==References== | ||
Revision as of 20:34, 3 October 2012
|
Zygomycosis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Zygomycosis surgery On the Web |
|
American Roentgen Ray Society Images of Zygomycosis surgery |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Surgery
Surgical therapy can be very drastic, and in some cases of Rhinocerebral disease removal of infected brain tissue may be required. In some cases surgery may be disfiguring because it may involve removal of the palate, nasal cavity, or eye structures. Surgery may be extended to more than one operation. It has been hypothesised that hyperbaric oxygen may be beneficial as an adjunctive therapy because higher oxygen pressure increases the ability of neutrophils to kill the organism.
Treatment for Phycomycosis is very difficult and includes surgery when possible. Postoperative recurrence is common. Antifungal drugs show only limited effect on the disease, but itraconazole and terbinafine hydrochloride are often used for two to three months following surgery. Humans with Basidiobolus infections have been treated with amphotericin B and potassium iodide. For pythiosis and lagenidiosis, a new drug targeting water moulds called caspofungin is available, but it is very expensive. Immunotherapy has been used successfully in humans and horses with pythiosis.
References