Schistosomiasis natural history, complications and prognosis: Difference between revisions
Hardik Patel (talk | contribs) No edit summary |
Hardik Patel (talk | contribs) |
||
| Line 6: | Line 6: | ||
==Overview== | ==Overview== | ||
==Complications== | ==Natural History and Complications== | ||
Above all, schistosomiasis is a [[chronic disease]]. Pathology of ''S. mansoni'' and ''S. japonicum'' schistosomiasis includes: [[Katayama fever]], hepatic perisinusoidal egg [[granulomas]], Symmers’ pipe stem periportal fibrosis, [[portal hypertension]], and occasional [[embolism|embolic]] egg granulomas in [[brain]] or [[spinal cord]]. Pathology of ''S. haematobium'' schistosomiasis includes: [[hematuria]], [[scar]]ring, [[calcification]], [[squamous cell carcinoma]], and occasional embolic egg granulomas in brain or spinal cord. [[Bladder cancer]] diagnosis and mortality are generally elevated in affected areas. | Above all, schistosomiasis is a [[chronic disease]]. Pathology of ''S. mansoni'' and ''S. japonicum'' schistosomiasis includes: [[Katayama fever]], hepatic perisinusoidal egg [[granulomas]], Symmers’ pipe stem periportal fibrosis, [[portal hypertension]], and occasional [[embolism|embolic]] egg granulomas in [[brain]] or [[spinal cord]]. Pathology of ''S. haematobium'' schistosomiasis includes: [[hematuria]], [[scar]]ring, [[calcification]], [[squamous cell carcinoma]], and occasional embolic egg granulomas in brain or spinal cord. [[Bladder cancer]] diagnosis and mortality are generally elevated in affected areas. | ||
Occasionally [[central nervous system]] lesions occur: cerebral granulomatous disease may be caused by ectopic ''S. japonicum'' eggs in the [[brain]], and granulomatous lesions around ectopic eggs in the [[spinal cord]] from ''S. mansoni'' and ''S. haematobium'' infections may result in a transverse [[myelitis]] with flaccid [[paraplegia]]. Continuing infection may cause granulomatous reactions and [[fibrosis]] in the affected organs, which may result in manifestations that include: | |||
* Colonic [[polyposis]] with bloody diarrhea (''Schistosoma mansoni'' mostly); | |||
* [[Portal hypertension]] with [[hematemesis]] and [[splenomegaly]] (''S. mansoni'', ''S. japonicum''); | |||
* [[Cystitis]] and ureteritis (''S. haematobium'') with [[hematuria]], which can progress to [[bladder cancer]]; | |||
* [[Pulmonary hypertension]] (''S. mansoni'', ''S. japonicum'', more rarely ''S. haematobium''); | |||
* [[Glomerulonephritis]]; and central nervous system lesions. | |||
==References== | ==References== | ||
Revision as of 13:11, 11 October 2012
|
Schistosomiasis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Schistosomiasis natural history, complications and prognosis On the Web |
|
American Roentgen Ray Society Images of Schistosomiasis natural history, complications and prognosis |
|
FDA on Schistosomiasis natural history, complications and prognosis |
|
CDC on Schistosomiasis natural history, complications and prognosis |
|
Schistosomiasis natural history, complications and prognosis in the news |
|
Blogs on Schistosomiasis natural history, complications and prognosis |
|
Risk calculators and risk factors for Schistosomiasis natural history, complications and prognosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing.
Overview
Natural History and Complications
Above all, schistosomiasis is a chronic disease. Pathology of S. mansoni and S. japonicum schistosomiasis includes: Katayama fever, hepatic perisinusoidal egg granulomas, Symmers’ pipe stem periportal fibrosis, portal hypertension, and occasional embolic egg granulomas in brain or spinal cord. Pathology of S. haematobium schistosomiasis includes: hematuria, scarring, calcification, squamous cell carcinoma, and occasional embolic egg granulomas in brain or spinal cord. Bladder cancer diagnosis and mortality are generally elevated in affected areas.
Occasionally central nervous system lesions occur: cerebral granulomatous disease may be caused by ectopic S. japonicum eggs in the brain, and granulomatous lesions around ectopic eggs in the spinal cord from S. mansoni and S. haematobium infections may result in a transverse myelitis with flaccid paraplegia. Continuing infection may cause granulomatous reactions and fibrosis in the affected organs, which may result in manifestations that include:
- Colonic polyposis with bloody diarrhea (Schistosoma mansoni mostly);
- Portal hypertension with hematemesis and splenomegaly (S. mansoni, S. japonicum);
- Cystitis and ureteritis (S. haematobium) with hematuria, which can progress to bladder cancer;
- Pulmonary hypertension (S. mansoni, S. japonicum, more rarely S. haematobium);
- Glomerulonephritis; and central nervous system lesions.