Tetralogy of fallot epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, M.B.B.S. [2], Keri Shafer, M.D. [3]; Assistant Editor-In-Chief: Kristin Feeney, B.S. [4]

Overview

Tetralogy of Fallot represents 5-7% of congenital heart defects. Tetralogy of Fallot is the most common cause of cyanotic heart disease and accounts for one third of all cases of cyanotic heart disease.

Epidemiology and Demographics

• Tetralogy of Fallot occurs in approximately 3 to 6 per 10,000 births
• It represents 5-7% of congenital heart defects.

Genetics

• The majority of cases are thought to be sporadic and are not familial.
• The incidence in siblings is 1% to 5%.

Gender

• Tetralogy of Fallot occurs slightly more often in males than in females.

References

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