Mitral stenosis general approach to mitral stenosis: Difference between revisions
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* Severe calcifications of the mitral valve | * Severe calcifications of the mitral valve | ||
Results of the procedure are excellent with pliable valves and with no calcium deposits on the valve. | Results of the procedure are excellent with pliable valves, fused commisures and with no calcium deposits on the valve. | ||
==References== | ==References== | ||
Revision as of 19:31, 16 October 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]
Overview
Mitral stenosis is a valvular disease characterized by a narrowing in the heart valve between the two left chambers of the heart (left atrium and left ventricle).
Pathophysiology
- Commisural fusion is the hallmark anatomic finding in mitral stenosis.
- The narrowing in the mitral valve causes build up of pressures in the left atrium, and eventually in the pulmonary bed.
- The build up of pressures in the pulmonary bed leads to pulmonary hypertension which results in right heart failure.
- The left ventricle is unaffected in pure mitral stenosis.
Causes
The cause of mitral stenosis is almost always rheumatic heart disease.
Differentiating Mitral stenosis from other Diseases
Mitral stenosis should be differentiated from:
- Cor triatriatum
- Atrial myxoma
- Pulmonary vein obstruction
Natural History and Complications
Natural History
Mitral stenosis is intermittently progressive and has a prolonged clinical course before becoming severe.
Complications
Complications occur in the late stages of mitral stenosis. They include:
- Atrial fibrillation
- Pulmonary hypertension
- Right heart failure
- Stroke - due to thrombus formation in the left atrium
Diagnosis
Symptoms
Symptoms of mitral stenosis occur late in the course of the disease as the disease progresses slowly over decades. Common symptoms include:
Physical Examination
- A high pitched additional sound called opening snap (OS) may be heard after the A2 component of S2 and it signifies the forceful opening of the mitral valve.
- The S2 - OS interval determines the severity of mitral stenosis.
- Mild: >110 msec
- Moderate: 70-110 msec
- Severe: <70 msec
The closer the gap between S2 and OS the severe the stenosis is.
Imaging
Echocardiography
- ECHO is the gold standard for diagnosis and quantification of mitral stenosis. It is a better diagnostic tool than cardiac catheterization.
- To define the anatomy of the stenotic lesion a 2D echocardiography is used and to define the hemodynamics of blood flow through the stenotic valve a Doppler ECHO is preferred.
- Doppler is the gold standard for quantifying the transmitral pressure gradient.
Treatment
- General principles in the management of mitral stenosis include:
- Anticoagulation - if atrial fibrillation is present
- For class I and II symptoms observing is the preferred treatment.
- Replacement of mitral valve - if class III and IV symptoms.
Percutaneous mitral balloon valvotomy
Indications
- Class II, III and IV symptoms
- Asymptomatic patients with:
- Pulmonary artery pressure >60mm Hg
- New onset atrial fibrillation
Contraindications
- Mitral regurgitation +2
- Left atrium thrombus
- Severe calcifications of the mitral valve
Results of the procedure are excellent with pliable valves, fused commisures and with no calcium deposits on the valve.