Brugada syndrome differential diagnosis: Difference between revisions
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* [[Hypercalcemia]] | * [[Hypercalcemia]] | ||
* [[Hyperkalemia]] | * [[Hyperkalemia]] | ||
* [[Hypothermia]], | * [[Hypothermia]], can cause an [[Osborn wave]] on the ECG which can sometimes resemble Brugada syndrome | ||
* [[Left ventricular hypertrophy]] | * [[Left ventricular hypertrophy]] | ||
* [[Pectus excavatum]] | |||
* [[Prinzmetal's angina]]<ref name="pmid14645641">{{cite journal |author=Wang K, Asinger RW, Marriott HJ |title=ST-segment elevation in conditions other than acute myocardial infarction |journal=[[The New England Journal of Medicine]] |volume=349 |issue=22 |pages=2128–35 |year=2003 |month=November |pmid=14645641 |doi=10.1056/NEJMra022580 |url=http://www.nejm.org/doi/abs/10.1056/NEJMra022580?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed |issn= |accessdate=2012-10-13}}</ref> | * [[Prinzmetal's angina]]<ref name="pmid14645641">{{cite journal |author=Wang K, Asinger RW, Marriott HJ |title=ST-segment elevation in conditions other than acute myocardial infarction |journal=[[The New England Journal of Medicine]] |volume=349 |issue=22 |pages=2128–35 |year=2003 |month=November |pmid=14645641 |doi=10.1056/NEJMra022580 |url=http://www.nejm.org/doi/abs/10.1056/NEJMra022580?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed |issn= |accessdate=2012-10-13}}</ref> | ||
* [[Right ventricular outflow tract obstruction|Mediastinal tumor compressing the right ventricular outflow tract]] ([[RVOT]]) | * [[Right ventricular outflow tract obstruction|Mediastinal tumor compressing the right ventricular outflow tract]] ([[RVOT]]) | ||
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* [[Right ventricular infarction]] | * [[Right ventricular infarction]] | ||
* [[Right ventricular ischemia]] | * [[Right ventricular ischemia]] | ||
* [[Right ventricular outflow tract]] compression due to a [[mediastinal tumor]] or [[hemopericardium]] | |||
* [[Thiamine deficiency]]<ref name="pmid7197132">{{cite journal |author=Read DH, Harrington DD |title=Experimentally induced thiamine deficiency in beagle dogs: clinical observations |journal=[[American Journal of Veterinary Research]] |volume=42 |issue=6 |pages=984–91 |year=1981 |month=June |pmid=7197132 |doi= |url= |issn= |accessdate=2012-10-13}}</ref> | * [[Thiamine deficiency]]<ref name="pmid7197132">{{cite journal |author=Read DH, Harrington DD |title=Experimentally induced thiamine deficiency in beagle dogs: clinical observations |journal=[[American Journal of Veterinary Research]] |volume=42 |issue=6 |pages=984–91 |year=1981 |month=June |pmid=7197132 |doi= |url= |issn= |accessdate=2012-10-13}}</ref> | ||
* Various central and autonomic nervous system abnormalities | * Various central and autonomic nervous system abnormalities | ||
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* Other normal variants (particularly in males) | * Other normal variants (particularly in males) | ||
Of note, a Brugada-like ECG can occasionally appear for a brief period or for a period of several hours after direct-current cardioversion; it is not known whether these patients are gene carriers for Brugada syndrome. | Of note, a Brugada-like ECG can occasionally appear for a brief period or for a period of several hours after direct-current cardioversion; it is not known whether these patients are gene carriers for Brugada syndrome. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Abnormalities that can lead to ST-segment elevation in the right precordial leads include the following:[1]
- Acute myocardial ischemia or infarction
- Acute myocarditis
- Acute pericarditis
- Acute pulmonary thromboemboli
- Arrhythmogenic right ventricular dysplasia / cardiomyopathy (ARVD/C)
- Cocaine intoxication
- Coronary spasm
- Dissecting aortic aneurysm[2]
- Duchenne muscular dystrophy[3]
- Early repolarization
- Friedreich ataxia
- Heterocyclic antidepressant overdose
- Hypercalcemia
- Hyperkalemia
- Hypothermia, can cause an Osborn wave on the ECG which can sometimes resemble Brugada syndrome
- Left ventricular hypertrophy
- Pectus excavatum
- Prinzmetal's angina[4]
- Mediastinal tumor compressing the right ventricular outflow tract (RVOT)
- Right (atypical) or left bundle-branch block
- Right ventricular infarction
- Right ventricular ischemia
- Right ventricular outflow tract compression due to a mediastinal tumor or hemopericardium
- Thiamine deficiency[5]
- Various central and autonomic nervous system abnormalities
- Other conditions that can lead to ST-segment elevation in the right precordial leads
- Early repolarization syndrome
- Other normal variants (particularly in males)
Of note, a Brugada-like ECG can occasionally appear for a brief period or for a period of several hours after direct-current cardioversion; it is not known whether these patients are gene carriers for Brugada syndrome.
References
- ↑ Takehara N, Makita N, Kawabe J, Sato N, Kawamura Y, Kitabatake A, Kikuchi K (2004). "A cardiac sodium channel mutation identified in Brugada syndrome associated with atrial standstill". Journal of Internal Medicine. 255 (1): 137–42. PMID 14687250. Retrieved 2012-10-13. Unknown parameter
|month=ignored (help) - ↑ Myers GB. Other QRS-T patterns that may be mistaken for myocardial infarction; IV. Alterations in blood potassium; myocardial ischemia; subepicardial myocarditis; distortion associated with arrhythmias. Circulation. 1950; 2: 75–93.
- ↑ Perloff JK, Henze E, Schelbert HR. Alterations in regional myocardial metabolism, perfusion, and wall motion in Duchenne muscular dystrophy studied by radionuclide imaging. Circulation. 1984; 69: 33–42.
- ↑ Wang K, Asinger RW, Marriott HJ (2003). "ST-segment elevation in conditions other than acute myocardial infarction". The New England Journal of Medicine. 349 (22): 2128–35. doi:10.1056/NEJMra022580. PMID 14645641. Retrieved 2012-10-13. Unknown parameter
|month=ignored (help) - ↑ Read DH, Harrington DD (1981). "Experimentally induced thiamine deficiency in beagle dogs: clinical observations". American Journal of Veterinary Research. 42 (6): 984–91. PMID 7197132. Unknown parameter
|month=ignored (help);|access-date=requires|url=(help)